Structure of PDB 7odt Chain l Binding Site BS01

Receptor Information
>7odt Chain l (length=82) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALKDPDVCTDPVQLTTYAMGVNIYKEGQDVPLKPDAEYPEWLFEMNLGPP
KTLEELDPESREYWRRLRKQNIWRHNRLSKNK
Ligand information
>7odt Chain A (length=1453) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccuc
uaaauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuug
gacacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauag
uaggccuaaaagcagccaccaauuaagaaagcguucaagcucaacacaaa
aaaucccaaacauauaacugaacuccucacacccaauuggaccaaucuau
cacccuauagaagaacuaauguuaguauaaguaacaugaaaacauucucc
uccgcauaagccugcgucagauuaaaacacugaacugacaauuaacagcc
caauaucuacaaucaaccaacaagucauuauuacccucacugucaaccca
acacaggcaugcucauaaggaaagguuaaaaaaaguaaaaggaacucggc
aaaucuuaccccgccuguuuaccaaaaacaucaccucuagcaucaccagu
auuagaggcaccgccugcaaucacuuguuccuuaaauagggaccuguauu
ggcuccacgaggguucagcugucucuuacuuuuaaccagugaaauugacc
ugcccgugaagaggcgggcauaacacagcaagacgagaagacccuaugga
gcuuuaauuuauuaaugcaaacagaaaccugcauuaaaaauuucgguugg
ggcgaccucggagcagaacccaaccuccgagcaguacaugcuaagacuuc
accagucaaagcgaacacucaauugauccaauaacuugaccaacggaaca
aguuacccuagggauaacagcgcaauccuauucuagaguccauaucaaca
auaggguuuacgaccucgauguuggaucaggacaucccgauggugcagcc
gcuauuaaagguucguuuguucaacgauuaaaguccuacgugaucugagu
ucagaccggaguaauccaggucgguuucuaucuacuuucaaauuccuccc
uguacgaaaggacaagagaaauaaggccuacuucacaaagcgccuucccc
cguaaaugauaucaucucaacuuaguauacccaccccacccaagaacagg
guu
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<..<<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>...>..>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
....>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>
>>>...<<<......>>>....<<<.<<<...<..............<..
..<<<.........>>>....>.......<<<......>>>.........
..................>...>>>>>>........>>>>>>...<<<<<
......>>>>>.........>>>>>><......<<..<<<....>>><<<
<..<<<<........<<<<<..............>>>>>......<<<..
.<<<<.......................>>>>.......>>>.....<<.
.....>>.>>>>.....>>>>..<<<<...<<<<<<<<.<<.........
.......<<<<<<..<<<.........>>>...<<<<<<...........
..>>>>>>....<<<.......<<..<<<<<<.....>>>>>>..>>...
>>>....>>.>>>>........>>.>>>>>>>>>>>>.>>.....>....
.<<<<<........>>>>>.......<<..<<<.<<......<<<<.<<<
<<<..<<<<<.<<<<<<<<..........>>>>>>>>>>>>>..<<<<..
...>>>><<<<<<...........>>>>>>..<<.....<<<..<<<<..
...>>>>..>>>.....>>.........<<<....>>>............
>>>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...>
>>>>>...>.>>.>......<<<<<<.<<<<<<..<<.<<<<<<......
>>>>>>...>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>>
...<<<<<<<....>>>.>>>>....>>..>>>.>>...<.<<<.<<<..
...............>>>.>>><<<<<...<<<....>>>.>>>>>....
..<<<................>>>...>.........<<<<.......>>
>>.
Receptor-Ligand Complex Structure
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PDB7odt Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		P104 R115 R120 R122 K123 I126 W127 H129 N130 K134
Binding residue
(residue number reindexed from 1)		P50 R61 R66 R68 K69 I72 W73 H75 N76 K80
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7odt, PDBe:7odt, PDBj:7odt
PDBsum7odt
PubMed34135320
UniProtQ6P161|RM54_HUMAN Large ribosomal subunit protein mL54 (Gene Name=MRPL54)

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