Structure of PDB 7nhn Chain l Binding Site BS01

Receptor Information
>7nhn Chain l (length=114) Species: 169963 (Listeria monocytogenes EGD-e) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IESGIAHIRSTFNNTIVMITDTHGNALAWSSAGSLGFKGSRKSTPFAAQM
AAESAAKSAQEHGLKTLEVTVKGPGSGREAAIRALQAAGLEVTAIKDVTP
VPHNGCRPPKRRRV
Ligand information
>7nhn Chain a (length=1513) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gagaguuugauccuggcucaggacgaacgcuggcggcgugccuaauacau
gcaagucgaacgaacggauguuaguggcggacgggugaguaacacguggg
caaccugccuguaaguuggggauaacuccgggaaaccggggcuaauaccg
aaugauaaaguguggcgcaugccacgcuuuugaaagaugguuucggcuau
cgcuuacagaugggcccgcggugcauuagcuaguugguaggguaauggcc
uaccaaggcaacgaugcauagccgaccugagagggugaucggccacacug
ggacugagacacggcccagacuccuacgggaggcagcaguagggaaucuu
ccgcaauggacgaaagucugacggagcaacgccgcguguaugaagaaggu
uuucggaucguaaaguacuguuguuagagaagaacaaggauaagaguaac
ugcuugucccuugacgguaucuaaccagaaagccacggcuaacuacgugc
cagcagccgcgguaauacguagguggcaagcguuguccggauuuauuggg
cguaaagcgcgcgcaggcggucuuuuaagucugaugugaaagcccccggc
uuaaccggggagggucauuggaaacuggaagacuggagugcagaagagga
gaguggaauuccacguguagcggugaaaugcguagauauguggaggaaca
ccaguggcgaaggcgacucucuggucuguaacugacgcugaggcgcgaaa
gcguggggagcaaacaggauuagauacccugguaguccacgccguaaacg
augagugcuaaguguuaggggguuuccgccccuuagugcugcagcuaacg
cauuaagcacuccgccuggggaguacgaccgcaagguugaaacucaaagg
aauugacgggggcccgcacaagcgguggagcaugugguuuaauucgaagc
aacgcgaagaaccuuaccaggucuugacauccuuugaccacucuggagac
agagcuuucccgggacaaagugacagguggugcaugguugucgucagcuc
gugucgugagauguuggguuaagucccgcaacgagcgcaacccuugauuu
uaguugccagcauuuaguugggcacucuaaagugacugccggugcaagcc
ggaggaagguggggaugacgucaaaucaucaugccccuuaugaccugggc
uacacacgugcuacaauggauaguacaaagggucgcgaagccgcgaggug
gagcuaaucccauaaaacuauucucaguucggauuguaggcugcaacucg
ccuacaugaagccggaaucgcuaguaaucguggaucagcaugccacggug
aauacguucccgggccuuguacacaccgcccgucacaccacgagaguuug
uaacacccgaagucgguaggguaaccggagccagccgccgaaggugggac
agauaauuggggugaagucguaacaagguagccguaucggaaggugcggc
uggaucaccuccu
..<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.<
<<..<<<..<<.<<<<..>>>>.>>>>>......<<........<<<<<<
<..<<...<<<<<<<<<.<<.....<<<<<<....>>>>>>......>>.
>.....<<<<<<<<<<....>>>>>>>>>>.....<<<<<<....>>>>>
>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>>
>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<
<<.<.........>>>>>>.<<<<....>>>>...>>>>>>.........
<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<
<....>>>>.....>>>>...<<<<<<<.......<<<<<<<<<......
..>>>>>>>.>>.......>>>>>>...>..<<<<<(((...<<<<<...
..<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<
<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<.......<<<<<<.
....>>>>>>.....>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<
<<<<....<<<<<<<<<..<<<......>>>.....>>>>>>>>>.....
......<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....
<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>........
..<<<<<<..<<<<<<<<<<<<<....>>>>>>>>>>>>>...<<..))>
>.....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))
).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<....
....>>..........<<<<<<<......<<<<<<<....<<<<<....>
>>>>....<<<>>>.>>>>>.>>.<<<.<<<..<<<<<<.......<<<<
<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<
<<<..<<<..<<......>>>>>...>>>>>>>.....<<<<<....>>>
>>........>>>>.........>>>...>>>>>>>>>...>>>>>>>..
.>>.>>>>>>>>.....<<<<<<<.....<<<..<<...<<<....>>>.
..>>....>>>.....>>>>>>>......<....<<<<<<<........>
>>>>>>....>.....>>>>>>....<<<<<<<.........>>>>>>>.
.....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<
<..<<<<....<.<<<<..<<<..<<>>.>>>.>>>>.>...>>>>..>>
>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>
>............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7nhn Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
H22 N28 N29 M33 G39 N40 A41 W44 S46 G48 S49 G54 S55 K57 V116 P117 H118 N119 G120 C121 P124 K125 R127 R128 V129
Binding residue
(residue number reindexed from 1)
H7 N13 N14 M18 G24 N25 A26 W29 S31 G33 S34 G39 S40 K42 V101 P102 H103 N104 G105 C106 P109 K110 R112 R113 V114
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7nhn, PDBe:7nhn, PDBj:7nhn
PDBsum7nhn
PubMed34117249
UniProtP66352|RS11_LISMO Small ribosomal subunit protein uS11 (Gene Name=rpsK)

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