Structure of PDB 7nhm Chain l Binding Site BS01

Receptor Information
>7nhm Chain l (length=118) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKKNIENGVAHIRSTFNNTIVTITDEFGNALSWSSAGALGFKGSKKSTPF
AAQMASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQSAGLEVTAIR
DVTPVPHNGCRPPKRRRV
Ligand information
>7nhm Chain a (length=1531) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaauaca
ugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcggcg
gacgggugaguaacacguggauaaccuaccuauaagacugggauaacuuc
gggaaaccguagcuaauaccggauaauauuuugaaccgcaugguucaaaa
gugaaagacggucuugcugucacuuauagauggauccgcgcugcauuagc
uaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccuga
gagggugaucggccacacuggaacugagacacgguccagacuccuacggg
aggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagcaac
gccgcgugagugaugaaggucuucggaucguaaaacucuguuauuaggga
agaacauauguguaaguaacugugcacaucuugacgguaccuaaucagaa
agccacggcuaacuacgugccagcagccgcgguaauacguagguggcaag
cguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaagu
cugaugugaaagcccacggcucaaccguggagggucauuggaaacuggaa
aacuugagugcagaagaggaaaguggaauuccauguguagcggugaaaug
cgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucugua
acugacgcugaugugcgaaagcguggggaucaaacaggauuagauacccu
gguaguccacgccguaaacgaugagugcuaaguguuagggggccccuuag
ugcugcagcuaacgcauuaagcacuccgccuggggaguacgaccgcaagg
uugaaacucaaaggaauugacggggacccgcacaagcgguggagcaugug
guuuaauucgaagcaacgcgaagaaccuuaccaaaucuugacauccuuug
acaacucuagagauagagccuuccggacaaagugacagguggugcauggu
ugucgucagcucgugucgugagauguuggguuaagucccgcaacgagcgc
aacccuuaagcuuaguugccaucauuaaguugggcacucuaaguugacug
ccggugacaaaccggaggaagguggggaugacgucaaaucaucaugcccc
uuaugauuugggcuacacacgugcuacaauggacaauacaaagggcagcg
aaaccgcgaggucaagcaaaucccauaaaguuguucucaguucggauugu
agucugcaacucgacuacaugaagcuggaaucgcuaguaaucguagauca
gcaugcuacggugaauacguucccgggucuuguacacaccgcccgucaca
ccacgagaguuuguaacacccgaagccgguggaguaaccuuuuaggagcu
agccgucgaaggugggacaaaugauuggggugaagucguaacaagguagc
cguaucggaaggugcggcuggaucaccuccu
...<<<<....((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.
<<<..<<<..<<.<<<........................>>>.>>>>>.
.....<<........<<<<<<<..<<...<<<<<<<.<<<<.....<<.<
<<....>>>.>>......>>>>......<<<<<<<<<....>>>>>>>>>
......<<<<<<...>>>>>>.>>>>>>>..>>>>>>>>>.<<<....<<
<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<..
..>>>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>
>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>
>>>>>..<<<<......<<<<....>>>>.....>>>>...<<<<<<<..
.....<.<<<<<<..........>>>>>>.>........>>>>>>...>.
.<<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>..>
>>>>>>>>..........<<<((.....<<<<<..<<<.<<<<<<<.<<<
<<<<<<.......<<<<<<.....>>>>>>.....>>>>>>>..>>>>>>
>>>...<<<<<<<<...<<<<<<<....<<<<<<<<...<<<......>>
>......>>>>>>>>...........<<....>>.>>>>>>>..>>>>>.
>>>...>>>..>>>>>....<<<<<<<...<...<<<<.<.....>.>>>
>...>>>>>>>>..........<<<<<<..<<<<<<<<<<<..>>>>>>>
>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>
>>....>>>..))))..<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<
<<......<<........>>..........<<<<<<<......<<<<<<.
....<<<<<....>>>>>..........>>>>.>>.<<<.<<<..<<<<<
<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>>>..
...<<<<.<<<<<<<..<<..<<<......>>>>>...>>>>>>>.....
<<<<<.....>>>>>........>>>>.........>>>...>>>>>>>>
>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<.
..<<<....>>>...>>....>>>.....>>>>>>>......<....<<<
<<<<........>>>>>>>....>.....>>>>>>....<<<<<<<....
.....>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<
<<.<<<..<<<<<<..<<<<....<.<<<<..<<<..<<<...>>>.>>>
.>>>>.>...>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<<<
<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
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PDB7nhm Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		K14 H22 N28 N29 G39 N40 A41 W44 G48 A49 G54 S55 K57 K87 P115 H118 N119 C121 R122 P124 K125 R127 R128
Binding residue
(residue number reindexed from 1)		K3 H11 N17 N18 G28 N29 A30 W33 G37 A38 G43 S44 K46 K76 P104 H107 N108 C110 R111 P113 K114 R116 R117
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7nhm, PDBe:7nhm, PDBj:7nhm
PDBsum7nhm
PubMed34117249
UniProtQ2FW31|RS11_STAA8 Small ribosomal subunit protein uS11 (Gene Name=rpsK)

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