Structure of PDB 7nhk Chain l Binding Site BS01

Receptor Information
>7nhk Chain l (length=116) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNIESGVAHIHSTFNNTIVMITDTHGNALAWSSAGSLGFKGSKKSTPFAA
QMAAEAATKVAMEHGLKTVDVTVKGPGSGREAAIRSLQATGLEVTAIRDV
TPVPHNGCRPPKRRRV
Ligand information
>7nhk Chain a (length=1517) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gagaguuugauccuggcucaggacgaacgcuggcggcgugccuaauacau
gcaagucgaacgcuucuuaagaggaguggcggacgggugaguaacacgug
gguaaccuacccaucagagggggauaacacuuggaaacaggugcuaauac
cgcauaacaguuuaugccgcauggcauaagagugaaaggcgcuggugucg
cugauggauggacccgcggugcauuagcuaguuggugagguaacggcuca
ccaaggccacgaugcauagccgaccugagagggugaucggccacacuggg
acugagacacggcccagacuccuacgggaggcagcaguagggaaucuucg
gcaauggacgaaagucugaccgagcaacgccgcgugagugaagaagguuu
ucggaucguaaaacucuguuguuagagaagaacaaggacguuaguaacug
aacguccccugacgguaucuaaccagaaagccacggcuaacuacgugcca
gcagccgcgguaauacguagguggcaagcguuguccggauuuauugggcg
uaaagcgagcgcaggcgguuucuuaagucugaugugaaagcccccggcuc
aaccggggagggucauuggaaacugggagacuugagugcagaagaggaga
guggaauuccauguguagcggugaaaugcguagauauauggaggaacacc
aguggcgaaggcggcucucuggucuguaacugacgcugaggcucgaaagc
guggggagcaaacaggauuagauacccugguaguccacgccguaaacgau
gagugcuaaguguuggaggguuuccgcccuucagugcugcagcaaacgca
uuaagcacuccgccuggggaguacgaccgcaagguugaaacucaaaggaa
uugacgggggcccgcacaagcgguggagcaugugguuuaauucgaagcaa
cgcgaagaaccuuaccaggucuugacauccuuugaccacucuagagauag
agcuuucccgggacaaagugacagguggugcaugguugucgucagcucgu
gucgugagauguuggguuaagucccgcaacgagcgcaacccuuauuguua
guugccaucauuuaguugggcacucuagcgagacugccggugacaaaccg
gaggaagguggggaugacgucaaaucaucaugccccuuaugaccugggcu
acacacgugcuacaaugggaaguacaacgagucgcuagaccgcgagguca
ugcaaaucucuuaaagcuucucucaguucggauugcaggcugcaacucgc
cugcaugaagccggaaucgcuaguaaucgcggaucagcacgccgcgguga
auacguucccgggccuuguacacaccgcccgucacaccacgagaguuugu
aacacccgaagucggugagguaaccuuuuuggagccagccgccuaaggug
ggauagaugauuggggugaagucguaacaagguagccguaucggaaggug
cggcuggaucaccuccu
..<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.<
<<..<<<..<<.<<<<....>>>>.>>>>>......<<........<<<<
<<<..<<...<<<<<<<.<.<<.....<<<<<......>>>>>......>
>.>.....<.<<<<<<<<<..>>>>>>>>>..>....<<<<<..>>>>>.
>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>>>>
>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<
.<.........>>>>>>.<<<<....>>>>...>>>>>>.........<<
<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<.
...>>>>.....>>>>...<<<<<<<.........<<<<<<<........
>>>>>>>..........>>>>>>...>..<<<<<(((...<<<<<.....
<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<(
(.....<<<<...<<<.<<<<<<<.<<<<<<<<<.......<<<<<<...
..>>>>>>.....>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<
<<....<<<<<<<<<..<<<......>>>.....>>>>>>>>>.......
....<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<
<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........
<<<<<<..<<<<<<<<<<<<<....>>>>>>>>>>>>>...<<..))>>.
....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).
]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<......
..>>..........<<<<<<<......<<<........<<<<<....>>>
>>....<<<>>>.....>.>>.<<<.<<<..<<<<<<.......<<<<<<
<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<
<..<<<..<<......>>>>>...>>>>>>>.....<<<<<.....>>>>
>........>>>>.........>>>...>>>>>>>>>...>>>>>>>...
>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>.
.>>....>>>.....>>>>>>>......<....<<<<<<<........>>
>>>>>....>.....>>>>>>....<<<<<<<.........>>>>>>>..
....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<
..<<<<...<<.<<<<..<<<..<<.....>>.>>>.>>>>.>>..>>>>
..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>
>>>>>............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7nhk Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		H22 N28 N29 M33 G39 N40 A41 W44 S46 G48 S49 G54 K57 K87 P115 P117 H118 N119 G120 C121 R122 P124 K125 R127 R128 V129
Binding residue
(residue number reindexed from 1)		H9 N15 N16 M20 G26 N27 A28 W31 S33 G35 S36 G41 K44 K74 P102 P104 H105 N106 G107 C108 R109 P111 K112 R114 R115 V116
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7nhk, PDBe:7nhk, PDBj:7nhk
PDBsum7nhk
PubMed34117249
UniProtA0A1B4XKV1

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