Structure of PDB 6zsc Chain l Binding Site BS01

Receptor Information
>6zsc Chain l (length=80) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KDPDVCTDPVQLTTYAMGVNIYKEGQDVPLKPDAEYPEWLFEMNLGPPKT
LEELDPESREYWRRLRKQNIWRHNRLSKNK
Ligand information
>6zsc Chain XA (length=1500) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccaa
auccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuuggac
acuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauaguag
gccuaaaagcagccaccaauuaagaaagcguucaagcucaacaccaaaaa
ucccaaacauauaacugaacuccucacacccaauuggaccaaucuaucac
ccuauagaagaacuaauguuaguauaaguaacaugaaaacauucuccucc
gcauaagccugcgucagauaaccaacugacaauuaacagcccaauaucua
caaucaaccaacaagucauuauuacccucacugucaacccaacacaggca
ugcucauaaggaaagguuaaaaaaaguaaaaggaacucggcaaaucuuac
cccgccuguuuaccaaaaacaucaccucuagcaucaccaguauuagaggc
accgccugcccagugacacauguuuaacggccgcgguacccuaaccgugc
aaagguagcauaaucacuuguuccuuaaauagggaccuguaugaauggcu
ccacgaggguucagcugucucuuacuuuuaaccagugaaauugaccugcc
cgugaagaggcgggcauaacacagcaagacgagaagacccuauggagcuu
uaauuuauuaaugcaaacaguaaccaaaccugcauuaaaaauuucgguug
gggcgaccucggagcagaacccaaccuccgagcaguacaugcuaagacuu
caccagucaaagcgaaccucaauugauccaauaacuugaccaacggaaca
aguuacccuagggauaacagcgcaauccuauucuagaguccauaucaaca
auaggguuuacgaccucgauguuggaucaggacaucccgauggugcagcc
gcuauuaaagguucguuuguucaacgauuaaaguccuacgugaucugagu
ucagaccggaguaauccaggucgguuucuaucuacuuauuccucccugua
cgaaaggacaagagaaauaaggccuacuucacaaagcgccuucccccgua
aaugauaucaucucaacuuagaauacccacacccacccaagaacaggguu
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
.>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>>>>
...<<<......>>>....<<<.<<<...<..............<....<
<<.........>>>....>.......<<<......>>>............
...............>...>>>>>>........>>>>>>...<<<<<...
...>>>>>.........>>>>>><......<<..<<<....>>><<<<..
<<<<........<<<<<........>>>>>......<<<...<<<<....
...................>>>>.......>>>.....<<......>>.>
>>>.....>>>>..<<<<...<<<<<<<<.<<.........<......<<
<<<<..<<<.........>>>...<<<<<<.............>>>>>>.
...<<<.<<<..<<<<<....>>>..>>>>><<<<<<......>>>>>>.
.......<...........<<<<<<.....>>>>>>.....>....>>>.
...>>.>>>>.....>..>>.>>>>>>>>>>>>.>>.....>.....<<<
<<........>>>>>.......<<..<<<.<<......<<<<.<<<<<<.
.<<<<<.<<<<<<<<...............>>>>>>>>>>>>>..<<<<.
....>>>><<<<<<...........>>>>>>..<<.....<<<..<<<<.
....>>>>..>>>....>>.........<<<....>>>............
>>>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...>
>>>>>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<<......
>>>>>>...>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>.
...<<<<<<<....>>>.>>>>....>>..>>>.>>.<<<.<<<......
...........>>>.>>><<<<<...<<<....>>>.>>>>>......<<
<................>>>..............<<<<.......>>>>.
Receptor-Ligand Complex Structure
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PDB6zsc Structural basis of mitochondrial translation.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		R115 R119 R120 R122 W127 H129 N130 S133 K134
Binding residue
(residue number reindexed from 1)		R59 R63 R64 R66 W71 H73 N74 S77 K78
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zsc, PDBe:6zsc, PDBj:6zsc
PDBsum6zsc
PubMed32812867
UniProtQ6P161|RM54_HUMAN Large ribosomal subunit protein mL54 (Gene Name=MRPL54)

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