Structure of PDB 6spe Chain l Binding Site BS01

Receptor Information
>6spe Chain l (length=121) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATINQLVRKPRKRMVDKSDVPALQNCPQRRGVCTRVYTTTPKKPNSALRK
VCRVRLTNGFEVSSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGS
LDTSGVKDRKQGRSKYGAKRP
Ligand information
>6spe Chain a (length=1526) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aacugaagaguuugaucauggcucagauugaacgcuggcggcaggccuaa
cacaugcaagucgagcggauaaagggagcuugcuccuggauucagcggcg
gacgggugaguaaugccuaggaaucugccugguagugggggauaacgucc
ggaaacgggcgcuaauaccgcauacguccugagggagaaagugggggauc
uucggaccucacgcuaucagaugagccuaggucggauuagcuaguuggug
ggguaaaggccuaccaaggcgacgauccguaacuggucugagaggaugau
cagucacacuggaacugagacacgguccagacuccuacgggaggcagcag
uggggaauauuggacaaugggcgaaagccugauccagccaugccgcgugu
gugaagaaggucuucggauuguaaagcacuuuaaguugggaggaagggca
guaaguuaauaccuugcuguuuugacguuaccaacagaauaagcaccggc
uaacuucgugccagcagccgcgguaauacgaagggugcaagcguuaaucg
gaauuacugggcguaaagcgcgcguaggugguucagcaaguuggauguga
aauccccgggcucaaccugggaacugcauccaaaacuacugagcuagagu
acgguagagggugguggaauuuccuguguagcggugaaaugcguagauau
aggaaggaacaccaguggcgaaggcgaccaccuggacugauacugacacu
gaggugcgaaagcguggggagcaaacaggauuagauacccugguagucca
cgccguaaacgaugucgacuagccguugggauccuugagaucuuaguggc
gcagcuaacgcgauaagucgaccgccuggggaguacggccgcaagguuaa
aacucaaaugaauugacgggggcccgcacaagcgguggagcaugugguuu
aauucgaagcaacgcgaagaaccuuaccuggccuugacaugcugagaacu
uuccagagauggauuggugccuucgggaacucagacacaggugcugcaug
gcugucgucagcucgugucgugagauguuggguuaagucccguaacgagc
gcaacccuuguccuuaguuaccagcaccucgggugggcacucuaaggaga
cugccggugacaaaccggaggaagguggggaugacgucaagucaucaugg
cccuuacggccagggcuacacacgugcuacaauggucgguacaaaggguu
gccaagccgcgagguggagcuaaucccauaaaaccgaucguaguccggau
cgcagucugcaacucgacugcgugaagucggaaucgcuaguaaucgugaa
ucagaaugucacggugaauacguucccgggccuuguacacaccgcccguc
acaccaugggaguggguugcuccagaaguagcuagucuaaccgcaagggg
gacgguuaccacggagugauucaugacuggggugaagucguaacaaggua
gccguaggggaaccugcggcuggauc
.......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....
<<<.<<<..<<<..<<.<<....<.<<<<..>>>>.>....>>.>>>>>.
.....<<.......<<<<<<<..<<...<<<<<<<<<.<<.....<<<<<
<....>>>>>>......>>.>.....<<<....>>>....<<<<<<..<<
....>>>>>>>>>>>>>>>>..>>.>>>>>>><<<....<<<..<<<<<<
<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...
>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>
>>.........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<
<<......<<<<<..>>>>>.....>>>>...<.<<<<<......<<<<<
<<<<<.......>>>>>>>>>>........>>>>>....>..<<<<<(((
...<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>>.
.........<<<((.....<<<<...<<<.<<<<<<..<<<<<<<<<<..
....<<<<<<.....>>>>>>....>>>>>>>>..>>.>>>>>>...<<<
<<<<<...<<<<<<<....<<<<<<<<<..<<<......>>>.....>>>
>>>>>>...........<<....>>.>>>>>>>..>>>>.>>>>...>>>
...>>>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>
>>>..........<<<<<<..<<<<<<<<<<<<.....>>>>>>>>>>>>
...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>..
..>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<..
....<<........>>..........<<<<<<<......<<<<<<<....
..<<<....>>>.......<<....>>..>>>>>.>>.<<<.<<<..<<<
<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>>>
.....<<<<.<<<<<<<...<<..<<<.....>>>>>....>>>>>>>..
...<<<<<.....>>>>>........>>>>.........>>>...>>>>>
>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..
<<...<<<....>>>...>>....>>>.....>>>>>>>......<....
<<<<<<<........>>>>>>>....>.....>>>>>>....<<<<<<<.
........>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<
.<<<<.<<<..<<<<<<<<<<<<....<<<<<<.<<<<..<<....>>.>
>>>>>>>>>...>>>>>>>>>>>>..>>>.>>>>..>.>>...>.....<
<<<<<<<<....>>>>>>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6spe Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Resolution3.6 Å
Binding residue
(original residue number in PDB)
A2 N5 Q6 R9 R12 K13 R14 M15 S19 C27 P28 Q29 R30 R31 K44 N46 S47 R50 K51 G69 E70 K88 R94 R110 K111 Q112 G113 R114 S115 A119 K120 R121
Binding residue
(residue number reindexed from 1)
A1 N4 Q5 R8 R11 K12 R13 M14 S18 C26 P27 Q28 R29 R30 K43 N45 S46 R49 K50 G68 E69 K87 R93 R109 K110 Q111 G112 R113 S114 A118 K119 R120
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6spe, PDBe:6spe, PDBj:6spe
PDBsum6spe
PubMed31611393
UniProtA0A071L394

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