Structure of PDB 6o8w Chain l Binding Site BS01

Receptor Information
>6o8w Chain l (length=136) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTINQLVRKPRKSKVEKSDSPALNKGYNSFKKTQTNVNSPQKRGVCTRVG
TMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVK
DLPGVRYHIVRGALDTAGVNDRKQSRSKYGTKRPKA
Ligand information
>6o8w Chain a (length=1523) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugagaguuugauccuggcucaggacgaacgcuggcggcgugccuaauaca
ugcaagucgaacgcuucuuggaaagaggaguggcggacgggugaguaaca
cguggguaaccuacccaucagagggggauaacacuuggaaacaggugcua
auaccgcauaacaguuuaugccgcauggcauaagagugaaaggcgcuuuc
gggugucgcugauggauggacccgcggugcauuagcuaguuggugaggua
acggcucaccaaggccacgaugcauagccgaccugagagggugaucggcc
acacugggacugagacacggcccagacuccuacgggaggcagcaguaggg
aaucuucggcaauggacgaaagucugaccgagcaacgccgcgugagugaa
gaagguuuucggaucguaaaacucuguuguuagagaagaacaaggacguu
aguaacugaacguccccugacgguaucuaaccagaaagccacggcuaacu
acgugccagcagccgcgguaauacguagguggcaagcguuguccggauuu
auugggcguaaagcgagcgcaggcgguuucuuaagucugaugugaaagcc
cccggcucaaccggggagggucauuggaaacugggagacuugagugcaga
agaggagaguggaauuccauguguagcggugaaaugcguagauauaugga
ggaacaccaguggcgaaggcggcucucuggucuguaacugacgcugaggc
ucgaaagcguggggagcaaacaggauuagauacccugguaguccacgccg
uaaacgaugagugcuaaguguuggaggguuuccgcccuucagugcugcag
caaacgcauuaagcacuccgccuggggaguacgaccgcaagguugaaacu
caaaggaauugacgggggcccgcacaagcgguggagcaugugguuuaauu
cgaagcaacgcgaagaaccuuaccaggucuugacauccuuugaccacucu
agagauagagcuuucccuucggggacaaagugacagguggugcaugguug
ucgucagcucgugucgugagauguuggguuaagucccgcaacgagcgcaa
cccuuauuguuaguugccaucauuuaguugggcacucuagcgagacugcc
ggugacaaaccggaggaagguggggaugacgucaaaucaucaugccccuu
augaccugggcuacacacgugcuacaaugggaaguacaacgagucgcuag
accgcgaggucaugcaaaucucuuaaagcuucucucaguucggauugcag
gcugcaacucgccugcaugaagccggaaucgcuaguaaucgcggaucagc
acgccgcggugaauacguucccgggccuuguacacaccgcccgucacacc
acgagaguuuguaacacccgaagucggugagguaaccuuuuuggagccag
ccgccuaaggugggauagaugauuggggugaagucguaacaagguagccg
uaucggaaggugcggcuggauca
...<<<<....((((.>>>>.<<<..........<.<<<<<.....<<<.
<<<..<<<..<<.<<<<<.....>>>>>.>>>>>......<<........
<<<<<<<..<<...<<<<<<<.<.<<.....<<<<<<....>>>>>>...
...>>.>.....<.<<<<<<<<....>>>>>>>>..>....<<<<<....
..>>>>>.>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<...
....>>>>>>>>>>>......>>>..<<<<<<........>>...>>>>.
>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>...
....<.<<<....<<<<....>>>>..>>>>.>>.>>>.>...<<<<...
...<<<<....>>>>.....>>>>...<<<<<<<.........<<.<<..
..........>>..>>.........>>>>>>...>..<<<<<(((...<<
<<<.....<..))).>.......>>>>>>>>>>........>>>......
....<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<.......<
<<<<<.....>>>>>>.....>>>>>>>..>>>>>>>>>...<<<<<<<<
...<<<<<<<....<<<<<<<<<..<<<......>>>.....>>>>>>>>
>...........<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>
>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..
........<<<<<<..<<<<<<<<<<<<......>>>>>>>>>>>>...<
<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>....>>
>..))))..<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......
<<........>>..........<<<<<<<.......<<<<<.....<<<<
<....>>>>>................>>>>.>..<<<.<<<..<<<<<<.
......<<<<<<<<<....>>>..<<<<......>>>>..>>>>>>....
.<<<<.<<<<<<<..<<<...<.....>..>>>...>>>>>>>.....<<
<<<.....>>>>>........>>>>.........>>>...>>>>>>>>>.
..>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<
<<<....>>>>..>>....>>>.....>>>>>>>......<....<<<<<
<<........>>>>>>>....>.....>>>>>>....<<<<<<<......
...>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<
.<<<..<<<<<<..<<<<...<<.<<<<..<<<..<<.....>>.>>>.>
>>>.>>..>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<
<<<<....>>>>>>>>>......
Receptor-Ligand Complex Structure
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PDB6o8w Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis.
Resolution3.53 Å
Binding residue
(original residue number in PDB)		P2 T3 N5 Q6 R9 R12 K13 K15 K18 L24 S40 P41 Q42 R44 K56 K57 N59 S60 A61 R63 R96 G97 K101 R107 D122 R123 Q125 S126 R127 S128 K129 G131 K133 R134
Binding residue
(residue number reindexed from 1)		P1 T2 N4 Q5 R8 R11 K12 K14 K17 L23 S39 P40 Q41 R43 K55 K56 N58 S59 A60 R62 R95 G96 K100 R106 D121 R122 Q124 S125 R126 S127 K128 G130 K132 R133
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6o8w, PDBe:6o8w, PDBj:6o8w
PDBsum6o8w
PubMed33004869
UniProtA0A1B4XKQ7

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