Structure of PDB 6fyy Chain l Binding Site BS01

Receptor Information
>6fyy Chain l (length=128) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VGLPYSELLSRFFNILRKFRIPPPVCLRDGKKTIFSNIQDIAEKLHRSPE
HLIQYLFAELGTSGSVDGKRLVIKGKFQSKQMENVLRRYILEYVTCKTCK
SINTELKRENRLFFMVCKSCGSTRSVSS
Ligand information
>6fyy Chain 1 (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcgccguggcgcaguggaagcgcgcagggcucauaacccugauguccuc
ggaucgaaaccgagcggcgcuacca
<<<<<<<..<<<<.......>>>>.<<<<<.......>>>>>.....<<<
<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB6fyy Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Resolution3.02 Å
Binding residue
(original residue number in PDB)		R248 N252 R253 L254 F255 S269
Binding residue
(residue number reindexed from 1)		R108 N110 R111 L112 F113 S127
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008270 zinc ion binding
GO:0031369 translation initiation factor binding
GO:0046872 metal ion binding
GO:1990856 methionyl-initiator methionine tRNA binding
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005850 eukaryotic translation initiation factor 2 complex
GO:0016282 eukaryotic 43S preinitiation complex
GO:0043614 multi-eIF complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6fyy, PDBe:6fyy, PDBj:6fyy
PDBsum6fyy
PubMed30475211
UniProtP09064|IF2B_YEAST Eukaryotic translation initiation factor 2 subunit beta (Gene Name=SUI3)

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