Structure of PDB 5imr Chain l Binding Site BS01

Receptor Information
>5imr Chain l (length=117) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVI
RIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLY
FIRNLSDREIRRKLRAD
Ligand information
>5imr Chain A (length=1515) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgggguuuuacuccguggucagcggcggacg
ggugaguaacgcgugggugaccuacccggaagagggggacaacccgggga
aacucgggcuaaucccccauguggacccgccccuugggguguguccaaag
ggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggg
guaauggcccaccaaggcgacgacggguagccggucugagaggauggccg
gccacaggggcacugagacacgggccccacuccuacgggaggcagcaguu
aggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggag
gaagaagcccuucgggguguaaacuccugaacccgggacgaaacccccga
cgaggggacugacgguaccgggguaauagcgccggccaacuccgugccag
cagccgcgguaauacggagggcgcgagcguuacccggauucacugggcgu
aaagggcguguaggcggccuggggcgucccaugugaaagaccacggcuca
accgugggggagcgugggauacgcucaggcuagacggugggagagggugg
uggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccg
auggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcg
uggggagcaaaccggauuagauacccggguaguccacgcccuaaacgaug
cgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgc
gccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacggg
ggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaaga
accuuaccaggccuugacaugcuagggaacccgggugaaagccuggggug
ccccgcgaggggagcccuagcacaggugcugcauggccgucgucagcucg
ugccgugagguguuggguuaagucccgcaacgagcgcaacccccgccguu
aguugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcg
ggaggaaggaggggacgacgucuggucagcauggcccuuacggccugggc
gacacacgugcuacaaugcccacuacaaagcgaugccacccggcaacggg
gagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccg
accccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcggu
gaauacguucccgggccuuguacacaccgcccgucacgccaugggagcgg
gcucuacccgaagucgccgggagccuacgggcaggcgccgaggguagggc
ccgugacuggggcgaagucguaacaagguagcuguaccggaaggugcggc
uggaucaccuccuuu
....<<<<..[.(((..>>>>.<<<<...<<...<<<<<<<......<<<
.<<<...<<..<<..<<<<.<<<<.....>>>>.>>>>..>>>>......
.<<.......<<<<<<<...<<...<<<<<<<.<<<<<...<<<<<<...
...>>>>>.>...>>>>>....<<<<.<<<<<....>>>>>.>>>>...<
<<<...>>>>.>>>>>>>..>>.>>>>>>><<<....<<<...<<<<<<<
.......>>>>>>>.>>>......>>>..<<<<<<<<....>>>>...>>
>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>
.........<<<....<<<<....>>>>..>>>...>.>>>>>>..<<<<
......<<<<....>>>>.....>>>>....<<<<<........<<<<..
...>>>>..........>>>>>......<<<<<(((...<<<<<.....<
<.)))>>.......>>>>>>>>>>...>>..>>>>..........<<<(.
.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<....
.>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<
.....<<<<<<<.<...<<......>>......>.>>>>>>>........
...<<....>>..>>>>>>..>>>>>.>>>...>>>...>>>>....<<<
<<<...<<...<.<<.........>>.>...>>>>>>>>..........<
<<<<<..<<<<<<<<<<...>>>>>>>>>>...<<...)>>.....>>>>
>>.>>.><<<......<<<<....>>>>....>>>...))).]<<<<<.<
<<<<<<.....<<<<<..<<<<<<<<........<<........>>....
......<<<<.<<.......<<<<.<<...<<<<<......>>>>>..<.
<<<<....>>>>.>>>.>>>>..<<<.<<<...<<<<<.<.....<<<<<
<<<<....>>>...<<<......>>>...>>>>>>.....<<<<.<<<<<
<<..<<...<<<.....>>>.>>...>>>>>>>.......<<<....>>>
..........>>>>.....>...>>>...>>.>>>>>>...>>.>>>>..
....>>>>>>>>.....<<<<<<<.....<<<..<<..<<<......>>>
..>>....>>>.....>>>>>>>......<......<<<<<........>
>>>>......>.....>>>>>......<<<<<<..........>>>>>>.
...........>>>>>>>>>>.>>.......<<.<.<<<<.<<<....<<
<<<<<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>
>>....>>.>>>>>..>.>>.........<<<<<<<<<....>>>>>>>>
>..............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5imr Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome
Resolution5.7 Å
Binding residue
(original residue number in PDB)
R93 I110 R112 R115
Binding residue
(residue number reindexed from 1)
R93 I110 R112 R115
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5imr, PDBe:5imr, PDBj:5imr
PDBsum5imr
PubMed27137929
UniProtP60490|RL19_THET8 Large ribosomal subunit protein bL19 (Gene Name=rplS)

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