Structure of PDB 9c4g Chain k Binding Site BS01

Receptor Information
>9c4g Chain k (length=144) Species: 1747 (Cutibacterium acnes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIELHDLKPAPGAHKAKTRVGRGEGSKGKTAGRGTKGTGARKNVPEFFAG
GQMPIHMQAPKLGGFHNPFRTEYQVVNLDKVEALFPKGGKITVDDLVSVG
AVRDNELVKVLGTGELTVKVDLVVDAWSKSAQEKIEKAGGSVTK
Ligand information
>9c4g Chain a (length=2903) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caaaguuguguagugcgaucgguggaugccuuggcaccaagagccgauga
aggacguugugaccugcgauaagcccuggggaguuggugagcgagcugug
auccggggguguccgaauggggaaaccuggaauguccggaguaguguccg
guggcccugcccugaauguauaggggugugggugguaacgcggggaagug
aaacaucuuaguacccguaggaagagaaaacaagugugauuccgugagua
guggcgagcgaaagcggaggaggcuaaaccgugugugugucagguguugc
augugcgggguugugggggccuugugguucugcugccgcaggauuggcca
gugagaaauguugcgugaaggugaagcgucugggaaggcguaccggagug
ggugagaguccuguaacuguaagcguggcacuggugugggguugccccga
guagcgugggacucguggaauuucgcgugaaucuggcgggaccacccguc
aagccuaaauacuccuuggugaccgauaguggaugaguaccgugagggaa
gggugaaaaguaccccgggaggggagugaaagaguuccugaaaccggucg
caugcaagccgucagagccuguguggugauggcgugccuuuugaagaaug
agccugcgaguuagugaugcguggcgagguuaacccguggugggggaguc
guagcgaaagcgaguccgauaagggcgugagucgcguguucuagacccga
agcggugugaucuauccauggccaggaugaagcgucgguaagacgucgug
gagguccgaacccacuucaguugaaaauggaggggaugaguuguggauag
gggugaaaggccaaucaaacaccgugauagcugguucuccccgaaaugca
uuuaggugcagcguugcgugguucuuguuggagguagagcacuggauggu
cuagggggcuuaucggcuuaccgaaaucagccaaacuccgaaugcuggca
aguguagcguggcagugagacggcgggugauaagcuucgucgucgagagg
gaaacagcccagaucaucagcuaaggccccuaaguggugacucaguggga
aaggauguggaguugcguagacaaccaggagguuggcuuggaagcagcca
uccuugaaagagugcguaauagcucacuggucaagugauuccgcgccgau
aauguagcggggcuuaaguuauccgccgaagcuguggcaaccuguguggu
uggguaggggagcgucgugucaguggugaagcugccgggugacugugugg
uggaguugaugcgagugagaaugcaggcaugaguagcgugugacgggugg
gaaucccguccgccgauuauccaaggguuccagggucaaguuugucugcc
cugggugagucggguccuaaggcgaggccgacaggcguagucgaugggua
accaguugauauucugguaccggcuugucaccgcaagcugcggagggacg
cagugagguagcucauccccggugaugguuguccggggcuaagugugugg
acugucugguagguaaauccgcugggcgugaagguugaggcaugaugggg
agcccaugguugugggugagugagugauccuguacugucgagaaaagcuu
cgugagcgagguggcggguccgcccguacccuaaaccgacacugguggau
agguagaguauaccgaggcgaucgagugaaucguggugaaggaacucggc
aaaaugcccccguaacuuugggauaagggggaccugagcugucgugcacc
cgugcggugugguggcggugaggggcgcagaguccagggggaaacgacug
uuuaccaaaaacacagguccgugcgaagucguaagacgauguauacggac
ugacuccugcccggugcuggaagguuaaggggaacugugaguguaugcgu
agcggugaacuuaagccccaguaaacggcggugguaacuauaaccauccu
aagguagcgaaauuccuugucggguaaguuccgaccugcacgaauggagu
aacgauuucccuacugucuccaccaugaacucggugaaauugcauuacga
guaaagaugcucguuacgcgcagcaggacggaaagaccccgggaccuuua
cuauaguuugguauuggugauugggacgguuuucugauuguucugguuau
cucacuguggaccgugauccgguucaaggacagugccugauggguaguuu
gacuggggcggucgccuccuaaaggguaacggaggcgcccaaagguuccc
ucagccugguugguaaucagguggugaguguaagugcacaagggggcuug
acugugagacugacaggucgagcagggacgaaagucgggacuagugaucu
gacgguggcuuguggaugcgccgucacucaacggauaaaagguaccccgg
ggauaacaggcugaucuugcccgagcgcucauagcgacggcaugguuugg
caccucgaugucggcucgucgcauccuggggcuggagucggucccaaggg
uugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucg
ugagacaguucggucccuauccgcugcgcgcggaggaaucuugagaaggg
cugucuuuaguacgagaggaccgagacggacugaccucuggugugccagu
uguucugccaagagcauggcugguuggcuacgucggguugugauaaccgc
ugaaagcaucuaagcgggaagcacgcuucaagauaaggguucccacagga
guguuccugguaagguccccgagagaugaucggguugauaggccagacgu
ggacgcaucguaagguguggagcugacugguacuaauagaccgaggacuu
uca
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<....>>......>>>>>.>.........<<<..>>>..<<<<<<.....
<<.....>>....>>>>>>..<<<....<<<<..................
....>>>>......<<<<<<<<<......<<<<....>>>>.........
.........<<..<<<...<<<...<<<<<......>>>>>((......<
<<.....))>>>...>>>......>>>..>>......>>>>>..>>>>..
...<<<<<<<<.........>>>>>>>>.......<<<<..<<<<>>>>.
..>>>......]].>>>>>>>.]]...............<<....>>...
.]].........<<<<....>>>>..................>>>>>>>>
>>>.......<<<<..<<<.....>>>..>>>>...<.<........>.>
.<<<<<<....<<<.<<<<<<<<<<..<<<...<<<.....>>>...>>>
...<<....>>..<<<<.....>>>>....>>>>>>>>>>>>>..<<.<.
.<<<<<<<.....<<<<<<<<<..<<<....<<<.<<......>>.>>>.
....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>..
.<<<.....>>>......>>>>>>...>..>.>>..<<<<<<....<<<<
<....>>>>><<<<<<<<<....<<<<<<<<.....<<<...<<<.<<<<
...<<.<<<<....>>>>..>>...>>>>.>>>..>>.>.....>>>>>>
>>....>>>>>>>.>>..<<<<<<<<<........>>>>>>>>>....<<
<......>>>...<<<<.<<<...<<<(((.....<<<<<<.........
..<<..<<<<<<<<<........<<<<<.<<...<<<.........>>>.
..>>.........<<......>>...>>>>>....>>>>>>>>>.>>...
........)))......>>>>>>.>>>...>>>>>>><<<<<.....>>>
>>....>>>>>>..<<<<<<<<<.......<<<<<<<<....>>>.>>>>
>....>>>>>>>>>........>>>>>><......<<....<<<<<<...
....>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>
>>>>....((<<<<.<<...<<<...<<<....>>>...>>>...>>...
<<<<<........>>>>>))<<<.<<..<..<....<<<<<<<<<....<
<<<..<<<..<<<<<.<<<<<<...((((...>>>>>><<..<<<<...<
<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>...>>>>...>>..
..<<.........>>.....>>>>>...>>>...>>>>.........>>>
>>>.>>>...>..>..>>.>>>>>>>..>>.....<<......>>>>>>>
.<<<<.....>>>>..>>>>..<<<<<...<<<<<<<<.<<.........
<.....<<<<<.....<..>......>>>>>.<<<..<<<<<<<.....<
......>.....>>>>>>>..>>>.............<<<<<<<<<..<<
<.........>>>..<<<<<<<.....<<<....>>>.......>>>>>>
>.<<<<<.<<<..<<<<<<<..<<<...<<...<<<<<..<<....>>..
.>>>>>...>>...>>>>>>>>..>>>>><<<<<<.......>>>>>>..
......<...........<<<<<<.....>>>>>>.....>....>>>>>
..>>.>>>>>>>..>..>>.>>>>>>>>>>>>>>>.....>.((..<<<<
<......))>>>>>..<<<<<<<<.(((.[[......<<<<<<<<<<..<
<<<<.<<<.<<<<<.<<<<<<<<<<<<<<........>>>>>>>>>>>>>
>...<<.<<<<<<<.....>>>>>>>>>....>>>>>.>>>..>>>>>..
<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<
...<<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>>..
.<<<<..<<<<....>>>>..>>>>.<<<....>>>.>>)))]......<
<<<<<<.((..>>>>..))>>>>>>>.............>>>>..>>>>>
>.......<<<<.<.<.<<<<<..<<.......>>>..>>>>.>...>>>
>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>
.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<.
...>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..
<<<<<<<...............>>>>>>>.<<<<<...<<<<..<<<<<<
<<<<<<))))>>>>>>..>>>>>>..>>>>.>>>>>..<<<<....<<<<
<...........>>>>>....>>>>>>>>.......>>>>>>>..<<<<<
....>>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<<
....<<<<<....>>>>>...>>...>>>>>.>>>...>>>>......>>
>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9c4g Mechanistic basis for the translation inhibition of Cutibacterium acnes by Clindamycin.
Resolution2.53 Å
Binding residue
(original residue number in PDB)		L5 H6 K9 P10 A11 G13 A14 H15 K16 K18 T19 R20 V21 G22 R23 G24 G26 K28 G29 K30 T31 A32 G33 R34 G35 T36 K37 G38 T39 R42 K43 V45 F48 F49 A50 G51 G52 Q53 M54 M58 Q59 A60 P61 K62 G64 G65 F66 H67 N68 P69 F70 R71 Q75 V76 N78 K81 R104 K110 L112 G113 T114 S129 K130 S131
Binding residue
(residue number reindexed from 1)		L4 H5 K8 P9 A10 G12 A13 H14 K15 K17 T18 R19 V20 G21 R22 G23 G25 K27 G28 K29 T30 A31 G32 R33 G34 T35 K36 G37 T38 R41 K42 V44 F47 F48 A49 G50 G51 Q52 M53 M57 Q58 A59 P60 K61 G63 G64 F65 H66 N67 P68 F69 R70 Q74 V75 N77 K80 R103 K109 L111 G112 T113 S128 K129 S130
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