Structure of PDB 7p48 Chain k Binding Site BS01

Receptor Information
>7p48 Chain k (length=114) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NIENGVAHIRSTFNNTIVTITDEFGNALSWSSAGALGFKGSKKSTPFAAQ
MASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQSAGLEVTAIRDVT
PVPHNGCRPPKRRR
Ligand information
>7p48 Chain a (length=1479) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacggacugauguuagcggcggacgggugaguaac
acguggauaaccuaccuauaagacugggauaacuucgggaaaccggagcu
aauaccggauaauauuuugacgcaugguucaaaagugaaagacggcuguc
acuuauagauggauccgcgcugcauuagcuaguugguaagguaacggcuu
accaaggcaacgaugcauagccgaccugagagggugaucggccacacugg
aacugagacacgguccagacuccuacgggaggcagcaguagggaaucuuc
cgcaaugggcgaaagccugacggagcaacgccgcgugagugaugaagguc
uucggaucguaaaacucuguuauuagggaagaacauauguguaaguaacu
gugcacaucuugacgguaccuaaucagaaagccacggcuaacuacgugcc
agcagccgcgguaauacguagguggcaagcguuauccggaauuauugggc
guaaagcgcgcguaggcgguuuuuuaagucugaugugaaagcccacggcu
caaccguggagggucauuggaaacuggaaaacuugagugcagaagaggaa
aguggaauuccauguguagcggugaaaugcgcagagauauggaggaacac
caguggcgaaggcgacuuucuggucuguaacugacgcugaugugcgaaag
cguggggaucaaacaggauuagauacccugguaguccacgccguaaacga
ugagugcuaaguguuaggggggccccuuagugcugcagcuaacgcauuaa
gcacuccgccuggggaguacgaccgcaagguugaaacucaaaggaauuga
cggggacccgcacaagcgguggagcaugugguuuaauucgaagcaacgcg
aagaaccuuaccaaaucuugacauccucuagagauagaggacagguggug
caugguugucgucagcucgugucgugagauguuggguuaagucccgcaac
gagcgcaacccuuaagcuuaguugccaucaugggcacucuaaguugacug
ccggugacaaaccggaggaagguggggaugacgucaaaucaucaugcccc
uuaugauuugggcuacacacgugcuacaauggacaauacaaagggcagcg
aaaccgcgaggucaagcaaaucccauaaaguuguucucaguucggauugu
agucugcaacucgacuacaugaagcuggaaucgcuaguaaucguagauca
gcaugcuacggugaauacguucccgggucuuguacacaccgcccgucaca
ccacgagaguuuguaacacccgaagccgguggaguaaccuaggagcuagc
cgucgaaggugggacaaaugauuggggugaagucguaacaagguagccgu
aucggaaggugcggcuggaucaccuccuu
.....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<
<.<<<..<<<..<<...<<......>>...>>>>>......<<.......
.<<<<<<<..<<...<<<<<<<.<<<<.....<<<<<<....>>>>>>..
....>>>>......<<<.<.........>.>>>.......<..<.>..>.
.>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>>>
>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<
<.<.........>>>>>>.<<<<<..>>>>>...>>>>>>.........<
<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<
....>>>>.....>>>>..<<<<<<<<.......<.<<<<<<<.......
.>>>>>>>.>........>>>>>>...>>.<<<<<(((...<<<<<....
.<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<
((.....<<<<<..<<<.<<<<<<<.<<<<<<<<<.......<<<<<<..
...>>>>>>.....>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<
<<<....<<<<<<<<...<<<......>>>......>>>>>>>>......
.....<<....>>.>>>>>>>..>>>>>.>>>...>>>..>>>>>....<
<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.........
.<<<<<<..<<<<<<<<<<<<.>>>>>>>>>>>>...<<..))>>.....
>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<
<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>
..........<<<<<<<......<<.<<<<....>>>>.>>.<<<.<<<.
.<<<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>
>>>>.....<<<..<<<<<<<..<<<..<..>>>>...>>>>>>>.....
<<<<<.....>>>>>.........>>>.........>>>...>>>>>>>>
>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<.
..<<<....>>>...>>....>>>.....>>>>>>>......<....<<<
<<<<........>>>>>>>....>.....>>>>>>....<<<<<<<....
.....>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<
<<.<<<..<<<<<<..<<<<....<.<<<<..<<<..<<..>>.>>>.>>
>>.>...>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<
<<<....>>>>>>>>>.............
Receptor-Ligand Complex Structure
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PDB7p48 Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		H22 N28 N29 T33 G39 N40 A41 W44 G48 A49 P117 H118 N119 C121 R122 K125 R127 R128
Binding residue
(residue number reindexed from 1)		H8 N14 N15 T19 G25 N26 A27 W30 G34 A35 P103 H104 N105 C107 R108 K111 R113 R114
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7p48, PDBe:7p48, PDBj:7p48
PDBsum7p48
PubMed35137182
UniProtA0A077UKD6

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