Structure of PDB 7m4w Chain k Binding Site BS01

Receptor Information
>7m4w Chain k (length=117) Species: 480119 (Acinetobacter baumannii AB0057) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRTVSEGVAHIHASFNNTIVTITDRQGNALAWATSGGQGFRGSRKSTPFA
AQVAAEVAGKAALDYGLKNLDVLVKGPGPGRESAVRALGAVGYKINSITD
VTPIPHNGCRPPKKRRV
Ligand information
>7m4w Chain a (length=1528) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaacugaagaguuugaucauggcucagauugaacgcuggcggcaggcuua
acacaugcaagucgagcgggggaagguagcuugcuaccggaccuagcggc
ggacgggugaguaaugcuuaggaaucugccuauuagugggggacaacauc
ucgaaagggaugcuaauaccgcauacguccuacgggagaaagcaggggau
cuucggaccuugcgcuaauagaugagccuaagucggauuagcuaguuggu
gggguaaaggccuaccaaggcgacgaucuguagcgggucugagaggauga
uccgccacacugggacugagacacggcccagacuccuacgggaggcagca
guggggaauauuggacaauggggggaacccugauccagccaugccgcgug
ugugaagaaggccuuaugguuguaaagcacuuuaagcgaggaggaggcua
cucuaguuaauaccuagggauaguggacguuacucgcagaauaagcaccg
gcuaacucugugccagcagccgcgguaauacagagggugcgagcguuaau
cggauuuacugggcguaaagcgugcguaggcggcuuauuaagucggaugu
gaaauccccgagcuuaacuugggaauugcauucgauacuggugagcuaga
guaugggagaggaugguagaauuccagguguagcggugaaaugcguagag
aucuggaggaauaccgauggcgaaggcagccaucuggccuaauacugacg
cugagguacgaaagcauggggagcaaacaggauuagauacccugguaguc
caugccguaaacgaugucuacuagccguuggggccuuugaggcuuuagug
gcgcagcuaacgcgauaaguagaccgccuggggaguacggucgcaagacu
aaaacucaaaugaauugacgggggcccgcacaagcgguggagcauguggu
uuaauucgaugcaacgcgaagaaccuuaccuggccuugacauacuagaaa
cuuuucagagauggauuggugccuucgggaaccuagauacaggugcugca
uggcugucgucagcucgugucgugagauguuggguuaagucccgcaacga
gcgcaacccuuuuccuuacuugccagcauuucggaugggaacuuuaagga
uacugccagugacaaacuggaggaaggcggggacgacgucaagucaucau
ggcccuuacggccagggcuacacacgugcuacaauggucgguacaaaggg
uugcuacacagcgaugugaugcuaaucucaaaaagccgaucguaguccgg
auuggagucugcaacucgacuccaugaagucggaaucgcuaguaaucgcg
gaucagaaugccgcggugaauacguucccgggccuuguacacaccgcccg
ucacaccaugggaguuuguugcaccagaaguagcuagccuaacugcaaag
agggcgguuaccacgguguggccgaugacuggggugaagucguaacaagg
uagccguaggggaaccugcggcuggauc
........<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<....
.<<<.<<<..<<<..<<.<<<...<<<<<<..>>>>>>...>>>.>>>>>
......<<.......<<<<<<<..<<...<<<<<<<<<.<<.....<<<<
<......>>>>>......>>.>.....<<<....>>>....<<<<<<..<
<....>>>>>>>>>>>>>>>>..>>.>>>>>>><<<....<<<..<<<<<
<<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>..
.>>>>.>>.<<<<<.<.........>>>>>>.<<<<<..>>>>>...>>>
>>>.........<<<...<<<<<....>>>>.>>>>..>>.>>>>>>..<
<<<......<<<<....>>>>.....>>>>...<.<<<<<......<<<<
<<<<<<.......>>>>>>.>>>>........>>>>>....>..<<<<<(
((...<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>
>..........<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<
......<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>>...<
<<<<<<<...<<<<<<<....<<<<<<<<...<<<......>>>......
>>>>>>>>...........<<....>>.>>>>>>>..>>>.>>>>>...>
>>...>>>>....<<<<<<...<<...<<<<.........>>>>...>>>
>>>>>..........<<<<<<..<<<<<<<<<<<<<...>>>>>>>>>>>
>>...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>
....>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<
......<<........>>..........<<<<<<<......<<<<<<...
<..<<<<....>>>>..>...<<....>>...>>>>.>>.<<<.<<<..<
<<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>
>>.....<<<<.<<<<<<....<<..<<<.....>>>>>.....>>>>>>
.....<<<<<.....>>>>>........>>>>.........>>>...>>>
>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<
..<<..<<<<....>>>>..>>....>>>.....>>>>>>>......<..
..<<<<<<<........>>>>>>>....>.....>>>>>>....<<<<<<
<.........>>>>>>>......>>...>>>>>>>>>>.>>....<..<<
.<.<<<<.<<<..<<<.<<<<<<<<....<<<<<<.<<<<..<<....>>
.>>>>>>>>>>...>>>>>>>>.>>>..>>>.>>>>..>.>>...>....
.<<<<<<<<<....>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB7m4w Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		N27 N28 T32 G38 N39 A40 W43 T45 G48 S54 K56 I115 H117 N118 C120 R121 K124 R126 R127
Binding residue
(residue number reindexed from 1)		N16 N17 T21 G27 N28 A29 W32 T34 G37 S43 K45 I104 H106 N107 C109 R110 K113 R115 R116
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7m4w, PDBe:7m4w, PDBj:7m4w
PDBsum7m4w
PubMed34044590
UniProtA0A4R0F9S8

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