Structure of PDB 6zce Chain k Binding Site BS01

Receptor Information
>6zce Chain k (length=579) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNSRIAIVSADKCKPKKCRQECKRSCPVVKTGKLCIEVTPTSKIAFISEI
LCIGCGICVKKCPFDAIQIINLPTNLEAHVTHRYSANSFKLHRLPTPRPG
QVLGLVGTNGIGKSTALKILAGKQKPNLGRFDDPPEWQEIIKYFRGSELQ
NYFTKMLEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRMEKSPEDVK
RYIKILQLENVLKRDIEKLSGGELQRFAIGMSCVQEADVYMFDEPSSYLD
VKQRLNAAQIIRSLLAPTKYVICVEHDLSVLDYLSDFVCIIYGVPSVYGV
VTLPASVREGINIFLDGHIPAENLRFRTFSYPSLKKTQGDFVLNVEEGEF
SDSEILVMMGENGTGKTTLIKLLAGALKPDEGQDIPKLNVSMKPQKIAPK
FPGTVRQLFFKKIRGQFLNPQFQTDVVKPLRIDDIIDQEVQHLSGGELQR
VAIVLALGIPADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVE
HDFIMATYLADKVIVFEGIPSKNAHARAPESLLTGCNRFLKNLNVTFRRD
PNSFRPRINKLDSQMDKEQKSSGNYFFLD
Ligand information
>6zce Chain A (length=1719) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuacaugguauaacuguggu
aauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagagaugu
auuuauuagauaaaaaaucaagaugauucauaauaacuuuucgaaucgca
uggccuugugcuggcgaugguucauucaaauuucugcccuaucaacuuuc
gaugguaggauaguggccuaccaugguuucaacggguaacggggaauaag
gguucgauuccggagagggagccugagaaacggcuaccacauccaaggaa
ggcagcaggcgcgcaaauuacccaauccuaauucagggagguagugacaa
uaaauaacgauacagggcccauucgggucuuguaauuggaaugaguacaa
uguaaauaccuuaacgaggaacaauuggagggcaagucuggugccagcag
ccgcgguaauuccagcuccaauagcguauauuaaaguuguugcaguuaaa
aagcucguaguugaacuuugggcccgguuggccgguccgaucguguacug
gauuuccaacggggccuuuccuucggacuuuuacuuugaaaaaauuagag
uguucaaagcaggcguauugcucgaauauauuagcauggaauaauagaau
aggacguuugguucuauuuuguugguuucuaggaccaucguaaugauuaa
uagggacggucgggggcaucaguauucaauugucagaggugaaauucuug
gauuuauugaagacuaacuacugcgaaagcauuugccaaggacguuuuca
uuaaucaagaacgaaaguuaggggaucgaagaugaucagauaccgucgua
gucuuaaccauaaacuaugccgacuagggaucgggugguguuuuuuuaau
gacccacucggcaccuuacgagaaaucaaagucuuuggguucugggggga
guauggucgcaaggcugaaacuuaaaggaauugacggaagggcaccacca
ggaguggagccugcggcuuaauuugacucaacacggggaaacucaccagg
uccagacacaauaaggauugacagauugagagcucuuucuugauuuugug
ggugguggugcauggccguucuuaguugguggagugauuugucugcuuaa
uugcgauaacgaacgagaccuuaaccuacuaaauaguggugcuagcauuu
gcugguuauccacuucuuagagggacuaucgguuucaagccgauggaagu
uugaggcaauaacaggucugugaugcccuuagacguucugggccgcacgc
gcgcuacacugacggagccagcgagucuaaccuuggccgagaggucuugg
uaaucuugugaaacuccgucgugcuggggauagagcauuguaauuauugc
ucuucaacgaggaauuccuaguaagcgcaagucaucagcuugcguugauu
acgucccugcccuuuguacacaccgcccgucgcuaguaccgauugaaugg
cuuagugaggccucaggaucugcuuagagaucagagcggagaauuuggac
aaacuuggucauuuagaggaacuaaaagucguaacaagguuuccguaggu
gaaccugcggaaggaucau
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<.............<.....<<.<<<.
....>>>.>>......>.........<<<<<..<<....>>..>>>>><.
<.<<<<<<......(((((((.........>>>>>>.>...>...<<<<.
.<<<.....>>>.>>>>....>>>...>>>>..>>>.<<<....<<<...
.<<<<<<<<.......>>>>>>>>>>>......>>>...<<<.<<<<...
.>>>>....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.
>...>>>>>>.........<<<....<<<.....>>>..>>>..>....>
.>.....<<<<<<<<<<..........>>>>>>>.>>>......<<<.<.
..........>>.>>.........<<<<<((....<.<<<<.....<<..
))>>.......>>>>>>>>>>..>>>>>>>>>>.........<<<[[...
..<.<<...<<<.<<....<<<<<<.<<<<<<<<<<.<<..>>...>>>>
>....>>>>>.>>>>>>....<<..>>...<<<<<.<<.......<<...
<.......>..<<<.....>>>....>>......>>.>>..>>>......
...<<...<<<<<<<<.....))))))).>>>>>>>>..>>.....>>..
..<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>...
...>.>>>>>>..>>.......<<....>>...>>>>...>>>>>.>>>.
..>>>...>>.>....<<<<<<<...<...<<<<.<.....>.>>>>...
>>>>>>>>..........<<<.<<.<<<..<<<<<<<<.<<<........
>>>>>>>>>>>..>>>...<<..]]>>...>>.....>>>.>>>.<<<..
....<<<<....>>>>....>>>..]]]].}<<<<<.<<<<<<<..<<.<
<<<<<..<<<.<<<<<<......<<........>>..........<<<<<
.<....<<<<<........<<.<<<........>>>.>>......>>>>>
.<.<<.<<<..<<.<<<<<<....<<<.<<<<<....>>>...<<<....
..>>>...>>.>>>....<<<<<.<<..<<<<..<<<<<.<<<<<<....
>>>>>>...>>>>>..>>>>.>>....<<<<<<.....>>>>>>......
.>>>>>....>>>.>>>.....>>>>>>>>....>.>>>>>...>>.>>>
>.>>>.....<<<<<<<......<<.....<<..<<<<....>>>>..>>
....>>.......>>>>>>>......<....<<<<<<..........>>>
>>>....>.....>>>>>>....<<<<<<<<.......>>>>>>>>....
..>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<
<<.<<<..<.<<......<<<<<<<.<<..>>.>>>>>>>......>>.>
..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<.
...>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zce A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Resolution5.3 Å
Binding residue
(original residue number in PDB)		G149 S150 L306 R311 E312 A324 E325 N326 K585 S588
Binding residue
(residue number reindexed from 1)		G146 S147 L303 R308 E309 A321 E322 N323 K560 S563
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0000054 ribosomal subunit export from nucleus
GO:0006364 rRNA processing
GO:0006412 translation
GO:0006413 translational initiation
GO:0006415 translational termination
GO:0032790 ribosome disassembly
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:0045727 positive regulation of translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005852 eukaryotic translation initiation factor 3 complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zce, PDBe:6zce, PDBj:6zce
PDBsum6zce
PubMed33289941
UniProtQ03195|RLI1_YEAST Translation initiation factor RLI1 (Gene Name=RLI1)

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