Structure of PDB 6s13 Chain k Binding Site BS01

Receptor Information
>6s13 Chain k (length=114) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NIENGVAHIRSTFNNTIVTITDEFGNALSWSSAGALGFKGSKKSTPFAAQ
MASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQSAGLEVTAIRDVT
PVPHNGCRPPKRRR
Ligand information
>6s13 Chain a (length=1539) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcgg
cggacgggugaguaacacguggauaaccuaccuauaagacugggauaacu
ucgggaaaccggagcuaauaccggauaauauuuugaaccgcaugguucaa
aagugaaagacggucuugcugucacuuauagauggauccgcgcugcauua
gcuaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccu
gagagggugaucggccacacuggaacugagacacgguccagacuccuacg
ggaggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagca
acgccgcgugagugaugaaggucuucggaucguaaaacucuguuauuagg
gaagaacauauguguaaguaacugugcacaucuugacgguaccuaaucag
aaagccacggcuaacuacgugccagcagccgcgguaauacguagguggca
agcguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaa
gucugaugugaaagcccacggcucaaccguggagggucauuggaaacugg
aaaacuugagugcagaagaggaaaguggaauuccauguguagcggugaaa
ugcgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucug
uaacugacgcugaugugcgaaagcguggggaucaaacaggauuagauacc
cugguaguccacgccguaaacgaugagugcuaaguguuaggggguuuccg
ccccuuagugcugcagcuaacgcauuaagcacuccgccuggggaguacga
ccgcaagguugaaacucaaaggaauugacggggacccgcacaagcggugg
agcaugugguuuaauucgaagcaacgcgaagaaccuuaccaaaucuugac
auccuuugacaacucuagagauagagccuuccccuucgggggacaaagug
acagguggugcaugguugucgucagcucgugucgugagauguuggguuaa
gucccgcaacgagcgcaacccuuaagcuuaguugccaucauuaaguuggg
cacucuaaguugacugccggugacaaaccggaggaagguggggaugacgu
caaaucaucaugccccuuaugauuugggcuacacacgugcuacaauggac
aauacaaagggcagcgaaaccgcgaggucaagcaaaucccauaaaguugu
ucucaguucggauuguagucugcaacucgacuacaugaagcuggaaucgc
uaguaaucguagaucagcaugcuacggugaauacguucccgggucuugua
cacaccgcccgucacaccacgagaguuuguaacacccgaagccgguggag
uaaccuuuuaggagcuagccgucgaaggugggacaaaugauuggggugaa
gucguaacaagguagccguaucggaaggugcggcuggau
...........<.<<<<......<<<..<<<<.<..<<<<<<<.....<<
<.<<....<<..<<..<<<......................>>>..>>>>
.......<<........<<<<<<...<<...<<<<..<..........<<
..<<....>>..>>....................................
........................>..>>>>..>>.>>>>>>.<<<....
<<<....<<<<<<.......>>>>>>..>>>......>>>..<<<<<<<.
.....>>...>>>>>.>>.<<<<<.<.........>>>>>>.<<<<....
>>>>....>>>>>.........<<<....<<<<....>>>>..>>>..>>
.>>>>>..........................................<<
...........<<<<<........>>>>>............>>.......
......<.((.....<<<<.....<<..))>>.......>>>>..>....
>.>>>>.>>>..........<<<((.....<<<....<<<.<<<<<<..<
<....<<<.......<<<<<<.....>>>>>>.....>>>......>>.>
>>>>>...<<..<.<<....<.<<<<...............<<.......
.>>.........................<<....>>.>>>>>....>>.>
...>>...>>>....>>>....<..<<.........<<<..........>
.>>......>>..>..........<<<<<<..<<..<<<<<<<<......
>>>>>>>>..>>...<...)).>.....>>>>>>.>>>..<<.......<
<<....>>>.....>>...>>>>.>.<....<<<<<<<.....<<<<<..
<<<<<...........<<........>>..........<<<<<<<.....
.<<<<.......<<<<<....>>>>>.....<<.....>>......>>.>
>..<<.<<<...<<<.........<<<<<.<<<....>>>...<<<....
..>>>....>>>>>......<<..<....<........<<......>>..
.....>...>......<<<<.......>>>>.........>>........
.......>>>.>>>>>....>>>>>>>.........>>>>>.......<<
<<<.....<<<..........................>>>.....>>>>>
.............<.<..<..........>..>.>..........>>>>>
......<<<<<<.........>>>>>>............>>>>>>>....
>.............<<<<.<<.......<<..<<<<....<.<<<<..<<
..............>>.>>>>>....>>>>..>>.......>>.>>>>..
.............<<<<<............>>>>>....
Receptor-Ligand Complex Structure
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PDB6s13 Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Resolution3.58 Å
Binding residue
(original residue number in PDB)		H22 R24 T33 G39 A41 L42 S43 W44 G48 A49 G51 F52 K53 G54 S55 K56 H118 N119 G120 C121 P123 P124 K125 R126 R128
Binding residue
(residue number reindexed from 1)		H8 R10 T19 G25 A27 L28 S29 W30 G34 A35 G37 F38 K39 G40 S41 K42 H104 N105 G106 C107 P109 P110 K111 R112 R114
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6s13, PDBe:6s13, PDBj:6s13
PDBsum6s13
PubMed31391518
UniProtA0A077UKD6

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