Structure of PDB 6om7 Chain k Binding Site BS01

Receptor Information
>6om7 Chain k (length=84) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPK
Ligand information
>6om7 Chain D (length=157) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcuu
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>.............>>>..)...>>
>....<<....>><<<<<<<<.......>>>>>>>>..............
.......
Receptor-Ligand Complex Structure
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PDB6om7 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		R20 R21 T59 T61 G62 R63 M64 R65 H66 L67 K68 Y71 R72 R73 F74 R79 E80 G81 T82
Binding residue
(residue number reindexed from 1)		R19 R20 T58 T60 G61 R62 M63 R64 H65 L66 K67 Y70 R71 R72 F73 R78 E79 G80 T81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6om7, PDBe:6om7, PDBj:6om7
PDBsum6om7
PubMed31160784
UniProtP61927|RL37_HUMAN Large ribosomal subunit protein eL37 (Gene Name=RPL37)

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