Structure of PDB 6olf Chain k Binding Site BS01

Receptor Information
>6olf Chain k (length=84) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPK
Ligand information
>6olf Chain D (length=157) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcuu
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>.............>>>..)...>>
>....<<....>><<<<<<<<.......>>>>>>>>..............
.......
Receptor-Ligand Complex Structure
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PDB6olf Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		R20 T59 G62 R63 R65 H66 K68 R72 R73 F74 H76 R79 G81 T82 T83 P84
Binding residue
(residue number reindexed from 1)		R19 T58 G61 R62 R64 H65 K67 R71 R72 F73 H75 R78 G80 T81 T82 P83
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6olf, PDBe:6olf, PDBj:6olf
PDBsum6olf
PubMed31160784
UniProtP61927|RL37_HUMAN Large ribosomal subunit protein eL37 (Gene Name=RPL37)

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