Structure of PDB 6gsm Chain k Binding Site BS01

Receptor Information
>6gsm Chain k (length=414) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIK
LGYANAKIYKCQEFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDIL
MSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNK
VDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVK
TIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLG
DEIEIRPGIVTDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTK
VDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKKQAKVRK
LEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRI
EKHWRLIGWATIKK
Ligand information
>6gsm Chain 1 (length=74) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcgccguggcgcaguggaagcgcgcagggcucauaacccugauguccuc
ggaucgaaaccgagcggcgcuacc
<<<<<<<..<<<<.......>>>>.<<<<<.......>>>>>.......<
<<.......>>>..>>>>>>>...
Receptor-Ligand Complex Structure
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PDB6gsm Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Resolution5.15 Å
Binding residue
(original residue number in PDB)		K129 F321 K325 P326 A409
Binding residue
(residue number reindexed from 1)		K40 F221 K225 P226 A308
Enzymatic activity
Enzyme Commision number 3.6.5.3: protein-synthesizing GTPase.
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:6gsm, PDBe:6gsm, PDBj:6gsm
PDBsum6gsm
PubMed34648019
UniProtP32481|IF2G_YEAST Eukaryotic translation initiation factor 2 subunit gamma (Gene Name=GCD11)

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