Structure of PDB 3jb9 Chain k Binding Site BS01

Receptor Information

>3jb9 Chain k (length=89) Species: 284812 (Schizosaccharomyces pombe 972h-)

TLYVNNLNDKINKNDLRTALYMLFSTYGTVVDIVALKTPKMRGQAHVVFF
DPSAAAIAMKALKNFIFFGKEMKIQYAHSKSKIIERIVA

Ligand information

>3jb9 Chain P (length=111)

auucucucuuugccuuuuggcuuagaucaaguguaguaucuguaucuugu
uuuugguuuuuggaaagccucugggcuaugcuuuccucuugcuauugcac
uacuggcaagc

..................................................
.............<<<<<.<.......>.>>>>>...<<<<<<.......
....>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3jb9 Structure of a yeast spliceosome at 3.6-angstrom resolution
• Resolution: 3.6 Å
• Binding residue (original residue number in PDB): Y7 N9 N10 D13 K14 K17 V38 A39 L40 K41 K44 M45 R46 Q48 H50 K74 Q79 A81 H82 S83 K84 S85 K86
• Binding residue (residue number reindexed from 1): Y3 N5 N6 D9 K10 K13 V34 A35 L36 K37 K40 M41 R42 Q44 H46 K70 Q75 A77 H78 S79 K80 S81 K82

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0030620 U2 snRNA binding

Biological Process

• GO:0006397 mRNA processing
• GO:0008380 RNA splicing
• GO:0045292 mRNA cis splicing, via spliceosome

Cellular Component

• GO:0005634 nucleus
• GO:0005681 spliceosomal complex
• GO:0005686 U2 snRNP
• GO:0005829 cytosol
• GO:0071004 U2-type prespliceosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:3jb9, PDBe:3jb9, PDBj:3jb9
• PDBsum: 3jb9
• PubMed: 26292707
• UniProt: Q7LL14|RU2B_SCHPO Probable U2 small nuclear ribonucleoprotein B'' (Gene Name=msl1)