Structure of PDB 6tf9 Chain jP1 Binding Site BS01

Receptor Information
>6tf9 Chain jP1 (length=371) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKD
SYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEH
PVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGI
VMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFT
TTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIG
NERFRCPEALFQPSFLGMESCGIHETTYNSIMKCDVDIRKDLYANTVLSG
GTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLST
FQQMWISKQEYDESGPSIVHR
Ligand information
>6tf9 Chain FP1 (length=18) Species: 8355 (Xenopus laevis) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAAAAAAAA
Receptor-Ligand Complex Structure
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PDB6tf9 Insights into the assembly and activation of the microtubule nucleator gamma-TuRC.
Resolution4.8 Å
Binding residue
(original residue number in PDB)
Y143 R147
Binding residue
(residue number reindexed from 1)
Y142 R146
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0015629 actin cytoskeleton
GO:0097433 dense body

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:6tf9, PDBe:6tf9, PDBj:6tf9
PDBsum6tf9
PubMed31856152
UniProtO93400|ACTB_XENLA Actin, cytoplasmic 1 (Gene Name=actb)

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