Structure of PDB 8s8e Chain j Binding Site BS01

Receptor Information
>8s8e Chain j (length=267) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELS
RRRIRSIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKY
QKSKTVHSILRYCAEKFQIPLEELYKTIAWPLSRKFGHAYEAFKLSIIDE
TVWEGIEPPSKDVLDELKNYISKRLTPAVKIRADVEVSCFSYEGIDAIKD
ALKSAEDMSTEQMQVKVKLVAAPLYVLTTQALDKQKGIEQLESAIEKITE
VITKYGGVCNITMPPKA
Ligand information
>8s8e Chain 1 (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcgccguggcgcaguggaagcgcgcagggcucauaacccugauguccuc
ggaucgaaaccgagcggcgcuacca
<<<<<<<..<<<<.......>>>>.<<<<<.......>>>>>.....<<<
<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB8s8e Structural basis of AUC codon discrimination during translation initiation in yeast.
Resolution3.85 Å
Binding residue
(original residue number in PDB)
R57 S58 Q60 R64 S110 R113 Y114 K118 Y172 K175 R185 V223 L227
Binding residue
(residue number reindexed from 1)
R55 S56 Q58 R62 S108 R111 Y112 K116 Y170 K173 R182 V220 L224
External links
PDB RCSB:8s8e, PDBe:8s8e, PDBj:8s8e
PDBsum8s8e
PubMed39193907
UniProtP20459|IF2A_YEAST Eukaryotic translation initiation factor 2 subunit alpha (Gene Name=SUI2)

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