Structure of PDB 8fto Chain j Binding Site BS01

Receptor Information
>8fto Chain j (length=123) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRG
KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIF
GPVTRELRSEKFMKIISLAPEVL
Ligand information
>8fto Chain A (length=1519) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauugaagaguuugaucauggcucagauugaacgcuggcggcaggccuaa
cacaugcaagucgaacgguaacaggaagaagcuugcuucuuugcugacga
guggcggacgggugaguaaugucugggaaacugccugauggagggggaua
acuacuggaaacgguagcuaauaccgcauaacgucgcaagaccaaagagg
gggccucuugccaucggaugugcccagaugggauuagcuaguaggugggg
uaacggcucaccuaggcgacgaucccuagcuggucugagaggaugaccag
ccacacuggaacugagacacgguccagacuccuacgggaggcagcagugg
ggaauauugcacaaugggcgcaagccugaugcagccaugccgcguguaug
aagaaggccuucggguuguaaaguacuuucagcggggaggaagggaguaa
aguuaauaccuuugcucauugacguuacccgcagaagaagcaccggcuaa
cuccgugccagcagccgcgguaauacggagggugcaagcguuaaucggaa
uuacugggcguaaagcgcacgcaggcgguuuguuaagucagaugugaaau
ccccgggcucaaccugggaacugcaucugauacuggcaagcuugagucuc
guagagggggguagaauuccagguguagcggugaaaugcguagagaucug
gaggaauaccgguggcgaaggcggcccccuggacgaagacugacgcucag
gugcgaaagcguggggagcaaacaggauuagauacccugguaguccacgc
cguaaacgaugucgacuuggagguugugccggcguggcuuccggagcuaa
cgcguuaagucgaccgccuggggaguacggccgcaagguuaaaacucaaa
ugaauugacgggggcccgcacaagcgguggagcaugugguuuaauucgau
gcaacgcgaagaaccuuaccuggucuugacauccacggaaguuuucagag
augagaaugugccuucgggaaccgugagacaggugcugcauggcugucgu
cagcucguguugugaaauguuggguuaagucccgcaacgagcgcaacccu
uauccuuuguugccagcgguccggccgggaacucaaaggagacugccagu
gauaaacuggaggaagguggggaugacgucaagucaucauggcccuuacg
accagggcuacacacgugcuacaauggcgcauacaaagagaagcgaccuc
gcgagagcaagcggaccucauaaagugcgucguaguccggauuggagucu
gcaacucgacuccaugaagucggaaucgcuaguaaucguggaucagaaug
ccacggugaauacguucccgggccuuguacacaccgcccgucacaccaug
ggaguggguugcaaaagaaguagguagcuuaaccuucgggagggcgcuua
ccacuuugugauucaugacuggggugaagucguaacaagguaaccguagg
ggaaccugcgguuggauca
.......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....
<<<.<<<..<<<..<<.<<..<<<<<<<<<......>>>>>>.>>>>>..
>>>>>......<<.......<<<<<<<..<<...<<<<<<<.<.<<....
.<<<<<......>>>>>......>>.>.....<<<....>>>....<<<<
<<.>>>>>>.>>>>>>>..>>.>>>>>>><<<....<<<..<<<<<<<..
.......>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>
>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>.
........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<.
......<<<....>>>......>>>>...<.<<<<<......<.<<<<<<
<<.......>>>>>>>>.>........>>>>>....>..<<<<<(((...
<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>>....
......<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<.....
.<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<
<<...<<<<<<<....<<<<<<<<...<<<......>>>......>>>>>
>>>...........<<....>>.>>>>>>>..>>>.>>>>>...>>>...
>>>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>
..........<<<<<<.<<<<<<<<<<<<..>>>>>>>>>>>>..<<..)
)>>.....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)
))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<..
......>>..........<<<<<<<......<<<<<<<..<<<<<<<...
.>>>>>>>...<......>..>>>>>.>>.<<<.<<<..<<<<<<.....
..<<<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<
<.<<<<<<<...<<..<<<.....>>>>>....>>>>>>>.....<<<<<
.....>>>>>........>>>>.........>>>...>>>>>>>>>...>
>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<...<<<
....>>>...>>....>>>.....>>>>>>>......<....<<<<<<<.
.......>>>>>>>....>.....>>>>>>....<<<<<<<.........
>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<
<..<<<<<<<<<<<<....<<<<<<.<<<<..<<....>>.>>>>>>>>>
>...>>>>>>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<
....>>>>>>>>>......
Receptor-Ligand Complex Structure
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PDB8fto Interactions between terminal ribosomal RNA helices stabilize the E. coli large ribosomal subunit.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		P48 R49 R98
Binding residue
(residue number reindexed from 1)		P48 R49 R98
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
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Cellular Component
External links
PDB RCSB:8fto, PDBe:8fto, PDBj:8fto
PDBsum8fto
PubMed37419664
UniProtP0ADY3|RL14_ECOLI Large ribosomal subunit protein uL14 (Gene Name=rplN)

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