Structure of PDB 8etj Chain j Binding Site BS01

Receptor Information
>8etj Chain j (length=71) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSHTICRRCGKRSFHIQKSTCACCGYPAAKTRSYNWGAKAKRRRTTGTGR
MSYLKKVHRSFKNGFRSGKPA
Ligand information
>8etj Chain 1 (length=1817) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucaaaucagguaggacuacgcgcugaacaauaagcgcaggaaaa
gaaaauaaccaugauucccucaguaacggugaagcgggaaaagcucaaau
uugaaaucuggcaacauuucuuuuguuguccgaguuguaauuucaagaag
cugcuuugaguguagacgaucggucuaaguuccuuggaacaggacgucag
agagggugagaaccccgucuuuggucgauuggauaugccauauaaagcgc
uuucgaagagucgaguuguuugcagcucuaaaugggugguaaauuucauc
uaaagcuaaauauuggcgagagaccgauagcgaacaaguagagugaucga
aagaugaaaagaacuuugaaaagagaguuaaauaguacgugaaauugcug
aaagggaagcauuggaaaucaggucagcaucaguuuucgggggcggaaaa
agaauaagggaagguggcuuuccgggaguguuuauagcccuuguuguaau
acguccacuggggacugaggacugcggcuucgugccaaggaugcugacau
aaugguuuucaauggcccgucuacacggaccaaggagucuagcaucuaug
cgaguguuugggugaugaaaacccauccgcgaaaugaaagugaaugcagg
ugggaacgcccuuguggcgugcaccaucgaccgacccggaaguauggaag
gguuugaguaagagcauagcuguugggacccgaaagauggugaaccaucu
aguagcugguuccugccgaaguuucccucaggauagcagaaacucagauc
aguuuuaugaguauguaaaaugagaguuucuagugggccauuuuugguaa
gcagaacuggcgaugcgggaugaaccgaacgugagguuaaggugccggaa
uguacgcucaucagaagaaaagguguuaguucaucuagacagcaggacgg
uggccauggaagucggaauccgcuaaggaguguguaacaacucaccugcc
gaaugaacuagcccugaaaauggauggcgcuuaagcguacuacccauacc
ucaccgucuggguugaagcucagacgaguaggcaggcguggagguuugug
acgaagccuugggcgugagccugggucgaacagccucuagugcagaucuu
gguggaaguagcauucaaaugagaacuuugaagacugaaguggggaaagg
uuccaugugaacagcaguuggacauggguuccaaggugaacagccucuag
uugauagaacaauguagauaagggaagucggcaaaaugccacugucccua
ucuacuaucuagcgaaaccacagccuggggaacgggccaggcaaaaucag
cggggcuuguggcagucaagcggcgacauugcuuuccuaucauaccgaag
cagaauucgguaagcguuggacccacuaauagggacuacugaugaagugu
cgucgcaaugguaauucaacuuaguacgagaggaaccguugauucagauc
auugguauuugcggcugccugacaaggcaaugccgcggagcuaucaucug
cuggauaacggcugaacgccucuaagccagaauccgugccagaaagcgac
gauuuuuugguccgcaugauuuauauguauaaaaauagagguaggcuacu
cuccuguaucguagaagaugggcgaugguugaugaaacggaaguguuuua
uugacuuguccaugaaauuccaaucuugugcggaaucgaauccauugcau
acgacuuuaauguggaacgggguauuguaagcagcugcugagauuaagcc
uuuguucccaagauuug
.........................<<<<<........>>>>>.......
....<<....>>..<<<<<......<<.>>.....>>>>>..<<<..<..
......<<.<<<<<<<.......>>>>>>>.>>........>....<<<<
<.<<<<<..<<<<<...<<<<<<<<.....<<<<......>>>>.((...
...<<<.....))>>>......>>>>>>>>...>>>>>.....>>>>>>>
>.>>........<<<<<<<..>>>>>>>.....<<<<<<......>>>>>
>..>>>..................................<<....>>..
.............<<<<....>>>>.........................
.........<<<<<<<<<<<<.<<<<<<<.<<<<<<<<<<<<<<<.....
...<<<<<<<......<.<<<<..>>>>..>......>>>>>>>......
.>>>>>.>>>>>>>>>>........<<<.....>>>.....>>>>>>>..
..>>>>>>>>>>>>..<<<<....>>>><<<<<<....<<<<<<.<<<<<
<..<<<..<<<<<.......>>>>>..>>>...<<....>>.......<<
<<<..<<<<<.....>>>>>...>>>>>.<<<<<<<<....<<>>....>
>>.>>>.>>....>>>>>>.>>>>>>..<<.<...<<<<<<..>>>>>>.
.....>.>>..<<<<<<.......<<....>>...<<<<<<<<<<...<<
<.<<<<<<<....>>>>>>>>>>>>>>>>>>.>>..<<<<.<<.<<....
.>>.>>.>>>>....<<<......>>>...<<<<<<<...<<<(((....
.<<<<<<.....<<......<<<.<<<<<<<<<<.......<<<<<.<<.
...<<.........>>....>>.........<<......>>...>>>>>.
..>>>>>>>>>>>>>..........))).>>...>>>>>>.>>>...>>>
>>>><<<<<<<<<....>>>>>>>>>....>>>>>>..<<<<<<<<.<<.
.....<<<<.<<<<....>>>>>>>>...>>>>>>>>>>........>>>
>>><<.....<<.<<<<<<.......>>>>>><<<<<....<<<......
..<<<<<....<<.....>>..>>>>>..>>>.<<<<.....>>>>.>>>
>>..<<<<.....<<<<<<<.<<.........<.........>..>>.>>
>>>>>..>>>>>>....>>....<<<<<........>>>>>....<<<<<
..<.......<<<<<<...<<.>>...>>>>>><<<<<..<.<<<<<<<.
.....>>>>>>>...>.<<<..>>>.....>>>>>.>.>>>>>.....<<
<<<<<<..<<<<.<.<<<<<.................>>>>>.><<<<<.
..<<<<....<<<<<<<<<<....>>>>>..>>>>>...>>>>..>>>>>
.<<<<....<<<<...........>>>>....>>>>.>>>>....>>>>>
>>>.....<.<<<..<.<..........<<.......<<<<..<..>..>
>>>....>>........<<<<<....<<<<<<<<<<<<......>>>>>>
>>>>>>..>>>>>.............>.>..>>>.>.<<<<<.<......
.......>.....<<<<<<<<<.<<<....<<<..>>>...>>>....>>
>>.>>>>>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8etj Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		S15 H16 H28 A35 A42 K43 T44 R45 Y47 N48 W49 K52 R55 R56 R57 H71 G77 R79 S80 G81
Binding residue
(residue number reindexed from 1)		S2 H3 H15 A22 A29 K30 T31 R32 Y34 N35 W36 K39 R42 R43 R44 H58 G64 R66 S67 G68
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8etj, PDBe:8etj, PDBj:8etj
PDBsum8etj
PubMed36423630
UniProtP05733|RL37B_SCHPO Large ribosomal subunit protein eL37B (Gene Name=rpl3702)

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