Structure of PDB 7xtd Chain j Binding Site BS01

Receptor Information
>7xtd Chain j (length=466) Species: 460519 (Komagataella phaffii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLRNETTNTEEEKERLRKEIQKQLHEKIQKEGLARFNKSDAQDGNENHAV
FKRYESYVRESQIPSKVKNLRISIDPKAQTIILPICGRPVPFHINSFKNG
SKNEEGDYMYIRLNFNSPGMGSSVKKTELPYEDGDDKEFVRSLTFRSTNK
ERMSEVFKAITELKKTAVKRDQERKTMEDVVAQAQLVEFKGRPKKLENVF
VRPAPDSKRVTGTLFIHQNGIRYQSPVRSDHRVDILFSNIKHLFFQPCKE
ELMVIIHCHLKTPLMIGKKKTFDVQFYREVSDVTVGDEDELEQEQEERRR
KALLDKEFRRFAEEISEASNGLLDLETPFRELGFTGVPFRSSVLCLPTRD
CLIQLIDTPFLVVTLEEIEVAHLERVQFGLKNFDLVFVFKDFSKPVVHIN
TIPIEMLEFVKQWLTDVDIPYSEGAVNLNWGTIMKTIQADPYEFFENGGW
SFLGGGESDDEESEEE
Ligand information
>7xtd Chain N (length=112) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gtctggccatctttgtgtttggtgtgtttgggtggtggccgttttcgttg
tttttttctgtctcgtgcctggtgtcttgggtgtaatccaaaacgcgggg
gacagcgcgtac
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7xtd Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		S597 S598
Binding residue
(residue number reindexed from 1)		S122 S123
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0031491 nucleosome binding
GO:0140713 histone chaperone activity
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006368 transcription elongation by RNA polymerase II
GO:0034728 nucleosome organization
GO:0140719 constitutive heterochromatin formation
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0035101 FACT complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7xtd, PDBe:7xtd, PDBj:7xtd
PDBsum7xtd
PubMed35981082
UniProtC4QYQ8

[Back to BioLiP]