Structure of PDB 7qiz Chain j Binding Site BS01

Receptor Information

>7qiz Chain j (length=122) Species: 4081 (Solanum lycopersicum)

ARIKVHELRNKSKTELLAQLKDLKAELALLRVAKVTGGAPNKLSKIKVVR
LSIAQVLTVISQKQKAALREVYKNKKYLPLDLRPKKTRAIRKRLTKHQSS
LKTEREKKKEMYFPLRKYAIKV

Ligand information

>7qiz Chain 2 (length=3098)

gcgaccccaggucaggcgggauuacccgcugaguuuaagcauaucaauaa
gcggaggaaaagaaacuuacaaggauuccccuaguaacggcgagcgaacc
gggaacagcccagccuuagaaucgggcggcuccgucguccgaauuguagu
cuggagaagcguccucagcggcggaccgggcccaaguccccuggaagggg
gcgccggagagggugagagccccgucgugcccggacccugucgcaccacg
aggcgcugucuacgagucggguuguuugggaaugcagcccaaaucgggcg
gugaauuccguccaaggcuaaauacuggcgagagaccgauagcgaacaag
uaccgcgagggaaagaugaaaaggacuuugaaaagagagucaaagagugc
uugaaauugucgggagggaagcggaugggggccggcgaugcgccccgguc
gguguggaacggcgagccgguccgccgaucgacucggggcguggaccagc
guggauugggggggcggccaaagcccgggcucucgauacgcccguggaac
gccgucuccccgauuguggaaggcagcgcgcgccuccggcgugcuucggc
aucugcgcgcuccggacgcuggccugugggcuccccauucgacccgucuu
gaaacacggaccaaggagucugacaugugugcgagucaacgggcgaguaa
acccguaaggcguaaggaagcugauuggugggaucccccugaggggugca
ccgccgaccgaccuugaucuucugagaaggguucgagugugagcauaccu
gucgggacccgaaagauggugaacuaugccugagcggggcgaagccagag
gaaacucugguggaggcccgcagcgauacugacgugcaaaucguucgucu
gacuuggguauaggggcgaaagacuaaucgaaccgucuaguagcugguuc
ccuccgaaguuucccucaggauagcuggagcucgcgugcgaguucuaucg
gguaaagccaaugauuagaggccucggggccucgaccuauucucaaacuu
uaaauagguaggacggcgcggcugcuuuguugagccgcgccacggaauca
agagcuccaagugggccauuuuugguaagcagaacuggcgaugcgggaug
aaccggaagccggguuacggugccaaacugcgcgcuaaccuagaucccac
aaaggguguuggucgauuaagacagcagcugccgaaucaacuagccccga
aaauggauggcgcuuaagcgcgcgaccuacacccggccgucggggcaagu
gccaggccccgaugaguaggagggcgcggcggucgcugcaaaaccuuggg
cgcgagccugggcggagcggccgucggugcagaucuuggugguaguagca
aauauucaaaugagaacuuugaaggccgaagaggggaaagguuccaugug
aacggcacuugcacauggguuagucgauccuaagggucgggggaaccccg
acagauagcgcgucgcgcguacuccgaaagggaaucggguuaaaauuccu
gaaccgggacguggcgguugacggcaacguuaggaaguccggagacgucg
gcgggagccucgggaagaguuaucuuuucuguuuaacagccugcccaccc
uggaaucggcucagccggagguaggguccagcggcuggaagagcaccgca
cgugguguccggugcgcucccggcggcccuugaaaauccggaggaccgaa
ugccguccacgcccggucguacucauaaccgcaucaggucuccaagguga
acagccucuggucgauggaacaauguaggcaagggaagucggcaaaaugg
auccguaacuucgggaaaaggauuggcucugagggcuggacagccaacuc
agaacugguacggacaaggggaauccgacuguuuaauuaaaacaaagcau
ugcgauggucccaacggauguuuacgcaaugugauuucugcccagugcuc
ugaugucaaagugaagaaauucaaccaagcgcggguaaacggcgggagua
acuaugacucucuuaagguagccaaaugccucgucaucuaauuagugacg
cgcaugaauggauuaacgagauucccacugucccugucuacuauccagcg
aaaccacagccaagggaacgggcuuggcagaaucagcggggaaagaagac
ccuguugagcuugacucuaguccgacuuugugaaaugacguuauuuuacu
uauuccgugaaucggaagcggguuuuuggacccaaggcucgcuucgcggg
ccgauccgggcggaagacauugucagguggggaguuuggcuggggcggca
caucuguuaaaagauaacgcagguguccuaagaugagcucaacgagaaca
gaaaucucguguggaacagaaggguaaaagcucguuugauucugauuucc
aguacgaauacgaaccgugaaagcguggccuaacgauccuuuagaccuuc
ggaauucgaagcuagaggugucagaaaaguuaccacagggauaacuggcu
uguggcagccaagcguucauagcgacguugcuuuuugauccuucgauguc
ggcucuuccuaucauugugaagcagaauucaccaaguguuggauuguuca
cccaccaauagggaacgugagcuggguuuagaccgucgugagacagguua
guuuuacccuacugaugacagugucgcaauaguaauucaaccuaguacga
gaggaaccguugauucacacaauuggccaucgcgcuugguugaaaagcca
guggcgcgaagcuaccgugugcuggauuaugacugaacgccucuaaguca
gaauccgggcuagaagcgacgcaugcgcccgccguccggccgacccgcag
uaggggccggcccccaagggcacgugucguuggcuaagucgccgcgacgg
aagcgucgcggugaccgccuugaaguacaauuuccaucgagcggcgggua
gaauccuuugcagacgacuuaaacgcgacgggguauuguaaguggcagag
uggccgccacgauccacugagauucagcccuuugucgcuccgauucgu

........................<<<<<<.....<......>......>
>>>>.>.........<<....>>..<<<<<.......<.....>......
>>>>>..[[[..<.<......<<<<<<<<<...>>>>>>>>>......>.
>...<<<<<<<<.<<<.<<<<<<<.<<<<<<.<....<<<<......>>>
>.((......<<<.....))>>>...>.>>>>>>...>>>>>>>.....>
>>>>>>>.>>>.......<<<<<<<........>>>>>>>.....(((((
..<<<<<<)))))..]]]................................
..<<....>>...............<<<<....>>>>.............
.....................<<<<<<<<<<<<......<<<<<<<<<<<
<..<<<<<.<<<<..>>>>.>>>>>....>>>>.>>>>>>>>.<.<<<<<
<..<<<<<<<<<<<<<<<.....<<<<<<<.........>>>>>.>>...
>>>>>>>>>>>>>>>.........<<<<<<<<<<...>>>..<<....>>
....>>>>>>>.....>>>>>>.>....>>>.>>>>>>>>>..<<<<...
.....>>>><<<<<<...<<<<<<<.<<<<<<..<<<..<<<<.......
.>>>>...>>>...<<....>>....<<<<<...<<<<....>>>>....
>>>>>.<<<<<<<....<<....>>....>>.>>>.>>....>>>>>>.>
>>>>>>.<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<<<<<
....>>>>>>>.....>>>...<<<<.<<.<<........>>>>>>>>..
..>>>>>>>>>...<<.......>>......>>>>>>...>..>.>>..<
<<<<<....<.<<<....>>>.><<<<<<<<<<......<<.<<<<<<<.
....<<<....<<<..<.<<<..<<<<<..>>>>>>>>.>..>>>..>.>
>.....>>>>>...<<<<<<<<<.<......>>>>>>>>>>....>>>>.
.>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<....
..>>>...<<<<<<<...<<<(((.....<<<<<<.......<.......
...<<<.<<<<<<.<<<.......<<....>>...>>>.>>>>>>>>>..
........))).>....>>>>>>.>>>...>>>>>>><<<<<<<<<....
.....>>>>>>>>>....>>>>>><.<<<<<<<<<<.......<<<.<<<
<....>>>>>>>....>>>>>>>>>>..>.....>>>>>><<.....<<.
....<<<<<<.......>>>>>><<<<.....<<<<<.<<...<<<<<<.
..<<.....>>.>>>>>>....((<<<<<<...<<....<<<....>>>.
.......<<<<<.>>>>>.....>>....>>...<<<<<........>>>
>>))<<<<.<<<<<<<<...<<<....>>>...<...<<<<<<...<<<<
.<<<<<<<.<<<<<.<<<<.......>>>>.><...<<<<<.....<<<<
<<....<<<<...>>>>....>>>>>>.....>>>>>....><<<<<<<.
.>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>>>...>....
..>>>>.>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<..
...>>>>..>>>>..<<<<.....<<<<<<<.<<...............<
<<<<...............>>>>><<.<<<<<<<<<<<..>>>>>..>>>
>>>.>>............<<<<<<<<<..<<<.........>>>..<<<<
<<<....<<<<....>>>>......>>>>>>>...<<..<<<..<<<<<<
...<<<.....<<<<....>>>>.....>>>.>>>>..>>>>><<<<<<.
......>>>>>>........<...........<<<<<.......>>>>>.
....>.....>>....>>.>>>>>>>.....>>.>>>>>>>..>>>>>>.
...>>....<<<<<........>>>>>....[[[[[..{{{.{{......
[[[[.{{[[[[..<<<<<.<<<.<<<...<<<<<<<<<..>>>>>>>>>.
..<<<<<.....<<<<...................<<<<<<<...>>>>>
>>..>>>>..>>>>>......>>>.>>>..>>>>>...<<<.....>>>.
.<<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<...
....>>>>>>.....<<...(((>>....>>>>>>>...<<<.<<<<<..
.....>>>>.>>>>.<<<....>>>.>>))).......((((((..((((
.>>>>>>))))))))))..........]]]]..}}]]]].......<<.<
.<.<<<<<<...<<.......>>...>>>>>>...>>.>.>.......<<
<<<.<<<<<<..<<<.<<<<<......>>>>>...>>>.<<<........
.>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>.
...}}..}}}.]]]]]....<<<<<<<..<<<<...<<<<<.........
........>>>>>..<<<<<...<<<<....<<<<<<<<<......>>>>
..>>>>>...>>>>..>>>>>.<<<<...<<<<<...........>>>>>
...>>>>.>>>>...>>>>>>>....<<<<<<<<<.<<.....<<.....
..<<<<<..>>>>>....>>...........<<<...<<<<<<<<<<<..
....>>>>>>>>>>>.>>>..................>>.>>>>>>>>>.
<<<<<.<.............>...<<<<<<<<<.<<<....<<<<.<..<
<<<<.>>>>>..>>>>>...>>>....>>>>..>>>>>...>>>>>..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7qiz Specific features and methylation sites of a plant ribosome
• Resolution: 2.38 Å
• Binding residue (original residue number in PDB): K77 Y78 R84 K93 T96 K97 H98 E105 R106 K110 M112 Y113 K118
• Binding residue (residue number reindexed from 1): K76 Y77 R83 K92 T95 K96 H97 E104 R105 K109 M111 Y112 K117

Gene Ontology

Molecular Function

• GO:0003729 mRNA binding
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7qiz, PDBe:7qiz, PDBj:7qiz
• PDBsum: 7qiz
• PubMed: 35643637
• UniProt: Q53U38