Structure of PDB 7ohw Chain j Binding Site BS01

Receptor Information
>7ohw Chain j (length=71) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHTLCNRCGRRSFHVQKKTCSSCGYPAAKTRSYNWGAKAKRRHTTGTGRM
RYLKHVSRRFKNGFQTGSASK
Ligand information
>7ohw Chain 1 (length=1639) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacuuauaucaauaagc
ggaggaaaagaaaccaaccgggauugccuuaguaacgcgagugaagcggc
aaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaauuug
gagagggcaacuuuggggccguuccuugucuauguuccuuggaacaggac
gucauagagggugagaaucccguguggcgaggagugcgguucuuuguaaa
gugccuucgaagagucgaguuguuugggaaugcagcucuaaguggguggu
uccaucuaaagcuaaauauuggcgagagaccgauagcgaacaaguacagu
gauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacgugaaa
uuguugaaagggaagggcauuugaucagacaugguguuuugugcccucug
cuccuuguggguaggggaaucucgcauuucacugggccagcaucaguuuu
gguggcaggauaaauccauaggaauguagcuugccucgguaaguauuaua
gccugugggaauacugccagcugggacugaggacugcgacguaagucaag
gaugcuggcauaaugguuauaugccgcccgucuugaaacacggaccaagg
agucuaacgucuaugcgaguguuuggguguaaaacccauacgcguaauga
acgagguuggggccucgcaagaggugcacaaucgaccgauccugaggaug
gauuugguaagagcauagcuguugggacccgaaagauggugaaaaccauc
uaguagcugguuccugccgaaguuucccucaggauagcagaagcucguau
caguuuuaugaaaaugaagagcuuuuagugggccauuuuugguaagcaga
acuggcgaugcgggaugaaccgaacguagaguuaaggugccggaauacac
gcucaucagacacaaaagguguuaguucaucuagacagccggacgguggc
cauggaagucggaauccgcuaaggaguguguaacaacucaccggccgaau
gaacuagcccugaggauggcgcucaagcguguuaccuauacucuaccguc
aggguugauaugaugcccugacgaguaggcaggcguggaggucagugacg
aagccuagaccguaaggucgggucgaacggccucuagugcagaucuuggu
gguaguagcagcgaaaccacagccaaggaacgguugggcuugggcaguca
agcgcgacauugcuauaccgaagcagaauucgguaauguuaccgcaauag
uaauugaacuuaguacgagaggaacaguucauucggauaauugguuuuug
cggcugucuaucaggcauugccgcgaagcuacauccgcuggauuauggcu
gaacgccucuaagucagaauccaugcuagaacgcggugaugcuccacaca
gauggauacgaauaaggcguccuuguggcgucgcugaaccauagcaggcu
agcaacggugcacuuggcggaaaggccuugggugcuugcuggcgaauugc
aaugcguggggauaaaucauuuguauacgacuuagauguacaacggggua
uuguaagcagcugcugagauuccuuuguugucugauuug
..........................<<<<<<.....<..>......>>>
>>.>.........<<....>>..<<<<<......<<....>>.....>>>
>>..<<<..<........<<.<<<<<<...>>>>>>.>>........>..
..<<<<<<<.<<<<<<<<<<<<<<<<<<<<.....<<<<......>>>>.
((......<<<.....))>>>....>>>>>>>>>..>>>>>>>....>>>
>>>>>>>>........<<<<<<<........>>>>>>>.....<<<<<<.
.>>>>>>..>>>..................................<<..
..>>...............<<<......>>>...................
...............<<<<<.<<<<<<.....<<<<...<<<..<<<<<<
<<<.....>>>>>>>>>......>>>...>>>>..<<<<<<<.<<<<<<<
<<<<<<<<.....<<<<<<<<<......<<<<<......>>>>>......
.>>>>>>>>..>.>>>>>.>>>>>>>>>>........<<<....>>>...
..>>>>>>>....>>>>>>.>>>>>..<<<<........>>>><<<<<<.
...<<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>.......
....<<<<<..<<<<<....>>>>>...>>>>>.<<<<<<<<.......>
>>>.>>>>....>>>>>>.>>>>>>..<<.<..<<<<<<<....>>>>>>
>.....>.>>..<<<<<<....<.<........>.><<<<<<<<<....<
<<.<<<<...>>>>>>>..>>>>>>>.>>..<<<<.<<<.<.....>.>>
>.>>>>....<<<......>>>...<<<<<<<..<<<<(((.....<<<<
<<.....<<.......<<<.<<<<<<<<<<.......<<<<<.<<....<
<.........>>....>>.........<<......>>...>>>>>...>>
>>>>>>>>>>>......))).>>...>>>>>>.>>>>..>>>>>>><<<<
<<<<<.........>>>>>>>>>....>>>>>><.<<<<<<<<.<<....
..<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>>
<<.....<<.>>....>>....<<<<.......>>>>.....<<<<<...
.<..>....>>>>>.<<<<<<<......>>>>>>>..<<<<<<<<..<<<
<.<.<<<<<<...............>>>>>>.><<<<<...<<<<....<
<<<<<<<.<...>.>>>..>>>>>...>>>>.>>>>>.<<<<...<<<<<
...........>>>>>...>>>>.>>>>....>>>>>>>>.<<<<<<...
...<<..........<<<<<<.....>>>>>>......>>.......<<<
<<<...<<<<<.<..<<<......>>>..>.>>>>>.>>>>>>.......
.....>>>>>>.<<<<<<.<..<.......>..>.....<<<<<<<<<.<
<<....<<<..>>>...>>>.>>>.>>>>>>..>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ohw Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		S15 H16 R24 S26 H28 K31 S35 S36 K43 T44 R45 Y47 N48 W49 K52 A53 R55 R56
Binding residue
(residue number reindexed from 1)		S1 H2 R10 S12 H14 K17 S21 S22 K29 T30 R31 Y33 N34 W35 K38 A39 R41 R42
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0030687 preribosome, large subunit precursor
GO:0044391 ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ohw, PDBe:7ohw, PDBj:7ohw
PDBsum7ohw
PubMed34813592
UniProtP49166|RL37A_YEAST Large ribosomal subunit protein eL37A (Gene Name=RPL37A)

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