Structure of PDB 7nhm Chain j Binding Site BS01 |
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| >7nhm Chain a (length=1531)
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ggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaauaca
ugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcggcg
gacgggugaguaacacguggauaaccuaccuauaagacugggauaacuuc
gggaaaccguagcuaauaccggauaauauuuugaaccgcaugguucaaaa
gugaaagacggucuugcugucacuuauagauggauccgcgcugcauuagc
uaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccuga
gagggugaucggccacacuggaacugagacacgguccagacuccuacggg
aggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagcaac
gccgcgugagugaugaaggucuucggaucguaaaacucuguuauuaggga
agaacauauguguaaguaacugugcacaucuugacgguaccuaaucagaa
agccacggcuaacuacgugccagcagccgcgguaauacguagguggcaag
cguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaagu
cugaugugaaagcccacggcucaaccguggagggucauuggaaacuggaa
aacuugagugcagaagaggaaaguggaauuccauguguagcggugaaaug
cgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucugua
acugacgcugaugugcgaaagcguggggaucaaacaggauuagauacccu
gguaguccacgccguaaacgaugagugcuaaguguuagggggccccuuag
ugcugcagcuaacgcauuaagcacuccgccuggggaguacgaccgcaagg
uugaaacucaaaggaauugacggggacccgcacaagcgguggagcaugug
guuuaauucgaagcaacgcgaagaaccuuaccaaaucuugacauccuuug
acaacucuagagauagagccuuccggacaaagugacagguggugcauggu
ugucgucagcucgugucgugagauguuggguuaagucccgcaacgagcgc
aacccuuaagcuuaguugccaucauuaaguugggcacucuaaguugacug
ccggugacaaaccggaggaagguggggaugacgucaaaucaucaugcccc
uuaugauuugggcuacacacgugcuacaauggacaauacaaagggcagcg
aaaccgcgaggucaagcaaaucccauaaaguuguucucaguucggauugu
agucugcaacucgacuacaugaagcuggaaucgcuaguaaucguagauca
gcaugcuacggugaauacguucccgggucuuguacacaccgcccgucaca
ccacgagaguuuguaacacccgaagccgguggaguaaccuuuuaggagcu
agccgucgaaggugggacaaaugauuggggugaagucguaacaagguagc
cguaucggaaggugcggcuggaucaccuccu |
...<<<<....((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.
<<<..<<<..<<.<<<........................>>>.>>>>>.
.....<<........<<<<<<<..<<...<<<<<<<.<<<<.....<<.<
<<....>>>.>>......>>>>......<<<<<<<<<....>>>>>>>>>
......<<<<<<...>>>>>>.>>>>>>>..>>>>>>>>>.<<<....<<
<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<..
..>>>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>
>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>
>>>>>..<<<<......<<<<....>>>>.....>>>>...<<<<<<<..
.....<.<<<<<<..........>>>>>>.>........>>>>>>...>.
.<<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>..>
>>>>>>>>..........<<<((.....<<<<<..<<<.<<<<<<<.<<<
<<<<<<.......<<<<<<.....>>>>>>.....>>>>>>>..>>>>>>
>>>...<<<<<<<<...<<<<<<<....<<<<<<<<...<<<......>>
>......>>>>>>>>...........<<....>>.>>>>>>>..>>>>>.
>>>...>>>..>>>>>....<<<<<<<...<...<<<<.<.....>.>>>
>...>>>>>>>>..........<<<<<<..<<<<<<<<<<<..>>>>>>>
>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>
>>....>>>..))))..<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<
<<......<<........>>..........<<<<<<<......<<<<<<.
....<<<<<....>>>>>..........>>>>.>>.<<<.<<<..<<<<<
<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>>>..
...<<<<.<<<<<<<..<<..<<<......>>>>>...>>>>>>>.....
<<<<<.....>>>>>........>>>>.........>>>...>>>>>>>>
>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<.
..<<<....>>>...>>....>>>.....>>>>>>>......<....<<<
<<<<........>>>>>>>....>.....>>>>>>....<<<<<<<....
.....>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<
<<.<<<..<<<<<<..<<<<....<.<<<<..<<<..<<<...>>>.>>>
.>>>>.>...>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<<<
<<<<<<....>>>>>>>>>............ |
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| PDB | 7nhm Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens. |
| Resolution | 3.1 Å |
Binding residue
(original residue number in PDB) | T11 R13 R14 K15 N16 V18 R20 R22 N68 H70 G71 G72 G73 F74 T75 G76 Q77 R87 R97 K101 T107 R108 R111 K113 E114 R115 K116 K117 P118 G119 K121 R124 R125 S126 Q128 F129 S130 R132 |
Binding residue
(residue number reindexed from 1) | T6 R8 R9 K10 N11 V13 R15 R17 N63 H65 G66 G67 G68 F69 T70 G71 Q72 R82 R92 K96 T102 R103 R106 K108 E109 R110 K111 K112 P113 G114 K116 R119 R120 S121 Q123 F124 S125 R127 |
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| Enzyme Commision number |
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