Structure of PDB 7l08 Chain j Binding Site BS01

Receptor Information
>7l08 Chain j (length=93) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGQWRLQQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAERETF
ARRVVLLSQEMDAGLQAWQLRQQKLQEEQRKQENALKPKGASL
Ligand information
>7l08 Chain A (length=1527) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccuc
uaaauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuug
gacacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauag
uaggccuaaaagcagccaccaauuaagaaagcguucaagcucaacaccca
cuaccuaaaaaaucccaaacauauaacugaacuccucacacccaauugga
ccaaucuaucacccuauagaagaacuaauguuaguauaaguaacaugaaa
acauucuccuccgcauaagccugcgucagauuaaaacacugaacugacaa
uuaacagcccaauaucuacaaucaaccaacaagucauuauuacccucacu
gucaacccaacacaggcaugcucauaaggaaagguuaaaaaaaguaaaag
gaacucggcaaaucuuaccccgccuguuuaccaaaaacaucaccucuagc
aucaccaguauuagaggcaccgccugcccagugacacauguuuaacggcc
gcgguacccuaaccgugcaaagguagcauaaucacuuguuccuuaaauag
ggaccuguaugaauggcuccacgaggguucagcugucucuuacuuuuaac
cagugaaauugaccugcccgugaagaggcgggcauaacacagcaagacga
gaagacccuauggagcuuuaauuuauuaaugcaaacaguauaccaaaccu
gcauuaaaaauuucgguuggggcgaccucggagcagaacccaaccuccga
gcaguacaugcuaagacuucaccagucaaagcgaaccucaauugauccaa
uaacuugaccaacggaacaaguuacccuagggauaacagcgcaauccuau
ucuagaguccauaucaacaauaggguuuacgaccucgauguuggaucagg
acaucccgauggugcagccgcuauuaaagguucguuuguucaacgauuaa
aguccuacgugaucugaguucagaccggaguaauccaggucgguuucuau
cuacuuucaaauuccucccuguacgaaaggacaagagaaauaaggccuac
uucacaaagcgccuucccccguaaaugauaucaucucaacuuaguauuau
acccacacccacccaagaacaggguuu
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<..<<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>...>..>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
....>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>
>>>.<.<<<......>>>.>..<<<.<<<...<..............<..
...<<.........>>.....>.......<<<......>>>.........
...........................>...>>>>>>........>>>>>
>...<<<<<......>>>>>.........>>>>>><......<<..<<<.
...>>><<<<..<<<<........<<<<<..............>>>>>..
....<<<...<<<<.......................>>>>.......>>
>.....<<......>>.>>>>.....>>>>..<<<<...<<<<<<<<.<<
................<<<<<<..<<<.........>>>...<<<<<<..
...........>>>>>>....<<<.<<<..<<<<<....>>>..>>>>><
<<<<<......>>>>>>........<...........<<<<<<.....>>
>>>>.....>....>>>....>>.>>>>........>>.>>>>>>>>>>>
>.>>.....>.....<<<<<........>>>>>.......<<..<<<.<<
......<<<<.<<<<<<..<<<<<.<<<<<<<<................>
>>>>>>>>>>>>..<<<<.....>>>><<<<<<...........>>>>>>
..<<.....<<<..<<<<.....>>>>..>>>....>>.........<<<
....>>>............>>>>..>>>>>>.......<<<..<.<<<<<
<...<<.......>>...>>>>>>...>.>>.>.......<.<<<.<<<<
<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>>>>....
.>>>>>..>...>>>..>....<<<<<<<....>>>.>>>>....>>..>
>>.>>...<.<<<.<<<.................>>>.>>><<<<<...<
<<....>>>.>>>>>......<<<................>>>......>
..........<<<<.......>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7l08 Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance.
Resolution3.49 Å
Binding residue
(original residue number in PDB)		G24 G25 N36 P37 S38 M60 K61 G62 R66
Binding residue
(residue number reindexed from 1)		G1 G2 N13 P14 S15 M37 K38 G39 R43
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005762 mitochondrial large ribosomal subunit

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7l08, PDBe:7l08, PDBj:7l08
PDBsum7l08
PubMed34127662
UniProtA8K7J6

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