Structure of PDB 6spe Chain j Binding Site BS01

Receptor Information
>6spe Chain j (length=96) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHV
NKDARDQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLG
Ligand information
>6spe Chain a (length=1526) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aacugaagaguuugaucauggcucagauugaacgcuggcggcaggccuaa
cacaugcaagucgagcggauaaagggagcuugcuccuggauucagcggcg
gacgggugaguaaugccuaggaaucugccugguagugggggauaacgucc
ggaaacgggcgcuaauaccgcauacguccugagggagaaagugggggauc
uucggaccucacgcuaucagaugagccuaggucggauuagcuaguuggug
ggguaaaggccuaccaaggcgacgauccguaacuggucugagaggaugau
cagucacacuggaacugagacacgguccagacuccuacgggaggcagcag
uggggaauauuggacaaugggcgaaagccugauccagccaugccgcgugu
gugaagaaggucuucggauuguaaagcacuuuaaguugggaggaagggca
guaaguuaauaccuugcuguuuugacguuaccaacagaauaagcaccggc
uaacuucgugccagcagccgcgguaauacgaagggugcaagcguuaaucg
gaauuacugggcguaaagcgcgcguaggugguucagcaaguuggauguga
aauccccgggcucaaccugggaacugcauccaaaacuacugagcuagagu
acgguagagggugguggaauuuccuguguagcggugaaaugcguagauau
aggaaggaacaccaguggcgaaggcgaccaccuggacugauacugacacu
gaggugcgaaagcguggggagcaaacaggauuagauacccugguagucca
cgccguaaacgaugucgacuagccguugggauccuugagaucuuaguggc
gcagcuaacgcgauaagucgaccgccuggggaguacggccgcaagguuaa
aacucaaaugaauugacgggggcccgcacaagcgguggagcaugugguuu
aauucgaagcaacgcgaagaaccuuaccuggccuugacaugcugagaacu
uuccagagauggauuggugccuucgggaacucagacacaggugcugcaug
gcugucgucagcucgugucgugagauguuggguuaagucccguaacgagc
gcaacccuuguccuuaguuaccagcaccucgggugggcacucuaaggaga
cugccggugacaaaccggaggaagguggggaugacgucaagucaucaugg
cccuuacggccagggcuacacacgugcuacaauggucgguacaaaggguu
gccaagccgcgagguggagcuaaucccauaaaaccgaucguaguccggau
cgcagucugcaacucgacugcgugaagucggaaucgcuaguaaucgugaa
ucagaaugucacggugaauacguucccgggccuuguacacaccgcccguc
acaccaugggaguggguugcuccagaaguagcuagucuaaccgcaagggg
gacgguuaccacggagugauucaugacuggggugaagucguaacaaggua
gccguaggggaaccugcggcuggauc
.......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....
<<<.<<<..<<<..<<.<<....<.<<<<..>>>>.>....>>.>>>>>.
.....<<.......<<<<<<<..<<...<<<<<<<<<.<<.....<<<<<
<....>>>>>>......>>.>.....<<<....>>>....<<<<<<..<<
....>>>>>>>>>>>>>>>>..>>.>>>>>>><<<....<<<..<<<<<<
<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...
>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>
>>.........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<
<<......<<<<<..>>>>>.....>>>>...<.<<<<<......<<<<<
<<<<<.......>>>>>>>>>>........>>>>>....>..<<<<<(((
...<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>>.
.........<<<((.....<<<<...<<<.<<<<<<..<<<<<<<<<<..
....<<<<<<.....>>>>>>....>>>>>>>>..>>.>>>>>>...<<<
<<<<<...<<<<<<<....<<<<<<<<<..<<<......>>>.....>>>
>>>>>>...........<<....>>.>>>>>>>..>>>>.>>>>...>>>
...>>>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>
>>>..........<<<<<<..<<<<<<<<<<<<.....>>>>>>>>>>>>
...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>..
..>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<..
....<<........>>..........<<<<<<<......<<<<<<<....
..<<<....>>>.......<<....>>..>>>>>.>>.<<<.<<<..<<<
<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>>>
.....<<<<.<<<<<<<...<<..<<<.....>>>>>....>>>>>>>..
...<<<<<.....>>>>>........>>>>.........>>>...>>>>>
>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..
<<...<<<....>>>...>>....>>>.....>>>>>>>......<....
<<<<<<<........>>>>>>>....>.....>>>>>>....<<<<<<<.
........>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<
.<<<<.<<<..<<<<<<<<<<<<....<<<<<<.<<<<..<<....>>.>
>>>>>>>>>...>>>>>>>>>>>>..>>>.>>>>..>.>>...>.....<
<<<<<<<<....>>>>>>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6spe Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		D19 G38 P39 I40 P41 L42 P43 T50 I53 P55 V57 N58 K59 R62 H70
Binding residue
(residue number reindexed from 1)		D12 G31 P32 I33 P34 L35 P36 T43 I46 P48 V50 N51 K52 R55 H63
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6spe, PDBe:6spe, PDBj:6spe
PDBsum6spe
PubMed31611393
UniProtE2RXT0

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