Structure of PDB 6j6h Chain j Binding Site BS01

Receptor Information
>6j6h Chain j (length=75) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSTPELKKYMDKKILLNINGSRKVAGILRGYDIFLNVVLDDAMEINGEDP
ANNHQLGLQTVIRGNSIISLEALDA
Ligand information
>6j6h Chain D (length=179) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagcagcuuuacagaucaauggcggagggaggucaacaucaagaacugug
ggccuuugccuauagaacuuauaacgaacaugguucuugccuuuuaccag
aaccauccggguguugucuccauagaaacagguaaagcuguccguuacug
ugggcuugccauauuuuuuggaacuuuuc
...<<<<<<.<<<<.......<<<<..<<<<<.<<<<<<<.....<<<<<
<<<....>>>>>>>>..............<<<<<<<<...........>>
>>>>>>...>>>>>>>>>>>>......<<<<......>>>>>>>>..>>>
>>>>>.>>.....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6j6h Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Resolution3.6 Å
Binding residue
(original residue number in PDB)
F35 N37 R64 G65 N66
Binding residue
(residue number reindexed from 1)
F34 N36 R63 G64 N65
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000387 spliceosomal snRNP assembly
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008150 biological_process
GO:0008380 RNA splicing
GO:0036261 7-methylguanosine cap hypermethylation
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005682 U5 snRNP
GO:0005685 U1 snRNP
GO:0005686 U2 snRNP
GO:0005687 U4 snRNP
GO:0005737 cytoplasm
GO:0032991 protein-containing complex
GO:0034719 SMN-Sm protein complex
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP
GO:0071004 U2-type prespliceosome
GO:0071011 precatalytic spliceosome
GO:0071013 catalytic step 2 spliceosome
GO:0097526 spliceosomal tri-snRNP complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6j6h, PDBe:6j6h, PDBj:6j6h
PDBsum6j6h
PubMed30879786
UniProtP40204|RUXG_YEAST Small nuclear ribonucleoprotein G (Gene Name=SMX2)

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