Structure of PDB 6gsm Chain j Binding Site BS01

Receptor Information
>6gsm Chain j (length=249) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELS
RRRIRSIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKY
QKSKTVHSILRYCAEKFQIPLEELYKTIAWPLSRKFGHAYEAFKLSIIDE
TVWEGIEPPSKDVLDELKNYISVKIRADVEVSCFSYEGIDAIKDALKSAE
DVKVKLVAAPLYVLTTQALDKQKGIEQLESAIEKITEVITKYGGVCNIT
Ligand information
>6gsm Chain 1 (length=74) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcgccguggcgcaguggaagcgcgcagggcucauaacccugauguccuc
ggaucgaaaccgagcggcgcuacc
<<<<<<<..<<<<.......>>>>.<<<<<.......>>>>>.......<
<<.......>>>..>>>>>>>...
Receptor-Ligand Complex Structure
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PDB6gsm Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Resolution5.15 Å
Binding residue
(original residue number in PDB)		R57 S58 K61 L62 R64 G66 E100 Q103 T107 S110 N171 V223
Binding residue
(residue number reindexed from 1)		R55 S56 K59 L60 R62 G64 E98 Q101 T105 S108 N169 V207
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity

View graph for
Molecular Function
External links
PDB RCSB:6gsm, PDBe:6gsm, PDBj:6gsm
PDBsum6gsm
PubMed34648019
UniProtP20459|IF2A_YEAST Eukaryotic translation initiation factor 2 subunit alpha (Gene Name=SUI2)

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