Structure of PDB 5t5h Chain j Binding Site BS01

Receptor Information
>5t5h Chain j (length=104) Species: 5693 (Trypanosoma cruzi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRVQYRRRMHYATRGNRMKLVRTPGNRLVMQKRVKRSQGPHTPWVLGHKR
LAGTKALRHTEARLASRHEKSTSRPYGGVLSHEQVRDRIVRAFLIEEQRI
VKRA
Ligand information
>5t5h Chain A (length=1278) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cagaccugaguguggcaggacuacccgccgaacuuaagcauauuacuaag
cggaggaaaagaaaacaaccgugauucucucagucagcggcgagcgaaga
gggauccaacucguugccgaaucgguucuuauaggaacuugaguuguggc
aauggugcaggaauggugaaauucaaagcaaacccguugcuacaucaugu
gaguauugagccaaagaagguguuagcccauugagccaugaaccuaagag
aguagcacugcuugggagugcagugucaagcuggcagguaugugucugcc
aaaguuaaauacagaguaggaagaccgauagcgaacaaguagcgugagcg
aaaguuugaaaagcacuuuggaaagagagugacauagaccugaagucgug
acaauaauggaaguaccuccauuucgccaaaaccagccucuacugagcaa
gaacgaggucaugguuuuggcggaaauggggugcccccacccgucuugaa
acacggaccaaggagucaaacagacgcgcaagggagaagauaucaguacu
ucucucguacugaaagggagauuguggugugcacacuugcccaacaccga
ccggccccggguugaguuggagugugccuguuuggacccgaaagguggug
aacuaugccugaacaaggugaagcccggggaaacucggguggaggccugu
agcgaugcugacgugcaaaucgcucgcaugauuuggguaucggagcgaaa
gacucaucgaaccaccuaguagcugguucacaucgaaguuucccucagga
uagcuggugcuugaaaaaguauugugcgguaaagcuuuaaaugugcaacu
ugccaaagcaagguauuaaggcaccaagugggccuucuucgguaagcgga
gcaggcgaugcggaaugaaccgcuuagggauauguggcgucaaaacuuau
gggcucacgaacaauggaugacgcucaagcccaauuagugcccauuauuc
cuuugguaagggcgagaaaguguagcccuuccgauguagauguggcgugg
agguaaggacgaagcugauggcgugagccucagauggaccagccucuagu
gcagaucuugguuggcguagcaaagaucuaacggaacguuggauacugga
gcggggaaggauuucgugccaacggcacucguacacgaguuguucggaua
cugagcacaacguuacaccguuuuuaggaaaaggggcaacagagaaccug
ggauuauauuccaaaaagaaauugcaug
.......................<<<<<......<......>.......>
>>>.>.........<<....>>...<<<<<......<<.....>>....>
>>>>....<<<..<<<<<<..<<<<<<<......>>>>>.>>....>>>>
>>......<<<.<<<<<......<<<<<<<.......>>>>.<.....>.
.....>>>.<<.......((.....>>)).....>>>>>...>>>.....
....<<<<<<<........>>>>>>>......<<<<<........>>>>>
..>>>....................................<<....>>.
...............<<<......>>>.......................
.......<<<..<<<<<<.<<<<<.<<<<<<<<<<<<<<...<<.>>...
.....>>>>..>>>>>>>>>>..>>>>>>>>>>>..>>>.<<<<......
..>>>><<<<<<...<<<<<<<<.<<<<<..<<<<..<<.<<<..>>>>>
..>>>>...<<....>>........<<<<<...<<..>>....>>>>><<
<<<<<<<.>>>>>>.>>>...>>>>>.>>>>>>>>.<<.<...<<<<<<.
....<<<<<<<<<..<<<....<<<<<<......>>>>>>.....>>>..
.<<<<.<<.<<........>>>>>>>>....>>>>>>>>>...<<.....
..>>......>>>>>>......>.>>...<<<<<....<.<<<....>>>
(><<<<<<<<<.....<<...<<<<<<<...<<<.>>>...>>>>>>><<
<<<....>>>>>...>>..>>>>>>>.>>).<<<<.<<<<<.....>>>>
>.>>>>...<<<<......>>>>..<<<<<<<...<<<(((......<..
<<<<....<..........))).>....>>>>.>.....>>>...>>>>>
>><<<<.<<<<<.............>>>>>>>>>....>>>>>.....<<
<<<<..........<<<..<<<....>>>.>>>........>>>>>>...
......>>>>>>..............<<<<<<<...>>>>>>>.......
.............<<<<<....<<.....>>..>>>>>....<<......
....<<.<<<<<......>>>>...........>.>>..........<<<
<.........>>....>>.>>.......
Receptor-Ligand Complex Structure
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PDB5t5h Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.
Resolution2.54 Å
Binding residue
(original residue number in PDB)		R5 Q7 R9 R10 R11 M12 H13 Y14 T16 R17 T26 G28 R30 Q34 K38 R61 H62 T63 R66 L67
Binding residue
(residue number reindexed from 1)		R2 Q4 R6 R7 R8 M9 H10 Y11 T13 R14 T23 G25 R27 Q31 K35 R58 H59 T60 R63 L64
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5t5h, PDBe:5t5h, PDBj:5t5h
PDBsum5t5h
PubMed27791004
UniProtQ4DB26

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