Structure of PDB 8wib Chain i Binding Site BS01

Receptor Information
>8wib Chain i (length=131) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TMTDPIADFLTRLRNANSAYHDEVTLPHSKLKANIAEILKREGYISDYRT
EDARVGKSLVVQLKYGPSRERSIAGLRRVSKPGLRVYAKSTNLPRVLGGL
GVAIISTSSGLLTDRQAARQGVGGEVLAYVW
Ligand information
>8wib Chain a (length=1515) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuggagaguuugauccuggcucaggacgaacgcuggcggcgugcuuaaca
caugcaagucgaacggaaaggcccuuucggggguacucgaguggcgaacg
ggugaguaacacgugggugaucugcccugcacuuugggauaagccuggga
aacugggucuaauaccgaauacacccugcuggucgcauggccugguaggg
gaaagcuuuugcggugugggaugggcccgcggccuaucagcuuguuggug
gggugauggccuaccaaggcgacgacggguagccggccugagagggugac
cggccacacugggacugagauacggcccagacuccuacgggaggcagcag
uggggaauauugcacaaugggcgcaagccugaugcagcgacgccgcguga
gggaugacggccuucggguuguaaaccucuuucagcacagacgaagcgca
agugacgguaugugcagaagaaggaccggccaacuacgugccagcagccg
cgguaauacguaggguccgagcguuguccggaauuacugggcguaaagag
cucguaggugguuugucgcguuguucgugaaaacucacagcuuaacugug
ggcgugcgggcgauacgggcagacuagaguacugcaggggagacuggaau
uccugguguagcgguggaaugcgcagauaucaggaggaacaccgguggcg
aaggcgggucucugggcaguaacugacgcugaggagcgaaagcgugggga
gcgaacaggauuagauacccugguaguccacgccguaaacgguggguacu
agguguggguuuccuuccuugggauccgugccguagcuaacgcauuaagu
accccgccuggggaguacggccgcaaggcuaaaacucaaaggaauugacg
ggggcccgcacaagcggcggagcauguggauuaauucgaugcaacgcgaa
gaaccuuaccuggguuugacaugcacaggacgccggcagagaugucgguu
cccuuguggccugugugcagguggugcauggcugucgucagcucgugucg
ugagauguuggguuaagucccgcaacgagcgcaacccuugucucauguug
ccagcacguuaugguggggacucgugagagacugccggggucaacucgga
ggaagguggggaugacgucaagucaucaugccccuuauguccagggcuuc
acacaugcuacaauggccgguacaaagggcugcgaugccgugagguggag
cgaauccuuucaaagccggucucaguucggaucggggucugcaacucgac
cccgugaagucggagucgcuaguaaucgcagaucagcaacgcugcgguga
auacguucccgggccuuguacacaccgcccgucacgucaugaaagucggu
aacacccgaagccgguggccuaacccuuguggagggagccgucgaaggug
ggaucggcgauugggacgaagucguaacaagguagccguaccggaaggug
cggcuggaucaccuc
.....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<
<.<<<..<<<..<<.<..<<<<<<<....>>>>>.>>>..>>>>>.....
.<<........<<<<<<<..<<...<<<<<<<<<<<<.....<<<<<<..
..>>>>>>......>>>>.....<<<<<<<<<<<<..>>>>>.>>>>>>>
....<<....>>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<
<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...
>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>
>>.........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<
<<......<<<<....>>>>.....>>>>...<.<<<<<......<<...
.>>.......>>>>>....>..<<<<<(((...<<<<<.....<<.)))>
>.......>>>>>>>>>>..>>>>>>>>>..........<<<((.....<
<<<...<<<.<<<<<<<.<<<<<<<<<<.....<<<<<<<.....>>>>>
>>...>>>>>>>..>>>>>>>>>>...<<<<<<<<...<<<<<<<....<
<<<<<<<<..<<<......>>>.....>>>>>>>>>...........<<.
...>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...
<<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<.
.<<<<<<<<<<<<.......>>>>>>>>>>>>...<<..))>>.....>>
>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<
.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>..
........<<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>.
<<.....>>.>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<.
...>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<....
<<..<<<......>>>>>.....>>>>>>.....<<<<<.....>>>>>.
.......>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>
.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>
>....>>>......>>>>>>>......<....<<<<<<<........>>>
>>>>....>.....>>>>>>....<<<<<<<..........>>>>>>>..
....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<
..<<<<....<.<<<<..<<<..<<.....>>.>>>.>>>>.>...>>>>
..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>
>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8wib Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		T2 T4 T12 R13 R15 N16 H22 S30 K31 R55 V56 K82 P83 R86 Y88 K90 S91 S107 T108 S109 G122
Binding residue
(residue number reindexed from 1)		T1 T3 T11 R12 R14 N15 H21 S29 K30 R54 V55 K81 P82 R85 Y87 K89 S90 S106 T107 S108 G121
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8wib, PDBe:8wib, PDBj:8wib
PDBsum8wib
PubMed38245551
UniProtA0QSG3|RS8_MYCS2 Small ribosomal subunit protein uS8 (Gene Name=rpsH)

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