Structure of PDB 8s8j Chain i Binding Site BS01

Receptor Information
>8s8j Chain i (length=95) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRELIYKEEGQEYAQITKMLGNGRVEASCFDGNKRMAHIRGKLRKKVWMG
QGDIILVSLRDFQDDQCDVVHKYNLDEARTLKNQGELPENAKINE
Ligand information
>8s8j Chain 2 (length=1798) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacauggauaucug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacuccuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaacuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaguagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggucugguug
uccgguccgacuuuaugucgcgcacugguuuucaaccggaucuuuccuuc
uggcuaaccuguacuccuugugggugcaggcgaaccaggacuuuuacuuu
gaaaaaauuagaguguucaaagcaggcgaaagcucgaauauauuagcaug
gaauaauggaauaggacguuugguucuauuuuguugguuucuaggaccau
cguaaugauuaauagggacggucgggggcaucaguauucaauugucagag
gugaaauucuuggauuuauugaagacuaacuacugcgaaagcauuugcca
aggacguuuucauuaaucaagaacgaaaguuaggggaucgaagaugauca
gauaccgucguagucuuaaccauaaacuaugccgacuagggaucgggugg
uguuuuucuuaugacccacucggcaccuuacgagaaaucaaagucuuugg
guucuggggggaguauggucgcaaggcugaaacuuaaaggaauugacgga
agggcaccaccaggaguggagccugcggcuuaauuugacucaacacgggg
aaacucaccagguccagacacaauaaggauugacagauugagagcucuuu
cuugauuuugugggugguggugcauggccguucuuaguugguggagugau
uugucugcuuaauugcgauaacgaacgagaccuuaaccuacuaaauaggg
uugcuggcacuugccgguugacucuucuuagagggacuaucgguuucaag
ccgauggaaguuugaggcaauaacaggucugugaugcccuuagacguucu
gggccgcacgcgcgcuacacugacggagccagcgaguacaaccuuggccg
agaggucuggguaaucuugugaaacuccgucgugcuggggauagagcauu
guaauuauugcucuucaacgaggaauuccuaguaagcgcaagucaucagc
uugcguugauuacgucccugcccuuuguacacaccgcccgucgcuaguac
cgauugaauggcuuagugaggccucaggauuugcuuagagaagggggcaa
cuccaucucagagcgaagaaucuggucaaacuuggucauuuagaggaacu
aaaagucguaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<..{.[[[[.>>>><<<<.<<<<<<...<............<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<................<<.....<<.
<<.......>>.>>......>>........<<<<<..<<....>>..>>>
>><...<<<<<<......(((((((.<<<....>>>....<<......>>
>>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>
>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>...
...>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<........
..>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<.
....>>>..>>>.........>.....<<<<<<<<<.<.......>..>>
>>>>.>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>
>>>.........<<<[[.....<.<<...<<<.<<....<.<<<<<<<<<
..<<<..<<<.......>>>....>>>.....>>>>>>>>>.>.....<<
<<<....<.<...<<.......>>...>.>....>>>.>>...<<<<<.<
<.......<<...<.......>..<<<....>>>....>>......>>.>
>..>>>.........<<<..<<<<<<<<.....))))))).>>>>>>>>.
>>>.....>>....<<<<<<.<<...<<<<..<<<.<<<<<<.<...<<<
......>>>......>.>>>>>>.>>>.......<<....>>...>>>>.
.>>.>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<....
.....>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<<
.<<<........>>>>>>>>>>>..>>>...<<..]]>>...>>.....>
>>.>>>.<<<......<<<......>>>....>>>..]]]].}<<<<<.<
<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<........>>...
.......<<<<<.<....<<<<<........<<.<<<........>>>.>
>......>>>>>...<<.<<<..<<.<<<<<<....<<<.<<<<<....>
>>...<<<......>>>...>>.>>>....<<<<<.<<..<<<<..<<<<
<<<<<<<<....>>>>>>.>>>>>>..>>>>.>>....<<<<<<.....>
>>>>>.......>>>>>....>>>.>>>.....>>>>>>>.....>.>>>
>>...>>.>>>>.>>>.....<<<<<<<......<<.....<<<.<<<<.
...>>>>.>>>....>>.......>>>>>>>......<....<<<<<<..
........>>>>>>....>.....>>>>>>....<<<<<<<<.......>
>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<
<....<<<<<<<<.<<<..<<<<..<...<<<<<<..<............
.......>...>>>>>>...>..>>>>..>>>.>>>>>>>>...>>.>>>
>...>.>>...>.....<<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8s8j Structural basis of AUC codon discrimination during translation initiation in yeast.
Resolution4.7 Å
Binding residue
(original residue number in PDB)
K23 K40 M41 L42 G43 N44 R46 R62 G63 K64 R66 W70 M71
Binding residue
(residue number reindexed from 1)
K1 K18 M19 L20 G21 N22 R24 R40 G41 K42 R44 W48 M49
External links
PDB RCSB:8s8j, PDBe:8s8j, PDBj:8s8j
PDBsum8s8j
PubMed39193907
UniProtP38912|IF1A_YEAST Eukaryotic translation initiation factor 1A (Gene Name=TIF11)

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