Structure of PDB 8rc0 Chain i Binding Site BS01
Receptor Information
>8rc0 Chain i (length=81) Species:
9606
(Homo sapiens) [
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KLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSMNTHLKAVKMTLKNRE
PVQLETLSIRGNNIRYFILPDSLPLDTLLVD
Ligand information
>8rc0 Chain 5 (length=104) [
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acucugguuucucuucagaucgcauaaaucuuucgcacuaaagauuuccg
uggagaggaacaacucugaguccaauuuuuugaggccuugcuuuggcaag
gcua
<<<<.<<<<<<<<<<<<........<<<<<<<<......>>>>>>>>...
>>>>>>>>>>>....>.>>>>............<<<<<<<<....>>>>>
>>>.
Receptor-Ligand Complex Structure
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PDB
8rc0
Structure of the human 20S U5 snRNP.
Resolution
3.2 Å
Binding residue
(original residue number in PDB)
S35 G62 N63
Binding residue
(residue number reindexed from 1)
S34 G61 N62
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0005515
protein binding
Biological Process
GO:0000245
spliceosomal complex assembly
GO:0000387
spliceosomal snRNP assembly
GO:0000398
mRNA splicing, via spliceosome
GO:0006396
RNA processing
GO:0006397
mRNA processing
GO:0008380
RNA splicing
GO:0036261
7-methylguanosine cap hypermethylation
GO:1903241
U2-type prespliceosome assembly
Cellular Component
GO:0000243
commitment complex
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005681
spliceosomal complex
GO:0005682
U5 snRNP
GO:0005684
U2-type spliceosomal complex
GO:0005685
U1 snRNP
GO:0005686
U2 snRNP
GO:0005687
U4 snRNP
GO:0005689
U12-type spliceosomal complex
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0030532
small nuclear ribonucleoprotein complex
GO:0034709
methylosome
GO:0034715
pICln-Sm protein complex
GO:0034719
SMN-Sm protein complex
GO:0046540
U4/U6 x U5 tri-snRNP complex
GO:0071005
U2-type precatalytic spliceosome
GO:0071007
U2-type catalytic step 2 spliceosome
GO:0071011
precatalytic spliceosome
GO:0071013
catalytic step 2 spliceosome
GO:0097526
spliceosomal tri-snRNP complex
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Cellular Component
External links
PDB
RCSB:8rc0
,
PDBe:8rc0
,
PDBj:8rc0
PDBsum
8rc0
PubMed
38467877
UniProt
P62314
|SMD1_HUMAN Small nuclear ribonucleoprotein Sm D1 (Gene Name=SNRPD1)
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