Structure of PDB 8eup Chain i Binding Site BS01

Receptor Information
>8eup Chain i (length=98) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APGLVVGLNKGKTLTKRQLPERPSRRKGHLSKRTAFVRSIVREVAGFAPY
ERRVMELIRNSQDKRARKLAKKRLGTLKRAKGKIEELTSVIQSSRLAH
Ligand information
>8eup Chain 1 (length=1422) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucaaaucagguaggacuacgcgcugaacaauaagcgcaggaaaa
gaaaauaaccaugauucccucaguaacggugaagcgggaaaagcucaaau
uugaaaucuggcaacauuucuuuuguuguccgaguuguaauuucaagaag
cugcuuugaguguagacgaucggucuaaguuccuuggaacaggacgucag
agagggugagaaccccgucuuuggucgauuggauaugccauauaaagcgc
uuucgaagagucgaguuguuugcagcucuaaauggguggucaucuaaagc
uaaauauuggcgagagaccgauagcgaacaaguagagugaucgaaagaug
aaaagaacuuugaaaagagaguuaaauaguacgugaaauugcugaaaggg
aagcauuggaaaucagucuuaccugggugagaucaguagucucucgagac
uaugcacucugaaccugugguaggucagcaucaguuuucgggggcggaaa
aagaauaagggaagguggcuguuuauagcccuuguuguaauacguccacu
ggggacugaggacugcggcuugccaaggaugcugacauaaugguuuucaa
uggcccgucuugaaacacggaccaaggagucuagcaucuaugcgaguguu
ugggugaugaaaacccauccgcgaaggugggaacgcccuuguggcgugca
ccaucgaagagcauagcuguugggacccgaaagauggugaaccaucuagu
agcugguuccugccgaaguuuccggauagcagaaacucagaucaguuuua
uguguaaaaugagaguuucuagugggccauuuuugguaagcagaacuggc
gaugcgggaugaaccgaacgugagguuaaggugccggaauguacgcucau
cagaaagguguuaguucauaugaacuagcccugggcgcuuaagcguacua
cccauaccucaccgucuggguuagcuuugagaagcucagacgaguaggca
ggcguggagguuugugacgaagccuugggcgugagccugggucgaacagc
cucuagugcagaucuugguggaaguagcuagaucuagcgaaaccacagcc
uggggaacgggccaggcaaucgucgcaaugguaauucaacuuaguacgag
aggaaccguugauucagaucauugguauuugcggccgcggagcuaucauc
ugccggauaacggcugaacgccucuaagccagaauccgugccagaaagcg
acgauuauguauaaaaauagagguaggcuacucuccuguaucguagaaga
ugggcgaugguugaugaaacggaaguguuuuauugacuuguccaugaaau
uccaugaauccauugcauacgacuuuaauguggaacgggguauugagauu
aagccuuuguucccaagauuug
.........................<<<<<........>>>>>.......
....<<....>>..<<<<<......<<.>>.....>>>>>..<<<...<.
......<<.<<<<<<<.......>>>>>>>.>>.......>.....<<<<
<.<<<<<..<<<<<..<<<<<<<<<.....<<<<......>>>>.((...
...<<<.....))>>>......>>>>>>>>>..>>>>>.....>>>>>>>
>.>>........<<<<<<<..>>>>>>>.....<<<<<..>>>>>..>>>
..................................<<....>>........
.......<<<<....>>>>...............................
...<<<<<<<<<<<<.....<<<.<<<<.<<<.<<.<<<<<<<..>>>>>
>>>>...>>>..>>>>..>>>..<<<<<<<.<<<<<<<<<<<<<<<....
......<<<<<.................>>>>>.........>>>>>.>>
>>>>>>>>........<<<..>>>.....>>>>>>>....>>>>>>>>>>
>>..<<<<........>>>><<<<<<....<<<<<<.<<<<<<..<<<..
.<<<<.......>>>>...>>>...<<<<<..<<<<<.....>>>>>...
>>>>>.....>>>>>>.>>>>>>..<<.<..<<<<<<<..>>>>>>>...
..>.>>..<<<<<<......<<..>>..<<<<<<<<<....<<<.<<<<<
<..>>>>>>>>>.>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>
....<<<......>>>...<<<<<<<...<<<(((.....<<<<<<....
.<<..<<<.<<<<<<<<<..>>>>>>>>>>>>.))).>>...>>>>>>.>
>>...>>>>>>><<<<<<<<<............>>>>>>>>>....>>>>
>>..<<<<<<<..<<......<<<<.<<<<....>>>>>>>>...>>.>>
>>>>>........>>>>>><<.....<<<<<..>>>>>....>>....<<
<<<........>>>>>...<<<<<<<..<<<<...<<<<<..........
.......>>>>>..<<<<<...<<<<....<<<..>>>...>>>>..>>>
>>.<<<<....<<<<...........>>>>....>>>>.>>>>....>>>
>>>>......<<.......<<<<..<..>..>>>>....>>........<
<<<<....<<<<<<<<<<<<......>>>>>>>>>>>>..>>>>>.....
.....<<<<<.<.............>.....<<<<<<<<<.<<<..>>>.
...>>>>.>>>>>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8eup Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		G12 K13 L15 K17 R23 P24 S25 R26 R27 K28 G29 H30 L31 R34 R39 Y51 R74 L75 K79 R80
Binding residue
(residue number reindexed from 1)		G11 K12 L14 K16 R22 P23 S24 R25 R26 K27 G28 H29 L30 R33 R38 Y50 R73 L74 K78 R79
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8eup, PDBe:8eup, PDBj:8eup
PDBsum8eup
PubMed36423630
UniProtO94658|RL36B_SCHPO Large ribosomal subunit protein eL36B (Gene Name=rpl3602)

[Back to BioLiP]