Structure of PDB 7oie Chain i Binding Site BS01

Receptor Information
>7oie Chain i (length=97) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IGIRLTLPPPKVVDRWNEKRAMFGVYDNIGILGNFEKHPKELIRGPIWLR
GWKGNELQRCIRKRKMVGSRMFADDLHNLNKRIRYLYKHFNRHGKFR
Ligand information
>7oie Chain A (length=1472) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagcaaccuuagcc
aaaccauuuacaaauaaaguauaggcgauagaaauugauggcgcaauaga
uauaguaccgcaagggaaagaugaaaaauuauaaccaagcauaauauagc
aaggacuaaccccuauaccuucugcauaaugaauuaacuagaaauaacuu
ugcaaggagagccaaagcuaagacccccgaaaccagacgagcuaccuaag
aacagcuaagagcacacccgucuauguagcaaaauagugggaagauuuau
agguagaggcgacaaaccuaccgagccuggugauagcugguuguccaaga
uagaaucuuaguucaacuuuaaauuugcccacagaaccaaauccccuugu
aaauuuaacuguuaguccaaagaggaacagcucuuuggacacuaggaaaa
aaccuuguagagagaguaaaaaauuuaacacccauaguaggccuaaaagc
agccaccaauuaagaaagcguucaagcucaacaccaaaaaucccaaacau
auaacugaacuccucacacccaauuggaccaaucuaucacccuauagaag
aacuaauguuaguauaaguaacaugaaaacauucuccuccgcauaagccu
gcgucagauacugacaauuaacagcccaauaucuacaaucaaccaacaag
ucauuauuacccucacugucaacccaacacaggcaugcucauaaggaaag
guuaaaaaaaguaaaaggaacucggcaaaucuuaccccgccuguuuacca
aaaacaucaccucuagcaucaccaguauuagaggcaccgccugcccagug
acacauguuuaacggccgcgguuaaccgugcaaagguagcauaaucacuu
guuccuuaaauagggaccuguaugaauggcuccacgaggguucagcuguc
ucuuacuuuuaaccagugaaauugaccugcccgugaagaggcgggcauaa
cacagcaagacgagaagacccuauggagcuuuaauuuauuaaugcaaaca
guaaccugcauuaaaaauuucgguuggggcgaccucggagcagaacccaa
ccuccgagcaguacaugcuaagacuucaccagucaaagcgaaccucaauu
gauccaauaacuugaccaacggaacaaguuacccuagggauaacagcgca
auccuauucuagaguccauaucaacaauaggguuuacgaccucgauguug
gaucaggacaucccgauggugcagccgcuauuaaagguucguuuguucaa
cgauuaaaguccuacgugaucugaguucagaccggaguaauccaggucgg
uuucuaucuacuuuauuccucccuguacgaaaggacaagagaaauaaggc
cuacuucacaaagcgccuucccccguaaaugauaucaucucaacuuagau
acccacacccaagaacaggguu
<<<.......<<<<....................................
<......>.............<<.....>>.........>>.>>......
.......<<....>>......................>>>..........
.<<<.......>>>...<............>.<<<<<<.........<<<
.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....<<<<<.<
<<..<<<...>>>...<<<..<<<<........>>>>.>>>....>>>.>
>>>>...<<.......>>......>.>>>>......>.>>..<<<<<<..
..<<<<....>>>>.<<.<<<<<<<<<<.....<<......>>.....>>
>>>>>>>>..>>..<<<<<<<<<<......>>>>>>>>>>...<<<....
..>>>....<<<.<<<...<..............<....<<<........
.>>>....>.......<<<......>>>......................
.....>...>>>>>>........>>>>>>...<<<<<......>>>>>..
.......>>>>>><......<<..<<<....>>><<<<..<<<<......
..<<<<<...>>>>>......<<<...<<<<...................
....>>>>.......>>>.....<<......>>.>>>>.....>>>>..<
<<<...<<<<<<<<.<<.........<......<<<<<<..<<<......
...>>>...<<<<<<.............>>>>>>....<<<.<<<..<<<
<<....>>>..>>>>><<<<<....>>>>>........<...........
<<<<<<.....>>>>>>.....>....>>>....>>.>>>>.....>..>
>.>>>>>>>>>>>>.>>.....>.....<<<<<........>>>>>....
...<<..<<<.<<......<<<<.<<<<<<..<<<<..<<<<<<<<....
......>>>>>>>>.>>>>..<<<<.....>>>><<<<<<..........
.>>>>>>..<<.....<<<..<<<<.....>>>>..>>>....>>.....
....<<<....>>>............>>>>..>>>>>>.......<<<..
<.<<<<<<...<<.......>>...>>>>>>...>.>>.>.........<
<<.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>
>>>.....>>>>>..>...>>>.......<<<<<<<....>>>.>>>>..
..>>..>>>.>>..<<<.<<<.................>>>.>>><<<<<
...<<<....>>>.>>>>>......<<<................>>>...
......<<<<.......>>>>.
Receptor-Ligand Complex Structure
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PDB7oie A distinct assembly pathway of the human 39S late pre-mitoribosome.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		I32 I34 R35 L36 K42 R46 K50 R51 F66 K68 H69 P70 P77 R93 K94 K112 R113 R115 Y116 Y118 H120 F121 H124 G125 K126 F127
Binding residue
(residue number reindexed from 1)		I1 I3 R4 L5 K11 R15 K19 R20 F35 K37 H38 P39 P46 R62 K63 K81 R82 R84 Y85 Y87 H89 F90 H93 G94 K95 F96
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7oie, PDBe:7oie, PDBj:7oie
PDBsum7oie
PubMed34315873
UniProtQ4U2R6|RM51_HUMAN Large ribosomal subunit protein mL51 (Gene Name=MRPL51)

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