Structure of PDB 7odr Chain i Binding Site BS01

Receptor Information
>7odr Chain i (length=97) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IGIRLTLPPPKVVDRWNEKRAMFGVYDNIGILGNFEKHPKELIRGPIWLR
GWKGNELQRCIRKRKMVGSRMFADDLHNLNKRIRYLYKHFNRHGKFR
Ligand information
>7odr Chain A (length=1448) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccuc
uaaauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuug
gacacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauag
uaggccuaaaagcagccaccaauuaagaaagcguucaagcucaacacaaa
aaaucccaaacauauaacugaacuccucacacccaauuggaccaaucuau
cacccuauagaagaacuaauguuaguauaaguaacaugaaaacauucucc
uccgcauaagccugcgucagauuaaaacacugaacugacaauuaacagcc
caauaucuacaaucaaccaacaagucauuauuacccucacugucaaccca
acacaggcaugcucauaaggaaagguuaaaaaaaguaaaaggaacucggc
aaaucuuaccccgccuguuuaccaaaaacaucaccucuagcaucaccagu
auuagaggcaccgccugcuggcuccacgaggguucagcugucucuuacuu
uuaaccagugaaauugaccugcccgugaagaggcgggcauaacacagcaa
gacgagaagacccuauggagcuuuaauuuauuaaugcaaacagaaaccug
cauuaaaaauuucgguuggggcgaccucggagcagaacccaaccuccgag
caguacaugcuaagacuucaccagucaaagcgaacacucaauugauccaa
uaacuugaccaacggaacaaguuacccuagggacagcgcaauccuauucu
agaguccauaucaacaauaggguuuacgaccucguuggaucaggacaucc
cgauggugcagccgcuauuaaagguucguuuguucaacgauuaaaguccu
acgugaucugaguucagaccggaguaauccaggucgguuucuaucuacuu
ucaaauuccucccuguacgaaaggacaagagaaauaaggccuacuucaca
aagcgccuucccccguaaaugauaucaucucaacuuaguauacccacacc
cacccaagaacaggguuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuu
<<<.......<<<<....................................
.<......>...............<<.....>>.............>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>>.<<.<<<<<<<<<<.....<<......
....>>.....>>>>>>>>>>..>>..<<<<<<<<<<....[.>>>>>>>
>>>...<<<......>>>....<<<.<<<...<..............<..
..<<<.........>>>....>.......<<<......>>>.........
..................>...>>>>>>........>>>>>>...<<<<<
......>>>>>.........>>>>>><......<<..<<<....>>><<<
<..<<<<........<<<<<..............>>>>>......<<<..
.<<<<.......................>>>>.......>>>.....<<.
.....>>.>>>>.....>>>>..<<<<...<<<<<<<<.<<.........
.......<<<<<<..<<<.........>>>...<<<<<<...........
..>>>>>>....<<<....>>>....>>.>>>>........>>.>>>>>>
>>>>>>.>>.....>.....<<<<<........>>>>>.......<<..<
<<.<<<....<<<<<.<<<<<<..<<<<<.<<<<<<<<..........>>
>>>>>>>>>>>..<<<<((((.>>>><<<<<<...........>>>>>>.
.<<.....<<<..<<<<.....>>>>..>>>.....>>.........<<<
....>>>............>>>>..>>>>>>>.......<<<<<<<<<..
.<<.......>>...>>>>>>>>>]....)))).<<<<<.<<<<<<..<<
.<<<<<<......>>>>>>...>>.<<<<<.....>>>>>.....>>>>>
..>...>>>>>.....<<<<<<<....>>>.>>>>...>>>..>>>.>>.
..<.<<<.<<<.................>>>.>>><<<<<...<<<....
>>>.>>>>>......<<<................>>>...>.........
.<<<<.......>>>>................................
Receptor-Ligand Complex Structure
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PDB7odr Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
I32 G33 R35 L36 K42 R46 K50 R51 K68 H69 P70 E72 R75 W79 R93 K94 R95 K96 M97 S100 H108 K112 R113 R115 Y116 Y118 K119 H120 F121 R123 H124 G125 K126 F127
Binding residue
(residue number reindexed from 1)
I1 G2 R4 L5 K11 R15 K19 R20 K37 H38 P39 E41 R44 W48 R62 K63 R64 K65 M66 S69 H77 K81 R82 R84 Y85 Y87 K88 H89 F90 R92 H93 G94 K95 F96
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7odr, PDBe:7odr, PDBj:7odr
PDBsum7odr
PubMed34135320
UniProtQ4U2R6|RM51_HUMAN Large ribosomal subunit protein mL51 (Gene Name=MRPL51)

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