Structure of PDB 7nhk Chain i Binding Site BS01

Receptor Information
>7nhk Chain i (length=131) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VMTDPIADFLTRIRNANMVKHETLEVPASKIKRDIAEILKREGFIRDVEY
IEDDKQGVIRVFLKYGKNEERVITNLKRISKPGLRAYVKADEVPKVLNGL
GIAIISTSEGVITDKEARAKNIGGEVIAYVW
Ligand information
>7nhk Chain a (length=1517) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gagaguuugauccuggcucaggacgaacgcuggcggcgugccuaauacau
gcaagucgaacgcuucuuaagaggaguggcggacgggugaguaacacgug
gguaaccuacccaucagagggggauaacacuuggaaacaggugcuaauac
cgcauaacaguuuaugccgcauggcauaagagugaaaggcgcuggugucg
cugauggauggacccgcggugcauuagcuaguuggugagguaacggcuca
ccaaggccacgaugcauagccgaccugagagggugaucggccacacuggg
acugagacacggcccagacuccuacgggaggcagcaguagggaaucuucg
gcaauggacgaaagucugaccgagcaacgccgcgugagugaagaagguuu
ucggaucguaaaacucuguuguuagagaagaacaaggacguuaguaacug
aacguccccugacgguaucuaaccagaaagccacggcuaacuacgugcca
gcagccgcgguaauacguagguggcaagcguuguccggauuuauugggcg
uaaagcgagcgcaggcgguuucuuaagucugaugugaaagcccccggcuc
aaccggggagggucauuggaaacugggagacuugagugcagaagaggaga
guggaauuccauguguagcggugaaaugcguagauauauggaggaacacc
aguggcgaaggcggcucucuggucuguaacugacgcugaggcucgaaagc
guggggagcaaacaggauuagauacccugguaguccacgccguaaacgau
gagugcuaaguguuggaggguuuccgcccuucagugcugcagcaaacgca
uuaagcacuccgccuggggaguacgaccgcaagguugaaacucaaaggaa
uugacgggggcccgcacaagcgguggagcaugugguuuaauucgaagcaa
cgcgaagaaccuuaccaggucuugacauccuuugaccacucuagagauag
agcuuucccgggacaaagugacagguggugcaugguugucgucagcucgu
gucgugagauguuggguuaagucccgcaacgagcgcaacccuuauuguua
guugccaucauuuaguugggcacucuagcgagacugccggugacaaaccg
gaggaagguggggaugacgucaaaucaucaugccccuuaugaccugggcu
acacacgugcuacaaugggaaguacaacgagucgcuagaccgcgagguca
ugcaaaucucuuaaagcuucucucaguucggauugcaggcugcaacucgc
cugcaugaagccggaaucgcuaguaaucgcggaucagcacgccgcgguga
auacguucccgggccuuguacacaccgcccgucacaccacgagaguuugu
aacacccgaagucggugagguaaccuuuuuggagccagccgccuaaggug
ggauagaugauuggggugaagucguaacaagguagccguaucggaaggug
cggcuggaucaccuccu
..<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.<
<<..<<<..<<.<<<<....>>>>.>>>>>......<<........<<<<
<<<..<<...<<<<<<<.<.<<.....<<<<<......>>>>>......>
>.>.....<.<<<<<<<<<..>>>>>>>>>..>....<<<<<..>>>>>.
>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>>>>
>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<
.<.........>>>>>>.<<<<....>>>>...>>>>>>.........<<
<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<.
...>>>>.....>>>>...<<<<<<<.........<<<<<<<........
>>>>>>>..........>>>>>>...>..<<<<<(((...<<<<<.....
<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<(
(.....<<<<...<<<.<<<<<<<.<<<<<<<<<.......<<<<<<...
..>>>>>>.....>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<
<<....<<<<<<<<<..<<<......>>>.....>>>>>>>>>.......
....<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<
<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........
<<<<<<..<<<<<<<<<<<<<....>>>>>>>>>>>>>...<<..))>>.
....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).
]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<......
..>>..........<<<<<<<......<<<........<<<<<....>>>
>>....<<<>>>.....>.>>.<<<.<<<..<<<<<<.......<<<<<<
<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<
<..<<<..<<......>>>>>...>>>>>>>.....<<<<<.....>>>>
>........>>>>.........>>>...>>>>>>>>>...>>>>>>>...
>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>.
.>>....>>>.....>>>>>>>......<....<<<<<<<........>>
>>>>>....>.....>>>>>>....<<<<<<<.........>>>>>>>..
....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<
..<<<<...<<.<<<<..<<<..<<.....>>.>>>.>>>>.>>..>>>>
..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>
>>>>>............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7nhk Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		V2 T4 D5 D9 T12 R13 R15 N16 H22 S30 K31 K56 Q57 K82 P83 G84 R86 Y88 K90 S107 T108 S109 G111 G124 E126
Binding residue
(residue number reindexed from 1)		V1 T3 D4 D8 T11 R12 R14 N15 H21 S29 K30 K55 Q56 K81 P82 G83 R85 Y87 K89 S106 T107 S108 G110 G123 E125
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7nhk, PDBe:7nhk, PDBj:7nhk
PDBsum7nhk
PubMed34117249
UniProtA0A1B4XKS6

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