Structure of PDB 6zsb Chain i Binding Site BS01

Receptor Information
>6zsb Chain i (length=97) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IGIRLTLPPPKVVDRWNEKRAMFGVYDNIGILGNFEKHPKELIRGPIWLR
GWKGNELQRCIRKRKMVGSRMFADDLHNLNKRIRYLYKHFNRHGKFR
Ligand information
>6zsb Chain XA (length=1499) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccaa
auccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuuggac
acuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauaguag
gccuaaaagcagccaccaauuaagaaagcguucaagcucaacaccaaaaa
ucccaaacauauaacugaacuccucacacccaauuggaccaaucuaucac
ccuauagaagaacuaauguuaguauaaguaacaugaaaacauucuccucc
gcauaagccugcgucagauaacaacugacaauuaacagcccaauaucuac
aaucaaccaacaagucauuauuacccucacugucaacccaacacaggcau
gcucauaaggaaagguuaaaaaaaguaaaaggaacucggcaaaucuuacc
ccgccuguuuaccaaaaacaucaccucuagcaucaccaguauuagaggca
ccgccugcccagugacacauguuuaacggccgcgguacccuaaccgugca
aagguagcauaaucacuuguuccuuaaauagggaccuguaugaauggcuc
cacgaggguucagcugucucuuacuuuuaaccagugaaauugaccugccc
gugaagaggcgggcauaacacagcaagacgagaagacccuauggagcuuu
aauuuauuaaugcaaacaguaaccaaaccugcauuaaaaauuucgguugg
ggcgaccucggagcagaacccaaccuccgagcaguacaugcuaagacuuc
accagucaaagcgaaccucaauugauccaauaacuugaccaacggaacaa
guuacccuagggauaacagcgcaauccuauucuagaguccauaucaacaa
uaggguuuacgaccucgauguuggaucaggacaucccgauggugcagccg
cuauuaaagguucguuuguucaacgauuaaaguccuacgugaucugaguu
cagaccggaguaauccaggucgguuucuaucuacuuauuccucccuguac
gaaaggacaagagaaauaaggccuacuucacaaagcgccuucccccguaa
augauaucaucucaacuuagaauacccacacccacccaagaacaggguu
<<<.......<<<<....................................
.<<....>>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<..<<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>...>..>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
.>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>>>>
...<<<......>>>....<<<.<<<...<..............<....<
<<.........>>>....>.......<<<......>>>............
...............>...>>>>>>........>>>>>>...<<<<<...
...>>>>>.........>>>>>><......<<..<<<....>>><<<<..
<<<<........<<<<<.......>>>>>......<<<...<<<<.....
..................>>>>.......>>>.....<<......>>.>>
>>.....>>>>..<<<<...<<<<<<<<.<<.........<......<<<
<<<..<<<.........>>>...<<<<<<.............>>>>>>..
..<<<.<<<..<<<<<....>>>..>>>>><<<<<<......>>>>>>..
......<...........<<<<<<.....>>>>>>.....>....>>>..
..>>.>>>>.....>..>>.>>>>>>>>>>>>.>>.....>.....<<<<
<........>>>>>.......<<..<<<.<<......<<<<.<<<<<<..
<<<<<.<<<<<<<<...............>>>>>>>>>>>>>..<<<<..
...>>>><<<<<<...........>>>>>>..<<.....<<<..<<<<..
...>>>>..>>>....>>.........<<<....>>>............>
>>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...>>
>>>>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<<......>
>>>>>...>>.<<<<.......>>>>.....>>>>>..>...>>>.>>..
..<<<<<<<....>>>.>>>>....>>..>>>.>>.<<<.<<<.......
..........>>>.>>><<<<<...<<<....>>>.>>>>>......<<<
................>>>..............<<<<.......>>>>.
Receptor-Ligand Complex Structure
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PDB6zsb Structural basis of mitochondrial translation.
Resolution4.5 Å
Binding residue
(original residue number in PDB)		I32 I34 R35 L36 R46 K50 R51 G61 K68 H69 P70 E72 R75 P77 R93 K94 R95 K96 N111 K112 R113 R115 Y116 Y118 K119 F121 H124 G125 K126 F127
Binding residue
(residue number reindexed from 1)		I1 I3 R4 L5 R15 K19 R20 G30 K37 H38 P39 E41 R44 P46 R62 K63 R64 K65 N80 K81 R82 R84 Y85 Y87 K88 F90 H93 G94 K95 F96
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zsb, PDBe:6zsb, PDBj:6zsb
PDBsum6zsb
PubMed32812867
UniProtQ4U2R6|RM51_HUMAN Large ribosomal subunit protein mL51 (Gene Name=MRPL51)

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