Structure of PDB 6zs9 Chain i Binding Site BS01

Receptor Information
>6zs9 Chain i (length=97) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IGIRLTLPPPKVVDRWNEKRAMFGVYDNIGILGNFEKHPKELIRGPIWLR
GWKGNELQRCIRKRKMVGSRMFADDLHNLNKRIRYLYKHFNRHGKFR
Ligand information
>6zs9 Chain XA (length=1501) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccaa
aauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuugga
cacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauagua
ggccuaaaagcagccaccaauuaagaaagcguucaagcucaacaccaaaa
aucccaaacauauaacugaacuccucacacccaauuggaccaaucuauca
cccuauagaagaacuaauguuaguauaaguaacaugaaaacauucuccuc
cgcauaagccugcgucagauaaccaacugacaauuaacagcccaauaucu
acaaucaaccaacaagucauuauuacccucacugucaacccaacacaggc
augcucauaaggaaagguuaaaaaaaguaaaaggaacucggcaaaucuua
ccccgccuguuuaccaaaaacaucaccucuagcaucaccaguauuagagg
caccgccugcccagugacacauguuuaacggccgcgguacccuaaccgug
caaagguagcauaaucacuuguuccuuaaauagggaccuguaugaauggc
uccacgaggguucagcugucucuuacuuuuaaccagugaaauugaccugc
ccgugaagaggcgggcauaacacagcaagacgagaagacccuauggagcu
uuaauuuauuaaugcaaacaguaaccaaaccugcauuaaaaauuucgguu
ggggcgaccucggagcagaacccaaccuccgagcaguacaugcuaagacu
ucaccagucaaagcgaaccucaauugauccaauaacuugaccaacggaac
aaguuacccuagggauaacagcgcaauccuauucuagaguccauaucaac
aauaggguuuacgaccucgauguuggaucaggacaucccgauggugcagc
cgcuauuaaagguucguuuguucaacgauuaaaguccuacgugaucugag
uucagaccggaguaauccaggucgguuucuaucuacuuauuccucccugu
acgaaaggacaagagaaauaaggccuacuucacaaagcgccuucccccgu
aaaugauaucaucucaacuuagaauacccacacccacccaagaacagggu
u
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
..>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>>>
>...<<<......>>>....<<<.<<<...<..............<....
<<<.........>>>....>.......<<<......>>>...........
................>...>>>>>>........>>>>>>...<<<<<..
....>>>>>.........>>>>>><......<<..<<<....>>><<<<.
.<<<<........<<<<<........>>>>>......<<<...<<<<...
....................>>>>.......>>>.....<<......>>.
>>>>.....>>>>..<<<<...<<<<<<<<.<<.........<......<
<<<<<..<<<.........>>>...<<<<<<.............>>>>>>
....<<<.<<<..<<<<<....>>>..>>>>><<<<<<......>>>>>>
........<...........<<<<<<.....>>>>>>.....>....>>>
....>>.>>>>.....>..>>.>>>>>>>>>>>>.>>.....>.....<<
<<<........>>>>>.......<<..<<<.<<......<<<<.<<<<<<
..<<<<<.<<<<<<<<...............>>>>>>>>>>>>>..<<<<
.....>>>><<<<<<...........>>>>>>..<<.....<<<..<<<<
.....>>>>..>>>....>>.........<<<....>>>...........
.>>>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...
>>>>>>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<<.....
.>>>>>>...>>.<<<<.......>>>>.....>>>>>..>...>>>.>>
....<<<<<<<....>>>.>>>>....>>..>>>.>>.<<<.<<<.....
............>>>.>>><<<<<...<<<....>>>.>>>>>......<
<<................>>>..............<<<<.......>>>>
.
Receptor-Ligand Complex Structure
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PDB6zs9 Structural basis of mitochondrial translation.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		I32 I34 R35 L36 R46 R51 G61 H69 P70 E72 R75 P77 R93 K94 R95 G99 N111 K112 R113 R115 Y116 Y118 K119 H120 F121 R123 H124 G125 K126 F127
Binding residue
(residue number reindexed from 1)		I1 I3 R4 L5 R15 R20 G30 H38 P39 E41 R44 P46 R62 K63 R64 G68 N80 K81 R82 R84 Y85 Y87 K88 H89 F90 R92 H93 G94 K95 F96
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zs9, PDBe:6zs9, PDBj:6zs9
PDBsum6zs9
PubMed32812867
UniProtQ4U2R6|RM51_HUMAN Large ribosomal subunit protein mL51 (Gene Name=MRPL51)

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