Structure of PDB 5gaf Chain i Binding Site BS01

Receptor Information
>5gaf Chain i (length=398) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MFDNLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVALPVVRE
FINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPP
AVVLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLET
LAEQVGVDFFPSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEA
MMDEIKQVHASINPVETLFVVDAMTGQDAANTAKAFNEALPLTGVVLTKV
DGDARGGAALSIRHITGKPIKFLGVGEKTEALEPFHPDRIASRILGMGFD
LNDFLEQLRQMKNDDKVLVRMEAIINSMTMKERAKPEIIKGSRKRRIAAG
CGMQVQDVNRLLKQFDDMQRMMKKMKKGGPPPPPPPPPPPPPPPPPPP
Ligand information
>5gaf Chain 1 (length=43) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucuguuuaccaggucagguccggaaggaagcagccaaggcaga
<<<<<<<....<<<....<<<....>>>....>>>.>>>>>>>
Receptor-Ligand Complex Structure
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PDB5gaf Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon
Resolution4.3 Å
Binding residue
(original residue number in PDB)		A378 N381 S382 M383 T384 M385 K386 R388 S397 R398 R401 G405 C406
Binding residue
(residue number reindexed from 1)		A323 N326 S327 M328 T329 M330 K331 R333 S342 R343 R346 G350 C351
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008312 7S RNA binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0048500 signal recognition particle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5gaf, PDBe:5gaf, PDBj:5gaf
PDBsum5gaf
PubMed26804923
UniProtP0AGD7|SRP54_ECOLI Signal recognition particle protein (Gene Name=ffh)

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