Structure of PDB 7p7t Chain h Binding Site BS01

Receptor Information
>7p7t Chain h (length=153) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIYNSFDIIK
ESTGNDPLEVFEQAMKNVMPVLEVKARRVGGSNYQVPVEVRPERRTTLGL
RWVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAF
AHY
Ligand information
>7p7t Chain a (length=1521) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gagaguuugauccuggcucaggacgaacgcuggcggcgugccuaauacau
gcaagucgaacgcuucuuaagaggaguggcggacgggugaguaacacgug
gguaaccuacccaucagagggggauaacacuuggaaacaggugcuaauac
cgcauaacaguuuaugccgcauggcauaagagugaaaggcgcuggugucg
cugauggauggacccgcggugcauuagcuaguuggugagguaacggcuca
ccaaggccacgaugcauagccgaccugagagggugaucggccacacuggg
acugagacacggcccagacuccuacgggaggcagcaguagggaaucuucg
gcaauggacgaaagucugaccgagcaacgccgcgugagugaagaagguuu
ucggaucguaaaacucuguuguuagagaagaacaaggacguuaguaacug
aacguccccugacgguaucuaaccagaaagccacggcuaacuacgugcca
gcagccgcgguaauacguagguggcaagcguuguccggauuuauugggcg
uaaagcgagcgcaggcgguuucuuaagucugaugugaaagcccccggcuc
aaccggggagggucauuggaaacugggagacuugagugcagaagaggaga
guggaauuccauguguagcggugaaaugcguagauauauggaggaacacc
aguggcgaaggcggcucucuggucuguaacugacgcugaggcucgaaagc
guggggagcaaacaggauuagauacccugguaguccacgccguaaacgau
gagugcuaaguguuggaggguuuccgcccuucagugcugcagcaaacgca
uuaagcacuccgccuggggaguacgaccgcaagguugaaacucaaaggaa
uugacgggggcccgcacaagcgguggagcaugugguuuaauucgaagcaa
cgcgaagaaccuuaccaggucuugacauccuuugaccacucuagagauag
agcuuucccuucggggacaaagugacagguggugcaugguugucgucagc
ucgugucgugagauguuggguuaagucccgcaacgagcgcaacccuuauu
guuaguugccaucauuuaguugggcacucuagcgagacugccggugacaa
accggaggaagguggggaugacgucaaaucaucaugccccuuaugaccug
ggcuacacacgugcuacaaugggaaguacaacgagucgcuagaccgcgag
gucaugcaaaucucuuaaagcuucucucaguucggauugcaggcugcaac
ucgccugcaugaagccggaaucgcuaguaaucgcggaucagcacgccgcg
gugaauacguucccgggccuuguacacaccgcccgucacaccacgagagu
uuguaacacccgaagucggugagguaaccuuuuuggagccagccgccuaa
ggugggauagaugauuggggugaagucguaacaagguagccguaucggaa
ggugcggcuggaucaccuccu
..<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.<
<<..<<<..<<.<<<<....>>>>.>>>>>......<<........<<<<
<<<..<<...<<<<<<<.<.<<.....<<<<<<....>>>>>>......>
>.>.......<<<<<<<<....>>>>>>>>.......<<<<<..>>>>>.
>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>>>>
>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<
.<.........>>>>>>.<<<<....>>>>...>>>>>>.........<<
<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<.
...>>>>.....>>>>...<<<<<<<.........<<<<<<<........
>>>>>>>..........>>>>>>...>..<<<<<(((...<<<<<.....
<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<(
(.....<<<<...<<<.<<<<<<<.<<<<<<<<<.......<<<<<<...
..>>>>>>.....>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<
<<....<<<<<<<<<..<<<......>>>.....>>>>>>>>>.......
....<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<
<<<<...<<...<<<<.........>>>>...>>>>>>>>..........
<<<<<<..<<<<<<<<<<<<<....>>>>>>>>>>>>>...<<..))>>.
....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).
]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<......
..>>..........<<<<<<<......<<<<.......<<<<<....>>>
>>...<<<<<..>>>>>...>>.>>.<<<.<<<..<<<<<<.......<<
<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<
<<<<<..<<<..<<......>>>>>...>>>>>>>.....<<<<<.....
>>>>>........>>>>.........>>>...>>>>>>>>>...>>>>>>
>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>
>>>..>>....>>>.....>>>>>>>...........<<<<<<<......
..>>>>>>>..........>>>>>>....<<<<<<<.........>>>>>
>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<
<<<<..<<<<...<<.<<<<..<<<..<<.....>>.>>>.>>>>.>>..
>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....
>>>>>>>>>............
Receptor-Ligand Complex Structure
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PDB7p7t Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
P2 R3 V7 K9 R10 N28 R29 V30 M31 D33 G34 K35 G37 I38 R92 R95 T98 R102 R109 H114 M116 R119
Binding residue
(residue number reindexed from 1)
P1 R2 V6 K8 R9 N27 R28 V29 M30 D32 G33 K34 G36 I37 R91 R94 T97 R101 R108 H113 M115 R118
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7p7t, PDBe:7p7t, PDBj:7p7t
PDBsum7p7t
PubMed35387982
UniProtA0A1B4XKQ3

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