Structure of PDB 7oqe Chain h Binding Site BS01

Receptor Information
>7oqe Chain h (length=107) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKLVNFLKKLRNEQVTIELKNGTTVWGTLQSVSPQMNAILTDVKLTLPQS
NGIAMASLYLTGGQQNIASLQYINIRGNTIRQIILPDSLNLDSLLVDQKQ
LNSLRRS
Ligand information
>7oqe Chain 1 (length=558) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auacuuaccuuaagauaucagaggagaguccuacugaucaaacaugcgcu
uccaauaguagaaggacguuaagcauuuaucauugaacuauaauuguuca
uugaagucauugaugcaaacuccuuggucacacacacauacggcgcggaa
ggcguguuugcugacguuuccauucccuuguuucaaucauugguuaaucc
cuugauuccuuuggggauuuuuggguuaaacugauuuuuggggcccuuug
uuucuucugccuggagaaguuugacaccaaauucaaauugguguuagggg
agcuggggccuuucaaaagagagcuuuguagaggcauucuuuuugacuac
uuuucucuagcgugccauuuuaguuuuugacggcagauucgaaugaacuu
aaguuuaugaugaagguauggcuguugagauuauuuggucgggauuguag
uuugaagaugugcucuuuugagcagucucaacuuugcucguucccguuau
gggaaaaauuuuggaaggucuugguaggaacggguggaucuuauaauuuu
ugauuuau
...........<<<<.<<<<<<<<<...>>>>.>>>>><<<<<<<<<.<<
<<<........<<<<<.<<<..<<<<.<.<<<.<<<<<.......>>>>>
.>>>.......>>>>>.>>>>>>>>.....................>>>>
>>>>>>>>>><<<.<<<<.<<..<<<<<.<<<<<<<..<<<<<<<.<.<<
<..<<<<<<<..>>>>>>>...>>>.>.>>>>>>>..>>>>>>>((....
...<<<<<....))>>>>>...<<<<<<<<.......>>>>>>>>.>>>>
><<<<<<<<<<<<<<<<<..<<<<...<<.<<<<...<<<<<..<<<<<<
..<<<<.......<<<<...<<<<<<<.<<<<<<...<<<<.<<<<<<..
..>>>>>>..>>>>......>>>>>>>>>>>>>..>>>>.>>>>..>>>>
>>.>>>>>..<<<<<....>>>>>.>>>>.>>...>>>>.<<<<<<...>
>>>>>...>>>>>>>>>>>>>>>>>.>>>>>>..>>>.>>>>........
........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7oqe Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Resolution5.9 Å
Binding residue
(original residue number in PDB)		P34 N90 R117
Binding residue
(residue number reindexed from 1)		P34 N78 R105
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000387 spliceosomal snRNP assembly
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0036261 7-methylguanosine cap hypermethylation
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005682 U5 snRNP
GO:0005685 U1 snRNP
GO:0005686 U2 snRNP
GO:0005687 U4 snRNP
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0030532 small nuclear ribonucleoprotein complex
GO:0034715 pICln-Sm protein complex
GO:0034719 SMN-Sm protein complex
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP
GO:0071004 U2-type prespliceosome
GO:0071011 precatalytic spliceosome
GO:0071013 catalytic step 2 spliceosome
GO:0097525 spliceosomal snRNP complex
GO:0097526 spliceosomal tri-snRNP complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7oqe, PDBe:7oqe, PDBj:7oqe
PDBsum7oqe
PubMed34349264
UniProtQ02260|SMD1_YEAST Small nuclear ribonucleoprotein Sm D1 (Gene Name=SMD1)

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