Structure of PDB 6spf Chain h Binding Site BS01

Receptor Information
>6spf Chain h (length=129) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMQDPLADMLTRIRNAQMAEKTVVSMPSSKLKAAVAKVLKDEGYIADFQI
SSEVKPQLSIELKYFEGKPVIEEVKRISRPGLRQYKSVEQLPAVRGGLGV
SIVSTNKGVMTDRAARAAGVGGEVLCTVF
Ligand information
>6spf Chain a (length=1390) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaagaguuugaucauggcucagauugaacgcuggcggcaggccuaacaca
ugcaagucgagcggaugaagggagcuugcuccuggauucagcggcagacg
ggugaguaaugccuaggaaucugccugguagugggggauaacguccggaa
acgggcgcuaauaccgcauacguccugagggagaaagugggggaucuucg
gaccucacgcuaucagaugagccuaggucggauuagcuaguugguggggu
aaaggccuaccaaggcgacgauccguaacuggucugagaggaugaucagu
cacacuggaacugagacacgguccagacuccuacgggaggcagcaguggg
gaauauuggacaaugggcgaaagccugauccagccaugccgcgugucuuu
aaguugggaggaagggcaguaaguuaauaccuugcuguuuugacguuacc
aacagaauaagcaccggcuaacuucgugccagcagccgcgguaauacgaa
gggugcaagcguuaaucggaauuacugggcguaaagcgcgcguagguggu
ucagcaaguuggaugugaaauccccgggcucaaccugggaacugcaucca
aaacuacugagcuagaguacgguagagggugguggaauuuccuggaagga
acaccaguggcgaaggcgaccaccuggacugauacugacacugaggugcg
aaagcguggggagcaaacaggauuagauacccugguaguccacgccguaa
acgaugucgacuagccguugggauccuugagaucuuaguggcgcagcuaa
cgcgauaagucgaccgccuggggaguacggccgcaagguuaaaacucaaa
ugaauugacgggggcccgcacaaugcugagaacuuuccagagauggauug
gugccuucgggaacucagacacaggugcugcauggccagcucgugucgug
agauguuggguuaagucccguaacgagcgcaaccuccuuaguuaccagca
ccucgggugggcacucuaaggagacugccggugacaaaccggaggaaggu
gucaagucaucauggcccuuacggccagggcuacacacgugcuacaaugg
ucgguacaaaggguugccaagccgcgagguggagcuaaucccauaaaacc
gaucguaguccggaucgcagucugcaacucgacugcgugaagucggaauc
gcuaguaaucgugaaucagaaugucacggugaauacguucccgggccuug
uacacaccgcccgucacaccaugggaguggguugcuccagaaguagcuag
ucuaaccgcaagggggacgguuaccacggagugauucaugacugggguga
agucguaacaagguagccguaggggaaccugcggcuggau
...<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.
<<<..<<<..<<.<<<...<..<<<..>>>..>..>.>>.>>>>>.....
.<<.......<<<<<<<..<<...<<<<<<<<<.<<.....<<<<<<...
.>>>>>>......>>.>.....<<<....>>>....<<<<<<..<<....
>>>>>>>>>>>>>>>>..>>.>>>>>>><<<....<<<...<<<<<<<..
.....>>>>>>>.>>>......>>>..<<<<<<<<....>>>>...>>>>
.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>..
.......<<<....<<<<....>>>>..>>>..>>.>>>>>>........
..<<<<<......<<<..<..<<........>>..>..>>>.......>>
>>>.......<<<<<((.....<<<<.....<<..))>>.......>>>>
.>>>>>..>>>>>>>>>..........<<<((.....<<<<...<<<.<<
<<<<..<<<<<<<<<<......<<<<<<.....>>>>>>....>>>>>>>
>..>>.>>>>>>...<<<<<<<....<<<<<<<.....<<<<.>>>>...
.........<<....>>.>>>>>>>...>>>.>>>>...>>>...>>>>.
...<<<<<<<...<...<<<<.........>>>>...>>>>>>>>.....
.....<<<<<<..<<<<<<<<<<<<.....>>>>>>>>>>>>...<<..)
)>>.....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)
))).]<<<<<.<<<<<<<.<<....<<<.........<.......>....
...<......>....>>>.........<..........<<<<<<<<<...
.>>>..<<<<......>>>>..>>>>>>....................<<
.......>>..................<<<<<.....>>>>>........
.............>....................................
..................................................
..................................................
....................................>>...>>>>>>>>>
>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<....<<<<<<.<
<<<..<<....>>.>>>>>>>>>>...>>>>>>>>>>>>..>>>.>>>>.
.>.>>...>.....<<<<<<<<<....>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6spf Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Resolution2.89 Å
Binding residue
(original residue number in PDB)		S2 Q4 P6 D9 T12 R13 R15 N16 M19 A20 K22 S30 K31 L32 K56 R80 P81 R84 Y86 S88 V89 S105 T106 N107 G120 V121 G122 E124
Binding residue
(residue number reindexed from 1)		S1 Q3 P5 D8 T11 R12 R14 N15 M18 A19 K21 S29 K30 L31 K55 R79 P80 R83 Y85 S87 V88 S104 T105 N106 G119 V120 G121 E123
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6spf, PDBe:6spf, PDBj:6spf
PDBsum6spf
PubMed31611393
UniProtE2RXT9

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