Structure of PDB 5opt Chain h Binding Site BS01

Receptor Information
>5opt Chain h (length=173) Species: 353153 (Trypanosoma cruzi strain CL Brener) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NGLYVKNWGQGSVDDARALFGTAGKVVGVRVRRRRYAIIFFENAAAVKKA
IDLFNGKEFMGNVLSVVPAKTTPKPDPHANSSVVFVSPIFRASTTKKQIL
ELFSGMKVLRLRTYRNNYAYVYLDTPAAAQRAVKEKNGAEFRGKQLRVAL
STRSLAKDRARAERARLLMAAQK
Ligand information
>5opt Chain E (length=2022) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaucugguugauucugccaguagucauaugcuuguuucaaggacuuagcc
augcaugccucagaaucacugcauugcaggaaucugcgcauggcucauua
caucagacguaaucugccgcaaaaaucuugcggucuccgcaacauuggau
aacuuggcgaaacgccaagcuaauacaugaaccaaccggauguucucugu
uccggcggcagggcaaccugcugccaugggacguccagcgaaugaaugaa
aguaaaaccaaugccuucaccggcaguaacacucagaaguguugauucaa
uucauuccgugcgaaagccggguuuuuuuauccggcgucuuuugacgaac
aacugcccuaucagccagcgauggccguguaguggacugccauggcguug
acgggagcgggggauuaggguucgauuccggagagggagccugagaaaua
gcuaccacuucuacggagggcagcaggcgcgcaaauugcccaaugucaaa
aaaaaaagaugaggcagcgaaaagaaauagagccgacagugcuuuugcau
ugucguuuucaaugggggauauuuaaacccauccaaaaucgaguaacaau
uggaggacaagucuggugccagcacccgcgguaauuccagcuccaaaagc
guauauuaaugcuguugcuguuaaaggguucguaguugaauugagggccu
cuaaggcgcaaugguuuagucccauccacuucggauuggugacccaugcc
cuugugguccgugaacgacauucagaaacaaaaaacacgggagugguacc
uuuccugauuaucgcaugucaugcaugccagagggcgcccgugauuuuuu
acugugacuaaaaaagugugaccaaagcagucauucgacuugaauuagaa
agcaugggauaacaaaggagcagccucugggccaccguuucggcuuuugu
ugguuuuaaaaguccauuggagauuauggggcagugugacaagcggcugu
cgccuuugugggaaaugccuucccucaacucacggcauccaggaaugaag
gaggguaguucgggggagaacguacuggugcgucagaggugaaauucuua
gaccgcaccaagacgaacuacagcgaaggcauucuucaaggauaccuucc
ucaaucaagaaccaaaguguggggaucgaagaugauuagagaccauugua
guccacacugcaaacgaugacacccaugaauuggggacucagcacguuau
cugacuucuucacgcgaaagcuuugagguuacagucucaggggggaguac
guucgcaagagugaaacuuaaagaaauugacggaauggcaccacaagacg
uggagcgugcgguuuaauuugacucaacacggggaacuuuaccagauccg
gacagggugaggauugacagauugaguguucuuucucgauccccugaaug
guggugcauggccgcuuuuggucgguggagugauuuguuugguugauucc
gucaacggacgagauccaagcugcccaguaggauucagaauugcccaucc
cuuccgcggguuuuacccaagggggggcgguauucgcuuguauccuucuc
ugcgggauuccuuguuuugcgcaaggugagauuuugggcaacagcagguc
ugugaugcuccucaauguucugggcgacacgcgcacuacaaugucaguga
gaacaagaaaaacgacucuugucggaccuacuugaucaaaagagugggaa
aaccccggaaucacguagacccacuugggaccgaguauugcaauuauugg
ucgcgcaacgaggaaugucucguaggcgcagcucaucaaacugugccgau
uacgucccugccauuuguacacaccgcccgucguuguuuccgaugauggu
gcaauacaggugaucggacagucgagugcuucacuugaccgaaaguucac
cgauauuucuucaauagaggaagcaaaagucguaacaagguagcuguagg
ugaaccugcagcuggaucauuu
...<<<<....{{{{.>>>>{{{{.[[[[[[...[[[..........[[[
.[[[..<<....<<....<<<<...>>>>...>>.>>......{{.....
...[[[..[[..[[...[[.[[.....<<<<<<...>>>>>>...<<...
..<<<<<<.....>>>>>>......>>..........<<<<<.<<<....
...<<<<<<<<<....>>>>>>>>>...>>>>>>>>.[[((((((((...
...<<<<<<<<<<<<......>>>.........................)
)))))))...]]....<<<<<<........>>>>>>...]].]]..]]]]
..]]].<<<....<<<....<<<<<.<<.......>>.>>>>>>>>....
..>>>..<<<.<<<<....>>>>....>>>.}}.<<.<<<..........
>>>.>>.<<<<....>>>>...]]]]]].........<<<....<<<...
.......>>>..>>>.......]]]....<<<.<<<<<<<<<....>>>>
>>>>>..>>>.....<<<<............>>>.....>.........<
<<<<((......<<<<.....<<..))>>.......>>>>.>>>>>..]]
]]]]}}}}.........{{{{{.....[[[[...[[[..{....<<<<<.
<.<<<<.<<<.<<<.............................>>>>>>>
>>>>.>>>>>.........................<<<<<<.......<<
<<<............<<.......>>....>>>>>..>>>>>>.....<<
<<<<<<.......<<...<.......>..<<<....>>>.....>>....
..>>>>>..>>>...........[[..(((((..<<.....>>.....>>
>>>>>>>....)))))..]].......<<<.<.<<<.<.....<<<...>
>>........<<<......>>>......>.>>>.>..>>>.....}....
..<<<<<..<<...<<<<<<<<..<<<<<<<<...<<<......>>>...
...>>>>>>>.>.>>.......<<....>>.>>>>>>..>>.>>>.>>..
..]]]...]]]]...<<<<<<<<...<...<<<<.........>>>>...
>>>>>>>>>.........<<<.<<...<..<<<<<..............>
>>>>..>......<<..}}>>.....>>.....>>>.}}}.<<<......
<<<<....>>>>....>>>..}}}}..<<<<<.<<<<<<<..<<.<<<<<
<.....<<<<<........<<........>>..........<<.<<....
..<<<<<........<<.<<<........>>>.>>......>>>>>...<
<.<<<.....<<<<<<....<<<.<<<<<....>>>...<<<......>>
>...>>.>>>....<<<<<.<<<<.....<<<<<....<.........<.
<<<<<..<<<.....>>>..>>>>>.>......>.......>>>>>....
.>>>>...<..<.<<.....>>>..>.......>>>>>....>>>.>>>.
......>>>>>.......>.>.>>.......>>>>>..............
..........................<<<<<<<........>>>>>>>..
..........................<....<<<................
>>>.....>.....>>>>>>....<<<<<<<.........>>>>>>>...
...>>...>>>>>>>>>>.>>....<..<<.<.<<<<<<<<..<<.<<<.
<.<<<<..<<<<<.<...<.<<<<<<<<...>>>>>>>>.>...>.>>>>
>..>>>>.>.>>>.>>..>>>>>>>>..>.>>...>.....<<<<<<<<<
....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5opt The cryo-EM Structure of a Novel 40S Kinetoplastid-Specific Ribosomal Protein.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		G69 Y71 R99 I105 F107 E109 V114 K115 I118 A136 K137 T138 F152 F157 R158 A159 S160 K174 R177 R179 T180 Y181 R182 N183 G210 S218 K224 A229 M236
Binding residue
(residue number reindexed from 1)		G2 Y4 R32 I38 F40 E42 V47 K48 I51 A69 K70 T71 F85 F90 R91 A92 S93 K107 R110 R112 T113 Y114 R115 N116 G143 S151 K157 A162 M169
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5opt, PDBe:5opt, PDBj:5opt
PDBsum5opt
PubMed29107485
UniProtQ4DY32

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