Structure of PDB 4ce4 Chain h Binding Site BS01

Receptor Information

>4ce4 Chain h (length=272) Species: 9825 (Sus scrofa domesticus)

PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPDYHAEIQAFGHRLQETFS
LDLLKTAFVNSCYIKSEEAKRQKLGIDKEAALLNLKDNQELSEQGISFSQ
TCLTQFFEDAFPDLPTEGVTSLVDFLTSEEVVCHVARNLAVEQLALSAEF
PVPPPVLRQTFFAVIGALLQSSGPERTALFIRDFLITQMTGKELFEMWTI
TNPMGLLVEELKKRKISAPESRLTRQSGSTTALPVYFVGLYCDRKLIAEG
PGETVLVAEEEAARVALRKLFG

Ligand information

>4ce4 Chain A (length=1444)

accaaagcuagcucaacauuuuuuuuaaauaaaauaaaacauucaccuaa
cauuaaaguauaggagauagaaauuuuuauccugacgcuauagagauagu
accguaagggaaagaugaaagaauaaaauaaaaguaaaaaaaagcaaaga
uuaccccuucuaccuuuugcauaaugguuuaaccagaaaaaaucuaacaa
agagaacuuuagcuagauaccccgaaaccagacgagcuacccaugagcag
uuuaaaagaaccaacucaucuauguggcaaaauagugagaagacuuguag
guagaggugaaaagccuaacgagccuggugauagcugguuguccgagaaa
gaauuuuaguucaaccuuaaaaauaccccaaaaauuccaauguauuuuua
agagauagucuaaaaagguacagcuuuuuagaaacggauacaaccuugac
uagagaguaaaucuuaauacacauaaucccaaaaaaacaaacuccuagcc
caauaccggacuaaucuauugaaacauagaagcaauaauguuaauaugag
uaacaagaagccuuucuccucgcacacgcuuacaucaguaacuaauaaua
uacugauaauuaacaaccaauaaaccaaaacaacacuaaaacguuuauua
auuacauuguuaacccaacacaggagugcaccaaggaaagauuaaaagaa
guaaaaggaacucggcaaacacaaaccccgccuguuuaccaaaaacauca
ccucuagcauuacuaguauuagaggcaaugccugcccagugacaccaguu
uaacggccgcgguauucugaccgugcaaagguagcauaaucacuuguucu
ccaaauaaggacuuguaugaauggccacacgaggguuuuacugucucuua
cuuccaaucagugaaauuaaccuucccgugaagaggcgggaauaaaaaaa
uaagacgagaagacccuauggagcuuuaauuaacuauuccaaaaguuaaa
cuuaacauggacuagcaauuucgguuggggugaccucggaguacaaaaaa
cccuccgagugauuuuaaucuagacaaaccagucaaaauaacccaucacu
uauugauccaaaauuuugaucaacggaacaaguuacccuagggauaacag
cgcaauccuguucuagaguuccuaucgacaauaggguuuacgaccucgau
guuggaucaggacacccaaauggugcagccgcuauuaaagguucguuugu
ucaacgauuaaaguccuacgugaucugaguucagaccggagcaauccagg
ucgguuucuaucuauuauaaauuucucccaguacgaaaggacaagagaaa
ugggaccaaccucacaaacgcgucucagagauaauuaaugauuuaaucuu
aaccuaauuaacucauaauaaauccagcccuagaacagggcaca

.........<<<<<.....................<......>.......
..........<<.....>>..............>>.>>>...........
.<<....>>.....................................<<<.
......>>>...<............>..<<<<<........<<<<<.<..
<<....>>...>.>>>>>..<<.<...<<<<.<.....<<<.<<<<<..<
<<<....>>>>...<<<..<<<<........>>>>.>>>....>>>>>.>
>>...<<<.....>>>......>.>>>>......>.>>..<<<<<.....
<<<<....>>>>..<<<<<<<<<<<<.....<<.>>.....>>>>>>>>>
>>.>....<<<<<<<<<......>>>>>>>>>...<<......>>....<
<<<.<<<..................................>>>>>>>..
......>>>>>...<<<<<......>>>>>.........>>>>>.<....
..<<..<<<<..>>>><<<..<<<<........<<<<<....<<....>>
..>>>>>......<<<..<<<<<<<.................>>>>>>>.
......>>>.....<<......>>.>>>>.....>>>..<<<<....<<<
<<<<.<<...............<<<<<<<<..<<<.........>>>...
<<<<<<.............>>>>>>....<<<.<<<..<<<<<....>>>
..>>>>><<<<<<......>>>>>>........<...........<<<<<
.......>>>>>.....>....>>>....>>.>>>>>>......>>.>>>
>>>>.>>>>.>>.....>.....<<<<<........>>>>>.......<<
<.<<<.<<......<<<<.<<<<<<..<<<<..<<<.<<<<.<<<<...>
>>>....>>>>.>>>.>>>>..<<<<.....>>>><<<<<<.........
..>>>>>>.<<<<....<<.<.<<<......>>>.>.>>.....>>>>..
........<<<....>>>............>>>>..>>>>>>.......<
<<....<<<<<<...<<.......>>...>>>>>>.....>>.>......
.<.<<<.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<...
..>>>>>.....>>>>>..>...>>>..>....<<<.<<<....>>>..>
>>....>>..>>>>>>.<<.<<<<<<<.................>>>>>>
><<<<<...............>>>>>.<<<.....<..............
......>....>>>.>>.........<<<<.......>>>>...

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4ce4 Architecture of the Large Subunit of the Mammalian Mitochondrial Ribosome.
• Resolution: 4.9 Å
• Binding residue (original residue number in PDB): X35 X38
• Binding residue (residue number reindexed from 1): X1 X4

Gene Ontology

Molecular Function

• GO:0003725 double-stranded RNA binding
• GO:0004525 ribonuclease III activity

Biological Process

• GO:0006396 RNA processing

External links

• PDB: RCSB:4ce4, PDBe:4ce4, PDBj:4ce4
• PDBsum: 4ce4
• PubMed: 24362565
• UniProt: F1SR64