Structure of PDB 7oyc Chain g2 Binding Site BS01

Receptor Information
>7oyc Chain g2 (length=310) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QMTLRGTLKGHNGWVTQIATTPQFPDMILSSSRDKSVIMWKLTRDETNYG
VPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVG
HTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTVQEESHSEWVSC
VRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHSGYLNTVTVSPD
GSLCASGGKDGQAMLWDLNEGKHLYTLDSGDVINALCFSPNRYWLCAATG
PSIKIWDLEGKIIVDELKQEVISSSSKAEPPQCTSLAWSADGQTLFAGYT
DNLIRVWQVT
Ligand information
>7oyc Chain 22 (length=1495) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcacguguaaguacgcacggagugaaacugcgaauggcucauuaaauca
guuaugguuccuuugaucacuuggauaacugugguaauucuagagcuaau
acauggcauuuaucaguggugacucuagauaaccgccgaucgcacgcacg
gcgacgauacauucggaugucugcccuaucaacuuucgaugguacuuucu
gcgccuaccauggugaccacggguaacggggaaucaggguucgauuccgg
agagggagccugagaaacggcuaccacauccaaggaaggcagcaggcgcg
caaauuacccacucccgacgcggggagguagugacgaaaaauaacaauuu
ggaaugaguacacuuuaaauccuuuaacgaggaucuauuggagggcaagu
cuggugccagcagccgcgguaauuccagcuccaauagcguauauuaaagu
ugcugcaguuaaaaagcucguaguuggaucuuguuuacuuugaaaaaauu
agaguguuccaagcaggccgccuggauacuucagcuaggaauaauggaau
aggacuccggggccaugauuaagagggacggccgggggcauucguauugu
gccgcuagaggugaaauucuuggaccggcgcaagacgaaccaaagcgaaa
gcauuugccaagaauguuuucauuaaucaagaacgaaagucggagguucg
aagacgaucagauaccgucguaguuccgaccauaaacgaugccgacuagc
gauccggcggcguuagacccgccgagcagcuuccgggaaaccaaagucuu
uggguuccggggggaguaugguugcaaagcugaaacuuaaaggaauugac
ggaagggcaccaccaggaguggagccugcggcuuaauuugacucaacacg
ggaaaccucacccggcccggacaauugacagauuucucgauucugugggu
gguggugcauggccguucuuaguugguggagcgauuugucugguuaauuc
cgauaacgaacgagacuccuccaugcuaacuaguuacgcgaccggucggc
guaacuucuuagagggacaaguggcguucagccacacgagaucgagcaau
aacaggucugugaugcccuuagauguccggggcugcacgcgcgcuacacu
gaacggaucagcguguccugcgccgacaggugcggguaacccgcugaacc
ccguucgugauagggaucggggauugcaauuauuucccaugaacgaggaa
uucccaguaagugcgggucauaagcucgcguugauuaagucccugcccuu
uguacacaccgcccgucgcuacuaccgauuggaugguuuagugagguccu
cggaucggcgccgagaagacgaucaaacuugacuaucuagaggaaguaaa
agucguaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<.........<<<.
<<<..<<....<.....<<...>>....>.>>......<<........<<
<.<<<..<<....<<<<<...<<.....<<.<<<.....>>>.>>.....
.>>..<<..<<<<<...<......>..>>>>>..>>...<<<<.<<..>>
>>>>.>>>.>>...>>>>>.>>>.<<<....<<<....<<<<<<......
.....>>>>>>>>>......>>>...<<<.<<<<....>>>>....>>>.
>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>>>...
......<<<....<<<<...>>>>..>>>......>>.>.....<<<.>>
>......<<..<...........>..>>.........<<<<<((......
<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>.>>>....
.....<.<((.....<.<<...<<<.<<......<<<<<<.<.......<
<...<.......>.<<<<.>>>>...>>......>.>>>..>>>......
..<.<<<..>>>.>....>>....<<<<<<..<...<<<<..<<..<<<<
<<<<...<<<......>>>......>>>>>>>.>.>>.......<<....
>>...>>>>..>..>>>.>>>...>>>...>>.>....<<<<<<<...<.
..<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<
..<.<<<<<<.<<<.>>>>>>>>>.>..>>>...<<..))>>...>>...
..>>>.>.>.<<<......<<<......>>>....>>>..)))).]<<<<
<.<<<<<<<..<<..<<<<<..<<<.<<<<<<......<<........>>
..........<<<<<......<....<<......>>..........>...
<<.<<<..<<<<<<<<.....<<<.<<<<<....>>>...<<<......>
>>...>>.>>>....<<<..<<...<<<<..<<<<<<<<<<<..>>>.>>
>>>>>>..>>>>..>>....<<<<<.....>>>>>........>>>....
.>>.>>>...>.>>>>>>>.......>>>>>...>>.>>>>.>>>.....
<<<<<<........<.<<<<<<<<....>>>>>>>>....>.........
>>>>>>......<.....<<<<<..........>>>>>.....>.....>
>>>>.....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>
>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.<
<...<<<<<>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>..
.>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7oyc A molecular network of conserved factors keeps ribosomes dormant in the egg.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		N15 G61 S63 H64
Binding residue
(residue number reindexed from 1)		N12 G58 S60 H61
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005080 protein kinase C binding
GO:0016301 kinase activity
GO:0043022 ribosome binding
GO:0045182 translation regulator activity
Biological Process
GO:0001934 positive regulation of protein phosphorylation
GO:0006417 regulation of translation
GO:0016310 phosphorylation
GO:0072344 rescue of stalled ribosome
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005840 ribosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7oyc, PDBe:7oyc, PDBj:7oyc
PDBsum7oyc
PubMed36653451
UniProtQ8AVP6

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