Structure of PDB 7oyb Chain g2 Binding Site BS01

Receptor Information
>7oyb Chain g2 (length=310) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QMTVRGTLKGHSGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYG
IPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVG
HTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDDSHTEWVSC
VRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPD
GSLCASGGKDGQAMLWDLNEGKHLYTLDGGDTINALCFSPNRYWLCAATG
PSIKIWDLEGKIIVDELRQDIITTNSKAEPPQCTSLAWSADGQTLFAGYT
DNLIRVWQVT
Ligand information
>7oyb Chain 22 (length=1502) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguaauauaugcuugucucaaagauuaagcca
ugcaagucuaagugcacacgagugaaacugcgaauggcucauuaaaucag
uuaugguuccuuugaucacuuggauaacuguggcaauuccagagcuaaua
caugcgccgcgugcauuuaucaguggugacucuagauaacgccgaucgcg
cgcgcggcgacgguucauucgaaugucugcccuaucaacuuucgauggua
gguccgucgccuaccauggugaccacgggugacggggaaucaggguucga
uuccggagagggagccugagaaacggcuaccacauccaaggaaggcagca
ggcgcgcaaauuacccauuuccgacacggagagguagugacgaaaaauaa
caauuuggaaugagugcaucccaaacccaugggcgaggacccauuggagg
gcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaugc
uaacguugcugcaguuaaaaagcucguaguuggaucucuuuacuuugaaa
aaauuagaguguucaaggcagggccccccauugaauaccccagcuaggaa
uaauggaauaggaccccggggccaugaucgagagggacggccgggggcau
ucguauugcgccgcuagaggugaaauucuuggaccggcgcaagacggacc
ggagcgaaagcguuugccaagaacguuuucauuaaucaagaacgaaaguc
ggagguucgaagacgaucagauaccgucguaguuccgaccguaaacgaug
ccgacccgcgauccggcggcguuugacccgccgggcagcguugcgggaaa
ccacgagucucugggcuccggggggaguaugguugcaaagcugaaacuua
aaggaauugacggaagggcaccaccaggaguggagccugcggcuuaauuu
gacucaacacggggaaccucacccggcccggacaauugacagauucucga
uucugugggugguggugcauggccguucguaguugguggagcgauuuguc
ugguugauuccgauaacgaacgagacucuggcaugcuaacuaguuacgcg
gccggucggcguaacuucuuagagggacaaguggcguucagccacgcgag
acugagcaauaacaggucugugaugcccuuagauguccggggcugcacgc
gcgccacaaugggcggaucaacguguccugcgccgacaggcgcggguaac
ccguugaaccccgcccgugauggggaccgauugaaacuauuucccgagaa
cgaggaauucccaguaagcgcaggucaucagcuugcguugauuaaguccc
ugcccuuuguacacaccgcccgucgcuacuaccgauugagcggcucagug
agguccucggaucggcgccgagaagacgaucgaacucggucguuuagagg
aaguaaaagucguaacaagguuuccguaggugaaccugcggaaggaucau
ua
...<<<<<.[.((((>>>>><<.<<<<<<<...<.<<..<......<<<.
<<<..<<....<<.............>>.>>......<<........<<<
.<<<..<<....<..<....<<.....<<.<<<.....>>>.>>......
>>..............<<<<<...<......>..>>>>>......<<<..
<....>.>>>..>...>...>>>>>.>>>.<<<....<<<.....<<<<<
<<.......>>>>>>>.>>>......>>>...<<<.<<<<....>>>>..
..>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>
>>>.........<<<....<<<.....>>>..>>>..>...>>.>.....
<<...>>......<<.<<<.........>>>.>>.........<.<<<((
......<<<......<<..))>>........>>>.>>>.>..>>>>>>>.
>>.........<.<((.....<.<<...<<<.<<.....<<<<<<.<...
....<<...<.......>...<<...>>.......>>......>.>>>..
>>>..........<<<..>>>......>>....<<<<<<..<...<<<<.
.<<..<<<<<<<<...<<<......>>>......>>>>>>>.>.>>....
...<<....>>...>>>>..>..>>>.>>>...>>>...>>.>....<<<
<<<<...<...<<<<.........>>>>...>>>>>>>>..........<
<<.<<.<<<..<<<<<<<<.<<<.>>>>>>>>>>>..>>>....<<..))
>>....>>.....>>>.>.>.<<<......<<<......>>>....>>>.
.)))).]<<<<<.<<<<<<<..<<..<<<<<....<<............<
<........>>..........<<.<<...........<<.....>>....
........<.<..<<<..<<.<<<<<<....<<<.<<<<<....>>>...
<<<......>>>...>>.>>>....<<<...<...<<<<..<<<<..<<<
<<..>>>.>>..>>>>..>>>>..>.....<<<<<.....>>>>>.....
...>>>....>>>.>>>.....>>>>>.>>......>>.>>.........
>.>.......<<<<<<........<.<<<<<<<<....>>>>>>>>....
>.........>>>>>>............<<..........>>........
......>>>>>.....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>>>>.>>.......<<.<..<<<<.<<....<<<<<<<<.<<<.
.<<<<.<<...<<<<..>>>>...>>.>>>>..>>>.>>>>>>>>...>>
.>>>>...>.>>.........<<<<<<<<<<..>>>>>>>>>>.......
..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7oyb A molecular network of conserved factors keeps ribosomes dormant in the egg.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
G61 H64 R100
Binding residue
(residue number reindexed from 1)
G58 H61 R97
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005080 protein kinase C binding
GO:0043022 ribosome binding
GO:0045182 translation regulator activity
Biological Process
GO:0001525 angiogenesis
GO:0006417 regulation of translation
GO:0030178 negative regulation of Wnt signaling pathway
GO:0032880 regulation of protein localization
GO:0051302 regulation of cell division
GO:0060027 convergent extension involved in gastrulation
GO:0072344 rescue of stalled ribosome
GO:2000114 regulation of establishment of cell polarity
GO:2000543 positive regulation of gastrulation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7oyb, PDBe:7oyb, PDBj:7oyb
PDBsum7oyb
PubMed36653451
UniProtO42248|GBLP_DANRE Small ribosomal subunit protein RACK1 (Gene Name=gnb2l1)

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