Structure of PDB 8cqw Chain g Binding Site BS01

Receptor Information
>8cqw Chain g (length=60) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKVHGSLARAGKVKSQTPKVEKQEKPKKPQGRAYMRLLYTRRFVNVTLTN
GKRKMNPSPA
Ligand information
>8cqw Chain B (length=1741) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguacccuacuuggauaaccguggu
aauucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggaugu
auuuauuagauaaaaaaucaaugccuucgggcucuuugaugauucauaau
aacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaauuuc
ugcccuaucaacuuucgaugguaggauaguggccuaccaugguuucaacg
gguaacggggaauaaggguucgauuccggagagggagccugagaaacggc
uaccacauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacac
ggggagguagugacaauaaauaacgauacagggcccuuuugggucuugua
auuggaaugaguacaauguaaauaccuuaacgaggaacaauuggagggca
agucuggugccagcagccgcgguaauuccagcuccaaaagcguauauuaa
aguuguugcaguuaaaaagcucguaguugaaccuugggcuuggcuggccg
ggcguacuggacccagccgagccuuuccuucuggguagccgaaccaggac
uuuuacuuugaaaaaauuagaguguucaaagcaggccuuugcucgaauau
auuagcauggaauaauagaauaggacguuaugguucuauuuuguugguuu
cuaggaccaucguaaugauuaauagggacggucggggguaucaguauuca
guugucagaggugaaauucuuggauuuacugaagacuaacuacugcgaaa
gcauuuaccaaggacguuuucauuaaucaagaacgaaaguuaggggaucg
aagaugaucagauaccgucguagucuuaaccauaaacuaugccgacuagg
gaucgguuguuguucuuuuauugacgcaaucggcaccuuacgagaaauca
aagucuuuggguucuggggggaguauggucgcaaggcugaaacuuaaagg
aauugacggaagggcaccaccaggaguggagccugcggcuuaauuugacu
caacacggggaaacucaccagguccagacacaauaaggauugacagauug
agagcucuuucuugauuuugugggugguggugcauggccguucuuaguug
guggagugauuugucugcuuaauugcgauaacgaacgagaccuuaaccua
cuaaauagugcugcuagcauuugcugguauagucacuucuuagagggacu
aucgauuucaagucgauggaaguuugaggcaauaacaggucugugaugcc
cuuagacguucugggccgcacgcgcgcuacacugacggagccagcgagua
uaagccuuggccgagaggucugggaaaucuugugaaacuccgucgugcug
gggauagagcauuguaauuguugcucuucaacgaggaauuccuaguaagc
gcaagucaucagcuugcguugauuacgucccugcccuuuguacacaccgc
ccgucgcuacuaccgauugaauggcuuagugaggccuccggauugguuua
uucuggaaccgagaagcuggucaaacuuggucauuuagaggaaguaaaag
ucguaacaagguuuccguaggugaaccugcggaaggaucau
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<............<<.....<..<<..
.....>>..>......>>........<<<<<..<<....>>..>>>>><.
..<<<<<<.......((((((.<<<....>>>..............>>>>
>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>
>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>
>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>
>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<<...>
>>>..>>>..>....>.>.....<<<<<<<<.<<<<....>>>>.>>>>>
.>>>......<<..<...........>..>>.........<<<<<((...
...<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>>.
........<<<[[.....<.<<...<<<.<<....<<<<<<<<<<.....
..............>>>>>>>>>>.....<<<<...........>>>>..
..<<<<<.<<.......<<...<.......>..<<<....>>>....>>.
.....>>.>>..>>>.........<<<..<<<<<<<<......)))))).
..>>>>>>>>>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<
<<.<...<<<......>>>......>.>>>>>>..>>.......<<....
>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<.
..<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<
..<<<<<<<<..<<........>>.>>>>>>>>..>>>...<<..]]>>.
..>>.....>>>.>>>.<<<......<<<<....>>>>....>>>..]]]
].}<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<...
.....>>..........<<<<<......<<<<<........<<.<<<...
.....>>>.>>......>>>>>...<<.<<<..<<.<<<<<.....<<<.
<<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<..
<<<<..<<<<.<<<<<<<....>>>>>>>....>>>>..>>>>.>>....
<<<<<<.....>>>>>>.......>>>>>.....>>.>>>.....>>>>>
>>.......>>>>>...>>.>>>>.>>>.....<<<<<<<......<<..
....<<<.<<<<....>>>>.>>>....>>.......>>>>>>>......
<....<<<<<<..........>>>>>>....>.....>>>>>>....<<<
<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<.
.<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<..<...<<<<<...
.......>>>>>...>..>>>>..>>>.>>>>>>>>...>>.>>>>...>
.>>...>.....<<<<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cqw Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.05 Å
Binding residue
(original residue number in PDB)
G2 K3 R10 G12 K13 V14 K15 T18 V21 K23 E25 K26 K28 P30 Q31 R33 A34 Y35 M36 R37 R42 R43 V45 N46 M56 N57 S59
Binding residue
(residue number reindexed from 1)
G1 K2 R9 G11 K12 V13 K14 T17 V20 K22 E24 K25 K27 P29 Q30 R32 A33 Y34 M35 R36 R41 R42 V44 N45 M55 N56 S58
External links
PDB RCSB:8cqw, PDBe:8cqw, PDBj:8cqw
PDBsum8cqw
PubMed
UniProtA0A1D8PSK2|RS30_CANAL Small ribosomal subunit protein eS30 (Gene Name=RPS30)

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