Structure of PDB 6zvj Chain g Binding Site BS01

Receptor Information
>6zvj Chain g (length=138) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLL
GKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEI
KDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR
Ligand information
>6zvj Chain 2 (length=1720) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucguacuuggauaacugugguaa
uucuagagcuaauacaugccgacgggcgcugacccccuucgcggggggga
ugcgugcauuuaucaguggugacucuagauaaccucgggccgaucgcacg
ccgcggcgacgacccauucgaacgucugcccuaucaacuuucgaugguag
ucgccgugccuaccauggugaccacgggugacggggaaucaggguucgau
uccggagagggagccugagaaacggcuaccacauccaaggaaggcagcag
gcgcgcaaauuacccacucccgacccggggagguagugacgaaaaauaac
aauacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaau
ccuuuaacgaggauccauuggagggcaagucuggugccagcagccgcggu
aauuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcucg
uaguuggaucuugggagcgggcgggcgguccgccgcgaggcgagccaccg
cccguccccgccucucggccgaagcguuuacuuugaaaaaauuagagugu
ucaaagcaggccgccuggauaccgcagcuaggaauaauggaauaggaccg
cgguucuauuuuguugguuuucggaacugaggccaugauuaagagggacg
gccgggggcauucguauugcgccgcuagaggugaaauucuuggaccggcg
caagacggaccagagcgaaagcauuugccaagaauguuuucauuaaucaa
gaacgaaagucggagguucgaagacgaucagauaccgucguaguuccgac
cauaaacgaugccgaccggcgaugcggcggcguuauucccaugacccgcc
gggcagcuuccgggaaaccaaagucuuuggguuccggggggaguaugguu
gcaaagcugaaacuuaaaggaauugacggaagggcaccaccaggagugga
gccugcggcuuaauuugacucaacacgggaaaccucacccggcccggaca
cggacaggauugacagauugauagcucuuucucgauuccguggguggugg
ugcauggccguucuuaguugguggagcgauuugucugguuaauuccgaua
acgaacgagacucuggcaugcuaacuaguuacgcgaccggucggcguaac
uucuuagagggacaaguggcguucagccacccgagauugagcaauaacag
gucugugaugcccuuagauguccggggcugcacgcgcgcuacacugacug
gcucagcgugugccuacccuacgccggcaggcgcggguaacccguugaac
cccauucgugauggggaucggggauugcaauuauuccccaugaacgagga
auucccaguaagugcgggucauaagcuugcguugauuaagucccugcccu
uuguacacaccgcccgucgcuacuaccgauuggaugguuuagugaggccc
ucggaucggccccgccggggugcccuggcggagcgcugagaagacggucg
aacuugacuaucuagaggaaguaaaagucguaacaagguuuccguaggua
aaccugcggaaggaucauua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<....<<....<<<<<.........<<.....<<.<<<...
..>>>.>>......>>.........<<<<...<<<<<.....>.>>>>..
.>>>><<..<<<<<...<......>..>>>>>......>>...<<<<.<<
<.>>>>>>>.>>.>>>...>>..>.>>>.<<<....<<<....<<<<<<<
.........>>>>>>>>>>......>>>...<<<.<<<<....>>>>...
.>>>.>>.<<.<<<..........>>>.>>...<<....>>.....>>>>
>>.........<<<....<<<<...>>>>..>>>..>...>>.>.....<
<<<<<<<<.<<......>>..>>>>>>.>>>......<<..<........
...>..>>.........<<<<<((....<.<<<<.....<<..))>>...
....>>>>>>>>>>..>>>>>>.>>>.........<..((.....<.<<.
..<<<.<<.....<<.<.<<<<<<<<<<<.<<<<....>>>>.>...>>>
>>>>>>>.>.>>..<......>.....<<<<<<.<.......<<...<..
.....>.<<<<.>>>>...>>......>.>>>..>>>........<.<<.
<<<<<<.................>>>>>>.>>.>....>>....<<<<<<
..<...<<<<..<<..<<<<<<<<...<<<......>>>......>>>>>
>>>..>>.......<<....>>...>>>>..>..>>>.>>>...>>>...
>>.>....<<<<<<<...<...<<<<.........>>>>...>>>>>>>>
..........<<<.<<.<<<..<.<<<<<<.<<<<<....>>>>>>>>>>
>.>..>>>...<<..))>>...>>.....>>>...>.<<<......<<<<
....>>>>....>>>..)))).]<<<<<.<<<<<<<..<<..<<<<<..<
<<.<<<<<<......<<........>>..........<<<<<......<<
<<<<.......<<.<<<........>>>.>>.....>>>>>>...<<.<<
<..<<.<<<<<.....<<<.<<<<<....>>>...<<<......>>>...
>>.>>>....<<<...<...<<<<..<<<<<<<<<<<..>>>.>>>>>>>
>..>>>>..>.....<<<<<.....>>>>>........>>>.....>>.>
>>.....>>>>>>>.......>>>>>...>>.>>>>.>>>.....<<.<<
<........<.......<<<.<<<<....>>>>.>>>....>........
.>>>.>>............<<<<<..........>>>>>...........
>>>>>.....<<<<<<<<.......>>>>>>>>......>>...>>>>>>
>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.
<<...<<<<.<<.................>..>..>>>>...>>.>>>>.
.>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<..
..>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zvj A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		Q11 V12 F13 K16 K17 T18 K26 R37 E43 R71 K73 G74 G75 G76 H77 V78 A79 R117 R125 R126 C127 E128 S129 K130 K131 F132 G136 A137 R138 A139 Y141 Q142 K143 S144 Y145 R146
Binding residue
(residue number reindexed from 1)		Q3 V4 F5 K8 K9 T10 K18 R29 E35 R63 K65 G66 G67 G68 H69 V70 A71 R109 R117 R118 C119 E120 S121 K122 K123 F124 G128 A129 R130 A131 Y133 Q134 K135 S136 Y137 R138
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006364 rRNA processing
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
GO:1990830 cellular response to leukemia inhibitory factor
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0015935 small ribosomal subunit
GO:0016020 membrane
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:0045202 synapse
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zvj, PDBe:6zvj, PDBj:6zvj
PDBsum6zvj
PubMed33289941
UniProtP62249|RS16_HUMAN Small ribosomal subunit protein uS9 (Gene Name=RPS16)

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